Signed informed consent form
Item
signed informed consent form
boolean
C0021430 (UMLS CUI [1])
Ability to meet study requirements
Item
adhere to the study visit schedule and other protocol requirements
boolean
C0525058 (UMLS CUI [1])
active multiple myeloma
Item
diagnosed with active multiple myeloma
boolean
C0205177 (UMLS CUI [1,1])
C0026764 (UMLS CUI [1,2])
previously untreated
Item
myeloma previously untreated
boolean
C0332155 (UMLS CUI [1,1])
C0026764 (UMLS CUI [1,2])
karnofsky performance status
Item
karnofsky performance status(kps) ≥50
boolean
C0206065 (UMLS CUI [1])
karnofsky performance status
Item
karnofsky performance status (kps) <50 related to bony disease
boolean
C0206065 (UMLS CUI [1,1])
C0439849 (UMLS CUI [1,2])
C0005940 (UMLS CUI [1,3])
new york heart association
Item
new york heart association (nyha) functional ≤ class iii
boolean
C1275491 (UMLS CUI [1])
hypersensitivity to clarithromycin or any of its excipients, erythromycin, or any of the macrolide antibiotics
Item
hypersensitivity to clarithromycin or any of its excipients, erythromycin, or any of the macrolide antibiotics;
boolean
C0020517 (UMLS CUI [1,1])
C0055856 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0055856 (UMLS CUI [2,2])
C0015237 (UMLS CUI [2,3])
C0020517 (UMLS CUI [3,1])
C0014806 (UMLS CUI [3,2])
C0020517 (UMLS CUI [4,1])
C0003240 (UMLS CUI [4,2])
concomitant administration of cisapride, pimozide, astemizole, terfenadine, ergotamine or dihydroergotamine, simvastatin, lovastatin, and atorvastatin
Item
concomitant administration of cisapride, pimozide, astemizole, terfenadine, ergotamine or dihydroergotamine, simvastatin, lovastatin, and atorvastatin;
boolean
C2347852 (UMLS CUI [1,1])
C0072916 (UMLS CUI [1,2])
C2347852 (UMLS CUI [2,1])
C0031935 (UMLS CUI [2,2])
C2347852 (UMLS CUI [3,1])
C0085170 (UMLS CUI [3,2])
C2347852 (UMLS CUI [4,1])
C0085173 (UMLS CUI [4,2])
C2347852 (UMLS CUI [5,1])
C0014710 (UMLS CUI [5,2])
C2347852 (UMLS CUI [6,1])
C0012291 (UMLS CUI [6,2])
C2347852 (UMLS CUI [7,1])
C0074554 (UMLS CUI [7,2])
C2347852 (UMLS CUI [8,1])
C0024027 (UMLS CUI [8,2])
C2347852 (UMLS CUI [9,1])
C0286651 (UMLS CUI [9,2])
previous cholestatic jaundice/hepatic dysfunction linked to use of clarithromycin
Item
a history of cholestatic jaundice/hepatic dysfunction associated with prior use of clarithromycin
boolean
C0205156 (UMLS CUI [1,1])
C0008370 (UMLS CUI [1,2])
C0022346 (UMLS CUI [1,3])
C0332281 (UMLS CUI [1,4])
C0055856 (UMLS CUI [1,5])
C0205156 (UMLS CUI [2,1])
C0086565 (UMLS CUI [2,2])
C0332281 (UMLS CUI [2,3])
C0055856 (UMLS CUI [2,4])
abnormal renal function, creatinine
Item
impaired renal function,creatinine ≥221umol/l;
boolean
C0201976 (UMLS CUI [1])
C0151746 (UMLS CUI [2])
pregnant or breast feeding
Item
pregnant or breast feeding females
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
condition placing the subject at unacceptable risk in case of study participation or confounds the study's data interpretation
Item
any condition which places the subject at unacceptable risk if he/she were to participate in the study or confounds the ability to interpret data from the study.
boolean
C0012634 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C1883420 (UMLS CUI [1,3])
C0035647 (UMLS CUI [1,4])
C0012634 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C0681873 (UMLS CUI [2,3])
C0459471 (UMLS CUI [2,4])