Adult | Age
Item
adult patients, >/= 18 years of age
boolean
C0001675 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Diffuse Large B-Cell Lymphoma CD20 positive Untreated
Item
previously untreated cd20-positive diffuse large b-cell lymphoma (dlbcl)
boolean
C0079744 (UMLS CUI [1,1])
C3888518 (UMLS CUI [1,2])
C0332155 (UMLS CUI [1,3])
Measurable Disease 2-Dimensional Quantity | Lesion size, largest dimension CT scan
Item
at least 1 bi-dimensionally measurable lesion (>1.5 cm in is largest dimension on the ct scan)
boolean
C1513041 (UMLS CUI [1,1])
C1705052 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C1275593 (UMLS CUI [2,1])
C0040405 (UMLS CUI [2,2])
ECOG performance status
Item
eastern cooperative oncology group (ecog) performance status 0, 1 or 2
boolean
C1520224 (UMLS CUI [1])
Hematologic function
Item
adequate hematological function
boolean
C0221130 (UMLS CUI [1])
International Prognostic Index Low-Intermediate Risk Group | Risk Intermediate International Prognostic Index | High risk International Prognostic Index | Bulky Disease | Lesion size Quantity
Item
low-intermediate, intermediate or high-risk ipi score (low-risk ipi score: ipi 1 irrespective of bulky disease or ipi 0 with bulky disease, defined as one lesion >/= 7.5 cm)
boolean
C5206109 (UMLS CUI [1])
C0035647 (UMLS CUI [2,1])
C0205103 (UMLS CUI [2,2])
C1512894 (UMLS CUI [2,3])
C4319571 (UMLS CUI [3,1])
C1512894 (UMLS CUI [3,2])
C1511341 (UMLS CUI [4])
C0449453 (UMLS CUI [5,1])
C1265611 (UMLS CUI [5,2])
Allergic Reaction Severe Humanized Monoclonal Antibodies | Anaphylaxis Severe Humanized Monoclonal Antibodies | Allergic Reaction Severe Monoclonal Antibodies Murine | Anaphylaxis Severe Monoclonal Antibodies Murine | Hypersensitivity Product Murine
Item
history of severe allergic or anaphylactic reactions to humanized or murine monoclonal antibodies or known sensitivity or allergy to murine products
boolean
C1527304 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C2985546 (UMLS CUI [1,3])
C0002792 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C2985546 (UMLS CUI [2,3])
C1527304 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0003250 (UMLS CUI [3,3])
C0026809 (UMLS CUI [3,4])
C0002792 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
C0003250 (UMLS CUI [4,3])
C0026809 (UMLS CUI [4,4])
C0020517 (UMLS CUI [5,1])
C1254351 (UMLS CUI [5,2])
C0026809 (UMLS CUI [5,3])
Medical contraindication Component CHOP regimen | Medical contraindication Anthracyclines
Item
contraindication to any of the individual components of chop, including prior receipt of anthracyclines
boolean
C1301624 (UMLS CUI [1,1])
C1705248 (UMLS CUI [1,2])
C0163868 (UMLS CUI [1,3])
C1301624 (UMLS CUI [2,1])
C0282564 (UMLS CUI [2,2])
Lymphoma Transformation | Follicular Lymphoma Ann Arbor lymphoma staging system
Item
patients with transformed lymphoma and patients with follicular lymphoma iiib
boolean
C0024299 (UMLS CUI [1,1])
C0040682 (UMLS CUI [1,2])
C0024301 (UMLS CUI [2,1])
C0432516 (UMLS CUI [2,2])
Prior Therapy Diffuse Large B-Cell Lymphoma | Exception Biopsy of lymph node | Exception Therapeutic radiology procedure Local
Item
prior therapy for dlbcl, with the exception of nodal biopsy or local irradiation
boolean
C1514463 (UMLS CUI [1,1])
C0079744 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0193842 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C1522449 (UMLS CUI [3,2])
C0205276 (UMLS CUI [3,3])
Cytotoxic agent | rituximab | Anti-CD20 Antibody
Item
prior treatment with cytotoxic drugs or rituximab for another condition (e.g., rheumatoid arthritis) or prior use of an anti-cd20 antibody
boolean
C0304497 (UMLS CUI [1])
C0393022 (UMLS CUI [2])
C3891557 (UMLS CUI [3])
Monoclonal Antibodies
Item
prior use of any monoclonal antibody within 3 months of the start of cycle 1
boolean
C0003250 (UMLS CUI [1])
Steroid therapy | Prednisone U/day | Equivalent
Item
ongoing corticosteroid use of > 30 mg/day of prednisone or equivalent
boolean
C0149783 (UMLS CUI [1])
C0032952 (UMLS CUI [2,1])
C0456683 (UMLS CUI [2,2])
C0205163 (UMLS CUI [3])
Primary central nervous system lymphoma | Mantle-cell lymphoma | Transformation Burkitt Lymphoma | Mediastinal (Thymic) Large B-Cell Lymphoma | Primary Effusion Lymphoma | Primary cutaneous diffuse large cell B-cell lymphoma
Item
primary cns lymphoma, blastic variant of mantle-cell lymphoma, or histologic evidence of transformation to a burkitt lymphoma, primary mediastinal dlbcl, primary effusion lymphoma, and primary cutaneous dlbcl
boolean
C0280803 (UMLS CUI [1])
C0334634 (UMLS CUI [2])
C0040682 (UMLS CUI [3,1])
C0006413 (UMLS CUI [3,2])
C1292754 (UMLS CUI [4])
C1292753 (UMLS CUI [5])
C1275325 (UMLS CUI [6])
HIV Seropositivity
Item
positive for hiv
boolean
C0019699 (UMLS CUI [1])
Hepatitis B | Hepatitis C
Item
active hepatitis b or c infection
boolean
C0019163 (UMLS CUI [1])
C0019196 (UMLS CUI [2])