Age
Item
at least 18 years old
boolean
C0001779 (UMLS CUI [1])
Advanced life-limiting illness
Item
have an advanced life-limiting illness
boolean
C0012634 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C0439801 (UMLS CUI [1,3])
C0023671 (UMLS CUI [1,4])
Life expectancy | functional status worsening pattern recent | Karnofsky Performance Status
Item
have a life expectancy of >1 month, and patient exhibits declining functional status, defined as a reduction in australia-modified karnofsky performance status (akps)22 score to <80 % in the previous 3 months
boolean
C0023671 (UMLS CUI [1])
C0598463 (UMLS CUI [2,1])
C0332271 (UMLS CUI [2,2])
C0332185 (UMLS CUI [2,3])
C0206065 (UMLS CUI [3])
Statin prophylaxis cardiovascular disease duration
Item
statin medication for primary or secondary prevention of cardiovascular disease for ≥3 months;
boolean
C0360714 (UMLS CUI [1,1])
C0199176 (UMLS CUI [1,2])
C0007222 (UMLS CUI [1,3])
C0449238 (UMLS CUI [1,4])
Cognitive functions informed consent | baseline assessment | mental status questionnaire
Item
have adequately intact cognitive status to provide informed consent and complete the baseline assessment, as evidenced by a short portable mental status questionnaire (spmsq)23 score of ≥6;
boolean
C0392335 (UMLS CUI [1,1])
C0021430 (UMLS CUI [1,2])
C0392335 (UMLS CUI [2,1])
C1442488 (UMLS CUI [2,2])
C1516048 (UMLS CUI [2,3])
C0451291 (UMLS CUI [3])
Informed consent
Item
provide informed consent
boolean
C0021430 (UMLS CUI [1])
English literacy
Item
speak and read english at or above a grade 5 level (per patient or caregiver report)
boolean
C0564215 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
C0586740 (UMLS CUI [2,1])
C0376245 (UMLS CUI [2,2])
Estimated life expectancy by clinician
Item
primary treating physician/care provider estimates patient's life expectancy as <1 month
boolean
C0023671 (UMLS CUI [1,1])
C0022423 (UMLS CUI [1,2])
C1710470 (UMLS CUI [1,3])
Primary clinician unwilling to enroll patient
Item
under the care of a primary treating physician/primary care provider who is unwilling to have the patient enrolled;
boolean
C2348568 (UMLS CUI [1,1])
C0871685 (UMLS CUI [1,2])
C0034866 (UMLS CUI [1,3])
C1136454 (UMLS CUI [1,4])
Not consenting
Item
not consenting
boolean
C0021430 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Cardiovascular disease | heart disease risk factors | requirement statin drugs judgment treating physician
Item
having known active cardiovascular disease or sufficient risk of active cardiovascular disease to require ongoing therapy with statin drugs, in the opinion of the treating physician
boolean
C0007222 (UMLS CUI [1])
C0850624 (UMLS CUI [2])
C1514873 (UMLS CUI [3,1])
C0360714 (UMLS CUI [3,2])
C0022423 (UMLS CUI [3,3])
C1710470 (UMLS CUI [3,4])
Myositis | liver function abnormal | ck measurement abnormal | Medical contraindications to statin treatment
Item
exhibiting obvious symptoms of myositis, known liver function test (lft) abnormalities of >2.5x the upper limit of normal (uln), known creatine kinase (ck) abnormalities of >2.5x uln, or other contraindications to continuing statins, in the opinion of the treating physician
boolean
C0027121 (UMLS CUI [1])
C0232741 (UMLS CUI [2,1])
C0205161 (UMLS CUI [2,2])
C0201973 (UMLS CUI [3,1])
C0205161 (UMLS CUI [3,2])
C1301624 (UMLS CUI [4,1])
C0360714 (UMLS CUI [4,2])