Follicular Lymphoma Grade
Item
histologically confirmed* grade 1, 2, or 3 follicular b-cell non-hodgkin lymphoma meeting the following criteria:
boolean
C0024301 (UMLS CUI [1,1])
C0441800 (UMLS CUI [1,2])
Disease TNM clinical staging
Item
bulky stage ii or stage iii or iv disease
boolean
C0012634 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
Diffuse Large B-Cell Lymphoma Component | Percentage Biopsy
Item
diffuse large cell component must be < 25% of the biopsy
boolean
C0079744 (UMLS CUI [1,1])
C1705248 (UMLS CUI [1,2])
C0439165 (UMLS CUI [2,1])
C0005558 (UMLS CUI [2,2])
Disease CD20 positive
Item
confirmed cluster of differentiation antigen 20 (cd20) antigen-positive disease note: *needle aspiration or cytology are not considered adequate for pathology review
boolean
C0012634 (UMLS CUI [1,1])
C3888518 (UMLS CUI [1,2])
Marrow aspirate Unilateral | Marrow aspirate Bilateral | Biopsy
Item
patient must have unilateral or bilateral bone marrow aspirate and biopsy performed within 42 days
boolean
C0857285 (UMLS CUI [1,1])
C0205092 (UMLS CUI [1,2])
C0857285 (UMLS CUI [2,1])
C0238767 (UMLS CUI [2,2])
C0005558 (UMLS CUI [3])
Biopsy Performed Positive
Item
positive biopsy performed > 42 days but < 6 months allowed
boolean
C0005558 (UMLS CUI [1,1])
C0884358 (UMLS CUI [1,2])
C1514241 (UMLS CUI [1,3])
Disease Untreated
Item
previously untreated disease
boolean
C0012634 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
Measurable Disease 2-Dimensional
Item
bidimensionally measurable disease
boolean
C1513041 (UMLS CUI [1,1])
C1705052 (UMLS CUI [1,2])
Absence Central Nervous System Involvement Lymphoma
Item
no clinical evidence of central nervous system (cns) involvement by lymphoma
boolean
C0332197 (UMLS CUI [1,1])
C4050309 (UMLS CUI [1,2])
C0024299 (UMLS CUI [1,3])
Client Characteristics
Item
patient characteristics:
boolean
C0815172 (UMLS CUI [1])
Zubrod Performance Status
Item
zubrod performance status 0-2
boolean
C3714786 (UMLS CUI [1])
Cardiac ejection fraction MUGA scan | Cardiac ejection fraction Echocardiography
Item
cardiac ejection fraction ≥ 45% by multigated acquisition scan (muga) or echo
boolean
C0232174 (UMLS CUI [1,1])
C0521317 (UMLS CUI [1,2])
C0232174 (UMLS CUI [2,1])
C0013516 (UMLS CUI [2,2])
Cardiac abnormalities Absent
Item
no significant cardiac abnormalities
boolean
C0018798 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
HIV Seropositivity Absent
Item
no known hiv positivity
boolean
C0019699 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Requirement Absent Supplemental oxygen therapy
Item
no requirement for continuous supplemental oxygen therapy
boolean
C1514873 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0184633 (UMLS CUI [1,3])
Cancer Other Absent | Exception Basal cell carcinoma Treated | Exception Squamous cell carcinoma of skin Treated | Exception Carcinoma in situ of uterine cervix Treated | Exception Malignant Neoplasm TNM clinical staging Treated | Exception Malignant Neoplasm In complete remission
Item
no other malignancy within the past 5 years except adequately treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix, or adequately treated stage i or ii cancer from which the patient is currently in complete remission
boolean
C1707251 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1522326 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0553723 (UMLS CUI [3,2])
C1522326 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C0851140 (UMLS CUI [4,2])
C1522326 (UMLS CUI [4,3])
C1705847 (UMLS CUI [5,1])
C0006826 (UMLS CUI [5,2])
C3258246 (UMLS CUI [5,3])
C1522326 (UMLS CUI [5,4])
C1705847 (UMLS CUI [6,1])
C0006826 (UMLS CUI [6,2])
C0677874 (UMLS CUI [6,3])
Pregnancy Absent | Breast Feeding Absent
Item
not pregnant or nursing
boolean
C0032961 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0006147 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Females & males of reproductive potential Contraceptive methods
Item
fertile patients must use effective contraception during and for 12 months after completion of maintenance therapy
boolean
C4034483 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Prior Therapy
Item
prior concurrent therapy:
boolean
C1514463 (UMLS CUI [1])
Prior Chemotherapy Absent Lymphoma | Prior Radiation Therapy Absent Lymphoma | Antibody Therapy Absent Lymphoma
Item
no prior chemotherapy, radiotherapy, or antibody therapy for lymphoma
boolean
C1514457 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0024299 (UMLS CUI [1,3])
C0279134 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0024299 (UMLS CUI [2,3])
C0281176 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C0024299 (UMLS CUI [3,3])
Solid organ transplant Absent
Item
no prior solid organ transplantation
boolean
C0730400 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])