Able to speak English Language | Able to speak Spanish Language | Gender | Age
Item
english or spanish speaking women age ≥18
boolean
C0564215 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
C0564215 (UMLS CUI [2,1])
C0037750 (UMLS CUI [2,2])
C0079399 (UMLS CUI [3])
C0001779 (UMLS CUI [4])
Heart rate
Item
heart rate > 60 bpm
boolean
C0018810 (UMLS CUI [1])
Systolic Pressure
Item
systolic blood pressure > 100 mm/hg
boolean
C0871470 (UMLS CUI [1])
Neoadjuvant Chemotherapy | Chemotherapy cycle Quantity | taxane | Paclitaxel Dose | Abraxane Dose | Adriamycin Dose | Cyclophosphamide Dose | Growth Factor Support
Item
deemed eligible to receive neoadjuvant chemotherapy with 12 cycles of weekly taxane therapy (paclitaxel 80mg/m2 or abraxane 100 mg/m2 if there is a shortage of paclitaxel) followed by 4 cycles of adriamycin (60mg/m2) and cyclophosphamide (600 mg/m2) given every 2 weeks with growth-factor support.
boolean
C0600558 (UMLS CUI [1,1])
C3665472 (UMLS CUI [1,2])
C1302181 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0215136 (UMLS CUI [3])
C0144576 (UMLS CUI [4,1])
C0178602 (UMLS CUI [4,2])
C1564985 (UMLS CUI [5,1])
C0178602 (UMLS CUI [5,2])
C0085752 (UMLS CUI [6,1])
C0178602 (UMLS CUI [6,2])
C0010583 (UMLS CUI [7,1])
C0178602 (UMLS CUI [7,2])
C0018284 (UMLS CUI [8,1])
C1521721 (UMLS CUI [8,2])
Cardiac ejection fraction Echocardiography | Cardiac ejection fraction MUGA scan
Item
echocardiogram (echo) or multiple-gated acquisition scan (muga) with ejection fraction > 50%.
boolean
C0232174 (UMLS CUI [1,1])
C0013516 (UMLS CUI [1,2])
C0232174 (UMLS CUI [2,1])
C0521317 (UMLS CUI [2,2])
Hormone Receptor Positive Breast Carcinoma | Breast Carcinoma Hormone Receptor Negative | HER2-positive carcinoma of breast | HER2-negative breast cancer
Item
patients with hormone receptor +/- and human epidermal growth factor receptor 2 protein (her2) +/- breast cancer are eligible
boolean
C4745240 (UMLS CUI [1])
C0678222 (UMLS CUI [2,1])
C0019929 (UMLS CUI [2,2])
C1513916 (UMLS CUI [2,3])
C1960398 (UMLS CUI [3])
C4733095 (UMLS CUI [4])
HER2-positive carcinoma of breast | Herceptin | Perjeta | taxane
Item
if a patient has her2-positive breast cancer, herceptin and perjeta will be given along with taxane therapy
boolean
C1960398 (UMLS CUI [1])
C0338204 (UMLS CUI [2])
C3473371 (UMLS CUI [3])
C0215136 (UMLS CUI [4])
Invasive carcinoma of breast TNM Breast tumor staging | Breast Carcinoma Size
Item
any stage invasive breast cancer provided the primary breast tumor size is ≥ 1 cm
boolean
C0853879 (UMLS CUI [1,1])
C0474926 (UMLS CUI [1,2])
C0678222 (UMLS CUI [2,1])
C0456389 (UMLS CUI [2,2])
Collection of blood specimen
Item
agree to participate in research blood collection at 4 different time periods (20 ml = 4 teaspoons)
boolean
C0005834 (UMLS CUI [1])
Core biopsy Evaluation | Evaluation Tissue Excisional | Biomarkers
Item
agree to the evaluation of already collected core biopsy, as well as surgical resection tissue, for predictive biomarkers. the biopsy prior to taxol #1 is optional.
boolean
C1318309 (UMLS CUI [1,1])
C1261322 (UMLS CUI [1,2])
C1261322 (UMLS CUI [2,1])
C0040300 (UMLS CUI [2,2])
C0728940 (UMLS CUI [2,3])
C0005516 (UMLS CUI [3])
Inclusion criteria Failed
Item
patients failing to meet the inclusion criteria
boolean
C1512693 (UMLS CUI [1,1])
C0231175 (UMLS CUI [1,2])
Prolonged QTc interval on electrocardiogram (ECG)
Item
corrected qt interval (qtc) prolongation as defined by > 470 milliseconds on electrocardiogram (ecg)
boolean
C4015677 (UMLS CUI [1])
First degree atrioventricular block ECG | Second degree atrioventricular block ECG | Complete atrioventricular block ECG | Prolonged PR interval
Item
first degree av block on ecg in which pr interval lengthened > 200 milliseconds; second degree; or third degree
boolean
C0085614 (UMLS CUI [1,1])
C0013798 (UMLS CUI [1,2])
C0264906 (UMLS CUI [2,1])
C0013798 (UMLS CUI [2,2])
C0151517 (UMLS CUI [3,1])
C0013798 (UMLS CUI [3,2])
C0600125 (UMLS CUI [4])
Adrenergic beta-1 Receptor Antagonists
Item
on beta-blocker treatment. if discontinued, patients must have been off beta-blockers for at least 3 months.
boolean
C0304516 (UMLS CUI [1])
History of asthma
Item
history of asthma, given concern for β-blockade in this population
boolean
C0455544 (UMLS CUI [1])