Squamous cell carcinoma of esophagus
Item
patients must have been histologically proven esophageal carcinoma (squamous cell carcinoma).
boolean
C0279626 (UMLS CUI [1])
Locally Advanced Malignant Neoplasm TNM clinical staging
Item
the tumor had to be locally advanced (stage t2-3/n0, t1-3/n+, if technically resectable with curative intent).
boolean
C0677984 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
Age
Item
patients must be 20 years of age.
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
patients must have an ecog performance status score 2.
boolean
C1520224 (UMLS CUI [1])
Life Expectancy
Item
patients must have a life expectancy of at least 12 weeks.
boolean
C0023671 (UMLS CUI [1])
Patient Available Therapeutic procedure | Patients Available Follow-up
Item
patients must be accessible for treatment and follow-up at least for one year.
boolean
C0030705 (UMLS CUI [1,1])
C0470187 (UMLS CUI [1,2])
C0087111 (UMLS CUI [1,3])
C0030705 (UMLS CUI [2,1])
C0470187 (UMLS CUI [2,2])
C3274571 (UMLS CUI [2,3])
Informed Consent
Item
patients must sign the informed consent form.
boolean
C0021430 (UMLS CUI [1])
Hemoglobin measurement | Neutrophil count | Platelet Count measurement | Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Alkaline phosphatase measurement | Creatinine measurement, serum | Estimation of creatinine clearance by Cockcroft-Gault formula
Item
patient must have:hemoglobin level 9 g/dl; neutrophil count 1,500/mm3; platelets count 100,000/mm3; serum bilirubin level 1.0 uln; serum transaminase (got, gpt) levels 2.0 uln; serum alkaline phosphatase levels 2.0 uln; serum creatinine level 1.5 mg/dl or creatinine clearance rate(crcl)60 ml/min for the institution (calculated by the cockcroft- gault equation).
boolean
C0518015 (UMLS CUI [1])
C0200633 (UMLS CUI [2])
C0032181 (UMLS CUI [3])
C1278039 (UMLS CUI [4])
C0201899 (UMLS CUI [5])
C0201836 (UMLS CUI [6])
C0201850 (UMLS CUI [7])
C0201976 (UMLS CUI [8])
C2711451 (UMLS CUI [9])
Therapeutic radiology procedure Esophageal carcinoma | Chemotherapy Esophageal carcinoma | Cancer treatment Esophageal carcinoma
Item
patient who are receiving or had received concurrent radiotherapy, chemotherapy or other anticancer treatment for esophageal carcinoma.
boolean
C1522449 (UMLS CUI [1,1])
C0152018 (UMLS CUI [1,2])
C0392920 (UMLS CUI [2,1])
C0152018 (UMLS CUI [2,2])
C0920425 (UMLS CUI [3,1])
C0152018 (UMLS CUI [3,2])
Severe allergy Pharmaceutical Preparations | Severe allergy Polysorbate 80
Item
patients with known history of severe hypersensitivity reactions to any medicine or to drugs formulated with polysorbate 80.
boolean
C2945656 (UMLS CUI [1,1])
C0013227 (UMLS CUI [1,2])
C2945656 (UMLS CUI [2,1])
C0032601 (UMLS CUI [2,2])
Major surgery | Exception Port-A-Cath | Exception Jejunostomy feeding
Item
major surgery within two weeks prior to entering the study, excluding port-a insertion or feeding jejunostomy surgery.
boolean
C0679637 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C3495140 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0192715 (UMLS CUI [3,2])
CNS metastases | Suspicion CNS metastases
Item
patients with cns metastasis, including clinical suspicion.
boolean
C0686377 (UMLS CUI [1])
C0242114 (UMLS CUI [2,1])
C0686377 (UMLS CUI [2,2])
Peripheral Neuropathy CTCAE Grades
Item
patients with clinically detectable peripheral neuropathy 2 on the ctc criteria.
boolean
C0031117 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
Mental state unfit Clinical Trial
Item
mental statuses of patients are not fit for clinical trial.
boolean
C0278060 (UMLS CUI [1,1])
C3841806 (UMLS CUI [1,2])
C0008976 (UMLS CUI [1,3])
Females & males of reproductive potential | Exception Contraceptive methods
Item
fertile men and women unless using a reliable and appropriate contraceptive method.
boolean
C4034483 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
Pregnancy | Breast Feeding | Gender considering Pregnancy | Possible pregnancy | Contraceptive methods Absent
Item
patients with pregnancy or lactating, women considering pregnancy, possible pregnancy that without using effective contraception.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0079399 (UMLS CUI [3,1])
C0750591 (UMLS CUI [3,2])
C0032961 (UMLS CUI [3,3])
C0425965 (UMLS CUI [4])
C0700589 (UMLS CUI [5,1])
C0332197 (UMLS CUI [5,2])
Comorbidity Serious | Heart Disease | Congestive heart failure | Angina Pectoris | Cardiac Arrhythmia | Cardiomyopathy | Communicable Disease Uncontrolled | Body fluid retention | Pleural effusion | Ascites | Pericardial effusion | Edema Treatment required for | Cancer Other | Exception Curative treatment Skin carcinoma | Exception Curative treatment Carcinoma in situ of esophagus
Item
patients who have serious concomitant illness that might be aggravated by chemotherapy, as below included:active cardiac disease (e.g. congestive heart failure, angina, arrhythmia, acute myocardial disease or other types of heart disease requiring treatment) within 6 months period preceding entry into the study; uncontrolled infection (e.g. active infection that uncontrolled for 2 weeks under antibiotic therapy); retention of body fluid (e.g. pleural effusion, ascites, pericardial effusion, and edema needing treatment); history of other than esophageal cancer, except curatively treated non-melanoma skin cancer or in situ carcinoma of the esophagus; and other conditions which will be judged by physician's discretion.
boolean
C0009488 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0018799 (UMLS CUI [2])
C0018802 (UMLS CUI [3])
C0002962 (UMLS CUI [4])
C0003811 (UMLS CUI [5])
C0878544 (UMLS CUI [6])
C0009450 (UMLS CUI [7,1])
C0205318 (UMLS CUI [7,2])
C0268000 (UMLS CUI [8])
C0032227 (UMLS CUI [9])
C0003962 (UMLS CUI [10])
C0031039 (UMLS CUI [11])
C0013604 (UMLS CUI [12,1])
C0332121 (UMLS CUI [12,2])
C1707251 (UMLS CUI [13])
C1705847 (UMLS CUI [14,1])
C1273390 (UMLS CUI [14,2])
C0699893 (UMLS CUI [14,3])
C1705847 (UMLS CUI [15,1])
C1273390 (UMLS CUI [15,2])
C0154059 (UMLS CUI [15,3])