Non-Small Cell Lung Carcinoma
Item
1. histologically proven non small cell lung cancer
boolean
C0007131 (UMLS CUI [1])
Non-Small Cell Lung Carcinoma TNM clinical staging Inoperable
Item
2. inoperable tage iiia or iiib non small cell lung cancer
boolean
C0007131 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
C0205187 (UMLS CUI [1,3])
Age
Item
3. age ≥ 18 years
boolean
C0001779 (UMLS CUI [1])
Life Expectancy
Item
4. perflife expectancy ≥6 months
boolean
C0023671 (UMLS CUI [1])
Hematologic function | Neutrophil count | Platelet Count measurement
Item
5. hematological function : neutrophils ≥1500/mm3 and platelets ≥ 100000/mm3
boolean
C0221130 (UMLS CUI [1])
C0200633 (UMLS CUI [2])
C0032181 (UMLS CUI [3])
Liver function | Serum bilirubin normal | Aspartate aminotransferase measurement | Alanine aminotransferase measurement
Item
6. hepatic function: bilirubin within normal limits et ast and alt ≤ 2 times the upper limit of normal (uln).
boolean
C0232741 (UMLS CUI [1])
C0428443 (UMLS CUI [2])
C0201899 (UMLS CUI [3])
C0201836 (UMLS CUI [4])
Renal function | Creatinine measurement, serum
Item
7. renal function: creatinine ≤ 1.5 times uln.
boolean
C0232804 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
Heart failure Absent | Unstable Angina Absent | Cardiac Arrhythmia Absent
Item
8. absence of cardiac insufficiency, absence of unstable angina, absence of arrythmia
boolean
C0018801 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0002965 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0003811 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
Health Insurance coverage
Item
9. patient has health insurance coverage.
boolean
C0021682 (UMLS CUI [1,1])
C1551362 (UMLS CUI [1,2])
Informed Consent
Item
10. signed informed consent.
boolean
C0021430 (UMLS CUI [1])
Prior Therapy Malignant Neoplasm | Chemotherapy | Therapeutic radiology procedure | Operative Surgical Procedure
Item
1. patients previously treated for a malignancy by means of chemotherapy, radiotherapy or surgery.
boolean
C1514463 (UMLS CUI [1,1])
C0006826 (UMLS CUI [1,2])
C0392920 (UMLS CUI [2])
C1522449 (UMLS CUI [3])
C0543467 (UMLS CUI [4])
Uncontrolled hypertension
Item
2. uncontrolled hypertension
boolean
C1868885 (UMLS CUI [1])
Bleeding uncontrolled
Item
3. uncontrolled bleeding within the last 3 months.
boolean
C3842135 (UMLS CUI [1])
Anticoagulation Therapy | Vitamin K Antagonist | Heparin Dose Therapeutic
Item
4. patients under anti-coagulation with anti-vitamin k or therapeutic dose heparin ; low-molecular heparins for prophylaxis are permitted and are not considered an exclusion criterion.
boolean
C0003281 (UMLS CUI [1])
C2267235 (UMLS CUI [2])
C0019134 (UMLS CUI [3,1])
C0178602 (UMLS CUI [3,2])
C0302350 (UMLS CUI [3,3])
Cerebral metastasis
Item
5. presence of cerebral metastases.
boolean
C0555278 (UMLS CUI [1])
Study Subject Participation Status | Clinical Trial
Item
6. participation in a clinical trial within the last 8 weeks.
boolean
C2348568 (UMLS CUI [1])
C0008976 (UMLS CUI [2])
Cancer treatment Specific | Chemotherapy | Therapeutic radiology procedure
Item
7. any other specific concomitant anti-tumor treatment (such as chemotherapy, radiotherapy …).
boolean
C0920425 (UMLS CUI [1,1])
C0205369 (UMLS CUI [1,2])
C0392920 (UMLS CUI [2])
C1522449 (UMLS CUI [3])
Myocardial Infarction | Cerebrovascular accident
Item
8. patients with a history of myocardial infarction or a cerebral vascular accident within the last 12 months.
boolean
C0027051 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
Aspirin U/day
Item
9. continued use of aspirin (>325mg/day)
boolean
C0004057 (UMLS CUI [1,1])
C0456683 (UMLS CUI [1,2])
Major surgery | Major surgery Planned
Item
10. major surgery whiting the last 28 days or planned.
boolean
C0679637 (UMLS CUI [1])
C0679637 (UMLS CUI [2,1])
C1301732 (UMLS CUI [2,2])
Non-healed Wound Major | Ulcer
Item
11. major non-healing wound, ulcer
boolean
C0750433 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
C0041582 (UMLS CUI [2])
Pregnancy | Breast Feeding | Childbearing Potential Pregnancy blood test Negative
Item
12. pregnant or breastfeeding women cannot participate in this trial. women of reproductive potential must have a negative pregnancy test (blood) within 72 hours before the start of treatment.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0850355 (UMLS CUI [3,2])
C1513916 (UMLS CUI [3,3])
Females & males of reproductive potential Contraceptive methods
Item
13. men and women of reproductive potential must use an efficient contraceptive method when entering the trial and until one months after the end of treatment.
boolean
C4034483 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Thromboembolism | Event Hemorrhagic
Item
14. history of a thrombo-embolic or hemorrhagic event.
boolean
C0040038 (UMLS CUI [1])
C0441471 (UMLS CUI [2,1])
C0333275 (UMLS CUI [2,2])
Patients Guardianship
Item
15. patients put under tutelage.
boolean
C0030705 (UMLS CUI [1,1])
C0870627 (UMLS CUI [1,2])
Protocol Compliance Unable
Item
16. patients not able to follow the procedures visits, exams foreseen by the trial.
boolean
C0525058 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Other medical condition Severe Study Subject Participation Status Inappropriate | Mental condition Severe Study Subject Participation Status Inappropriate | Abnormality Study Subject Participation Status Inappropriate | Abnormality chronic Study Subject Participation Status Inappropriate
Item
17. any other severe medical or psychiatric condition or biological anomaly - acute or chronic - that, in the investigator's opinion - may render the inclusion of the patient inappropriate.
boolean
C3843040 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C2348568 (UMLS CUI [1,3])
C1548788 (UMLS CUI [1,4])
C3840291 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C2348568 (UMLS CUI [2,3])
C1548788 (UMLS CUI [2,4])
C1704258 (UMLS CUI [3,1])
C2348568 (UMLS CUI [3,2])
C1548788 (UMLS CUI [3,3])
C1704258 (UMLS CUI [4,1])
C0205191 (UMLS CUI [4,2])
C2348568 (UMLS CUI [4,3])
C1548788 (UMLS CUI [4,4])