Nasal NK/T-cell lymphoma TNM clinical staging
Item
1. patients with newly diagnosed stage i and ii nasal natural killer (nk) cell lymphoma.
boolean
C0558916 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
Blood Cell Count | Absolute neutrophil count | Transfusion | filgrastim | Erythropoietin | Therapeutic radiology procedure Absent
Item
2. adequate blood cell counts (i.e. absolute neutrophil count (anc)> 1000) at baseline, or willingness to accept supportive measures such as transfusions, filgrastim, and epoetin. epoetin will not be administered concurrently with radiation.
boolean
C0005771 (UMLS CUI [1])
C0948762 (UMLS CUI [2])
C0005841 (UMLS CUI [3])
C0210630 (UMLS CUI [4])
C0014822 (UMLS CUI [5])
C1522449 (UMLS CUI [6,1])
C0332197 (UMLS CUI [6,2])
Liver function | Serum total bilirubin measurement | Alanine aminotransferase measurement | Aspartate aminotransferase measurement
Item
3. patients must have adequate liver function as indicated by: *bilirubin </= 1.5 times the upper limit of normal (uln), * alanine transaminase (alt) </= 2 times the (uln) or aspartate transaminase (ast) ≤ 2 times the uln, *these values must be obtained within two weeks before protocol entry.
boolean
C0232741 (UMLS CUI [1])
C1278039 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
C0201899 (UMLS CUI [4])
Renal function | Creatinine measurement, serum
Item
4. patients are required to have adequate renal function as indicated by a serum creatinine </= 2.5 mg/dl.this value must be obtained within two weeks before protocol entry.
boolean
C0232804 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
Left ventricular ejection fraction Radionuclide Imaging | Left ventricular ejection fraction Echocardiography
Item
5. left ventricular ejection fraction must be evaluated by nuclear medicine scan or echocardiography and measure >/= 50%.
boolean
C0428772 (UMLS CUI [1,1])
C0034606 (UMLS CUI [1,2])
C0428772 (UMLS CUI [2,1])
C0013516 (UMLS CUI [2,2])
Gender Barrier Contraception | Gender Sexual Abstinence Coitus
Item
6. male patients must agree to use a barrier method of contraception or agree to abstain from heterosexual activity for the duration of the study.
boolean
C0079399 (UMLS CUI [1,1])
C0004764 (UMLS CUI [1,2])
C0079399 (UMLS CUI [2,1])
C0036899 (UMLS CUI [2,2])
C0009253 (UMLS CUI [2,3])
Gender Barrier Contraception Quantity | Gender Sexual Abstinence Coitus | Postmenopausal state | Female Sterilization
Item
7. female patients must be willing to use two adequate barrier methods of contraception to prevent pregnancy or agree to abstain from heterosexual activity throughout the study or be post menopausal (free from menses > two years or surgically sterilized).
boolean
C0079399 (UMLS CUI [1,1])
C0004764 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0079399 (UMLS CUI [2,1])
C0036899 (UMLS CUI [2,2])
C0009253 (UMLS CUI [2,3])
C0232970 (UMLS CUI [3])
C0015787 (UMLS CUI [4])
Childbearing Potential Serum pregnancy test (B-HCG) Negative
Item
8. female patients of childbearing potential must have a negative serum pregnancy test (bhcg) within 2 weeks of protocol entry.
boolean
C3831118 (UMLS CUI [1,1])
C0430060 (UMLS CUI [1,2])
C1513916 (UMLS CUI [1,3])
Informed Consent
Item
9. patients must have the ability to give informed consent.
boolean
C0021430 (UMLS CUI [1])
Hepatitis B | Hepatitis C
Item
1. patients with active hepatitis b and/or hepatitis c infection.
boolean
C0019163 (UMLS CUI [1])
C0019196 (UMLS CUI [2])
Communicable Disease Requirement Anti-infective therapy
Item
2. patients with active infections requiring specific anti-infective therapy are not eligible until all signs of infections are resolved.
boolean
C0009450 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C1141958 (UMLS CUI [1,3])
HIV Seropositivity
Item
3. patients known to be hiv positive.
boolean
C0019699 (UMLS CUI [1])
Cardiovascular Disease Treatment required for | Congestive heart failure New York Heart Association Classification | Cardiomyopathy | Cardiac Arrhythmia Uncontrolled | Angina, Unstable | Myocardial Infarction
Item
4. patients with pre-existing cardiovascular disease requiring ongoing treatment. this includes: a) congestive heart failure class iii/iv (chf) per new york heart association (nyha) criteria. b) cardiomyopathy, c) uncontrolled cardiac arrhythmia, d) unstable angina pectoris, e) recent myocardial infarction (mi) (within 6 months).
boolean
C0007222 (UMLS CUI [1,1])
C0332121 (UMLS CUI [1,2])
C0018802 (UMLS CUI [2,1])
C1275491 (UMLS CUI [2,2])
C0878544 (UMLS CUI [3])
C0003811 (UMLS CUI [4,1])
C0205318 (UMLS CUI [4,2])
C0002965 (UMLS CUI [5])
C0027051 (UMLS CUI [6])
Exposure to Anthracyclines
Item
5. patients with prior exposure to anthracyclines:
boolean
C0332157 (UMLS CUI [1,1])
C0282564 (UMLS CUI [1,2])
Pregnancy | Breast Feeding
Item
6. patients who are pregnant or breast-feeding.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Mental disorders Limiting Medication Compliance | Social situation Limiting Medication Compliance | Mental disorders Limiting Protocol Compliance | Social situation Limiting Protocol Compliance
Item
7. patients with psychiatric illness and/or social situations that would limit compliance with the study medication and requirements.
boolean
C0004936 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C3489773 (UMLS CUI [1,3])
C0748872 (UMLS CUI [2,1])
C0439801 (UMLS CUI [2,2])
C3489773 (UMLS CUI [2,3])
C0004936 (UMLS CUI [3,1])
C0439801 (UMLS CUI [3,2])
C0525058 (UMLS CUI [3,3])
C0748872 (UMLS CUI [4,1])
C0439801 (UMLS CUI [4,2])
C0525058 (UMLS CUI [4,3])
Prior Radiation Therapy Site Disease Current
Item
8. prior radiation to the site of current primary disease, if re-treatment would lead to violation of known radiation dose tolerance limits for that site.
boolean
C0279134 (UMLS CUI [1,1])
C1515974 (UMLS CUI [1,2])
C0012634 (UMLS CUI [1,3])
C0521116 (UMLS CUI [1,4])