Gender | Age
Item
women 18 years of age or older
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Medical contraindication Absent Zometa | Estimation of creatinine clearance by Cockcroft-Gault formula | Creatinine clearance measurement MDRD
Item
absence of contraindication to treatment with zometa: creatinine clearance greater than 30 ml/min (with cockroft or mdrd method).
boolean
C1301624 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0939788 (UMLS CUI [1,3])
C2711451 (UMLS CUI [2])
C0373595 (UMLS CUI [3,1])
C3839656 (UMLS CUI [3,2])
Breast Carcinoma TNM Breast tumor staging | Diameter Maximal | Benefit Due to Neoadjuvant Chemotherapy
Item
breast cancer (tnm iia, iib, iiia) larger than 2cm in maximal diameter able to benefit from neoadjuvant chemotherapy
boolean
C0678222 (UMLS CUI [1,1])
C0474926 (UMLS CUI [1,2])
C1301886 (UMLS CUI [2,1])
C0205289 (UMLS CUI [2,2])
C0814225 (UMLS CUI [3,1])
C0678226 (UMLS CUI [3,2])
C0600558 (UMLS CUI [3,3])
C3665472 (UMLS CUI [3,4])
Ductal Breast Carcinoma | Breast cancer, lobular
Item
ductal or lobular histological type of the breast tumor
boolean
C1527349 (UMLS CUI [1])
C3549742 (UMLS CUI [2])
WHO performance status scale
Item
who performance status 0-2
boolean
C1298650 (UMLS CUI [1])
Comprehension French language
Item
patient who understands the french language
boolean
C0233733 (UMLS CUI [1,1])
C0376246 (UMLS CUI [1,2])
Social Security coverage
Item
covered by, or having the right to social security
boolean
C0037435 (UMLS CUI [1,1])
C1551362 (UMLS CUI [1,2])
Informed Consent
Item
signed informed consent
boolean
C0021430 (UMLS CUI [1])
Breast Carcinoma Histologic type Rare | Exception Ductal Breast Carcinoma | Exception Lobular breast cancer
Item
breast cancers of rare histological type (other than ductal and lobular)
boolean
C0678222 (UMLS CUI [1,1])
C0449574 (UMLS CUI [1,2])
C0522498 (UMLS CUI [1,3])
C1705847 (UMLS CUI [2,1])
C1527349 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C3549742 (UMLS CUI [3,2])
Malignant Neoplasm Noninvasive
Item
noninvasive cancer
boolean
C0006826 (UMLS CUI [1,1])
C2986496 (UMLS CUI [1,2])
Multifocal tumor
Item
multifocal tumor (more than 2 tumoral lesions or 2 tumoral lesions distant more than 2cm each other)
boolean
C1302461 (UMLS CUI [1])
Breast Carcinoma TNM Breast tumor staging
Item
t4 breast tumor
boolean
C0678222 (UMLS CUI [1,1])
C0474926 (UMLS CUI [1,2])
Organ Neoplasm Metastasis | Secondary malignant neoplasm of bone | Secondary malignant neoplasm of skin
Item
presence of organ, bone, or skin metastases (in the initial staging workup)
boolean
C0178784 (UMLS CUI [1,1])
C0027627 (UMLS CUI [1,2])
C0153690 (UMLS CUI [2])
C0153687 (UMLS CUI [3])
History of Breast Carcinoma
Item
patient with a history of breast cancer
boolean
C0262926 (UMLS CUI [1,1])
C0678222 (UMLS CUI [1,2])
Therapeutic procedure Cancer Other | Exception Carcinoma in Situ
Item
other cancer currently in treatment (except carcinoma in situ).
boolean
C0087111 (UMLS CUI [1,1])
C1707251 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0007099 (UMLS CUI [2,2])
Systemic disease Severe Interferes with Follow-up
Item
severe systemic disease potentially interfering with follow-up.
boolean
C0442893 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0521102 (UMLS CUI [1,3])
C3274571 (UMLS CUI [1,4])
Medical contraindication Injectables | Allergy to bisphosphonate | Allergy to zoledronic acid | Hypersensitivity Diphosphonates Excipient | Hypersensitivity Zoledronic acid Excipient | Kidney Failure Severe | Estimation of creatinine clearance by Cockcroft-Gault formula | Creatinine clearance measurement MDRD
Item
contraindication to injected products: known allergy to bisphosphonates, zoledronic acid or excipients, severe renal failure (creatinine clearance < 30 ml/min with cockroft or mdrd method).
boolean
C1301624 (UMLS CUI [1,1])
C0086466 (UMLS CUI [1,2])
C0571738 (UMLS CUI [2])
C4544924 (UMLS CUI [3])
C0020517 (UMLS CUI [4,1])
C0012544 (UMLS CUI [4,2])
C0015237 (UMLS CUI [4,3])
C0020517 (UMLS CUI [5,1])
C0257685 (UMLS CUI [5,2])
C0015237 (UMLS CUI [5,3])
C0035078 (UMLS CUI [6,1])
C0205082 (UMLS CUI [6,2])
C2711451 (UMLS CUI [7])
C0373595 (UMLS CUI [8,1])
C3839656 (UMLS CUI [8,2])
Pregnancy | Pregnancy test positive | Breast Feeding | Childbearing Potential Contraceptive methods Absent
Item
women who are pregnant (positive pregnancy test) or breast-feeding, or absence of contraception in a woman who is able to become pregnant.
boolean
C0032961 (UMLS CUI [1])
C0240802 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
C3831118 (UMLS CUI [4,1])
C0700589 (UMLS CUI [4,2])
C0332197 (UMLS CUI [4,3])
Tooth problem | Tooth Infection | Infection jaw | Exposure Buccal Jaw | Osteonecrosis of Jaw Requirement Operative Surgical Procedure
Item
patient with evolutionary dental problems, including dental infection or infection of the jaw,intrabuccal exposure of jawbone, and history or current diagnosis of osteonecrosis of the jaw,requiring a fast chirurgical care.
boolean
C0576962 (UMLS CUI [1])
C0877046 (UMLS CUI [2])
C1400570 (UMLS CUI [3])
C0332157 (UMLS CUI [4,1])
C0442010 (UMLS CUI [4,2])
C0022359 (UMLS CUI [4,3])
C2711248 (UMLS CUI [5,1])
C1514873 (UMLS CUI [5,2])
C0543467 (UMLS CUI [5,3])
Intravenous bisphosphonates | Diphosphonates Oral
Item
prior treatment with bisphosphonates (either iv or oral).
boolean
C1955566 (UMLS CUI [1])
C0012544 (UMLS CUI [2,1])
C1527415 (UMLS CUI [2,2])
Bone Disease Severe | Severe osteoporosis | Events Skeletal Multiple
Item
history of severe bone disease (severe osteoporosis with multiple skeletal-related events).
boolean
C0005940 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C1859443 (UMLS CUI [2])
C0441471 (UMLS CUI [3,1])
C0521324 (UMLS CUI [3,2])
C0439064 (UMLS CUI [3,3])