Locally advanced breast cancer
Item
locally advanced breast cancer diagnosed by guided core biopsy
boolean
C3495949 (UMLS CUI [1])
Tumor size | Positive Lymph Node | Needle biopsy Required
Item
t > 2 cm (any n), or any t and node positive (needle biopsy is required)
boolean
C0475440 (UMLS CUI [1])
C0746319 (UMLS CUI [2])
C0005560 (UMLS CUI [3,1])
C1514873 (UMLS CUI [3,2])
Disease Without Neoplasm Metastasis | Computed Tomography | Bone scintigraphy
Item
non-metastatic disease assessed by computed tomography and bone scintigraphy
boolean
C0012634 (UMLS CUI [1,1])
C0332288 (UMLS CUI [1,2])
C0027627 (UMLS CUI [1,3])
C0040405 (UMLS CUI [2])
C3889015 (UMLS CUI [3])
Histopathologic Grade | Ki67 Measurement
Item
histological grade 2 and ki67 > 15% or
boolean
C0919553 (UMLS CUI [1])
C4049944 (UMLS CUI [2])
Histopathologic Grade
Item
histological grade 3 or
boolean
C0919553 (UMLS CUI [1])
Triple-Negative Breast Cancer
Item
any triple negative (tn) or
boolean
C2348819 (UMLS CUI [1])
Inflammatory Breast Carcinoma
Item
inflammatory breast cancer (ibc)
boolean
C0278601 (UMLS CUI [1])
Left ventricular ejection fraction Normal
Item
normal left ventricular ejection fraction (lvef)
boolean
C0428772 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
Disease HER2 Negative
Item
her2-negative disease
boolean
C0012634 (UMLS CUI [1,1])
C2348908 (UMLS CUI [1,2])
Cancer Other | Exception Curative treatment Skin carcinoma | Exception Curative treatment Carcinoma in situ of uterine cervix | Exception Curative treatment Ductal carcinoma in situ of breast | Exception Curative treatment Lobular carcinoma in situ of breast
Item
another malignancy within the last 5 years (except curatively treated skin carcinoma, in situ cervix carcinoma, in situ ductal carcinoma of the breast, or in situ lobular carcinoma of the breast)
boolean
C1707251 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C1273390 (UMLS CUI [2,2])
C0699893 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C1273390 (UMLS CUI [3,2])
C0851140 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C1273390 (UMLS CUI [4,2])
C0007124 (UMLS CUI [4,3])
C1705847 (UMLS CUI [5,1])
C1273390 (UMLS CUI [5,2])
C0279563 (UMLS CUI [5,3])
Comorbidity Clinical Significance | Cardiovascular Diseases | Chronic Obstructive Airway Disease | Kidney Failure | Liver Failure | Mental disorders
Item
clinically significant comorbidities as cardiovascular diseases, chronic obstructive pulmonary disease (copd), renal or liver failure, psychiatric disorders
boolean
C0009488 (UMLS CUI [1,1])
C2826293 (UMLS CUI [1,2])
C0007222 (UMLS CUI [2])
C0024117 (UMLS CUI [3])
C0035078 (UMLS CUI [4])
C0085605 (UMLS CUI [5])
C0004936 (UMLS CUI [6])
Left ventricular ejection fraction decreased
Item
lvef value below institutional limits of normal
boolean
C1096403 (UMLS CUI [1])
Lobular Carcinoma Histology predominant
Item
predominant lobular carcinoma histology
boolean
C0206692 (UMLS CUI [1,1])
C0344441 (UMLS CUI [1,2])
C1542147 (UMLS CUI [1,3])
Histopathologic Grade
Item
grade 1 tumors
boolean
C0919553 (UMLS CUI [1])
Distant metastasis | Distant metastasis Suspected
Item
detected or suspicious distant metastasis
boolean
C1269798 (UMLS CUI [1])
C1269798 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
Neutrophil count | Platelet Count measurement | Hemoglobin measurement | Aspartate Aminotransferase Increased | SERUM TOTAL BILIRUBIN ELEVATED | Alkaline phosphatase raised
Item
neutrophils less than 1,500/µl, platelets less than 100,000/µl, hemoglobin less than 10 g/dl, ast more than 2.5x upper limit of normal (uln), total bilirubin more than uln, alkaline phosphatase more than 1.5x uln
boolean
C0200633 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C0518015 (UMLS CUI [3])
C0151904 (UMLS CUI [4])
C0595866 (UMLS CUI [5])
C0151849 (UMLS CUI [6])
Gender
Item
male sex
boolean
C0079399 (UMLS CUI [1])
HER2-positive carcinoma of breast
Item
her2-positive breast cancer
boolean
C1960398 (UMLS CUI [1])