Liver carcinoma | Measurable lesion Linear Quantity | CT scan | MRI
Item
histological or cytological diagnosis or meet the aasld criteria for diagnosis of hcc and at least one uni-dimensional lesion measurable according to recist criteria by ct-scan or mri
boolean
C2239176 (UMLS CUI [1])
C1513041 (UMLS CUI [2,1])
C0205132 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0040405 (UMLS CUI [3])
C0024485 (UMLS CUI [4])
Adult | Age | Life Expectancy
Item
adult over 18 years old and estimated life expectancy over 3 months
boolean
C0001675 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0023671 (UMLS CUI [3])
Liver carcinoma Advanced BCLC Stage | Portal Vein Thrombosis | Portal Vein Thrombosis Absent | Ineligibility Excision | Ineligibility Transplantation of liver | Ineligibility Radiofrequency Ablation | Liver carcinoma Progression | Recurrent Liver Carcinoma | Status post Operative Surgical Procedure | Status post Therapy Locoregional
Item
patient with advanced hcc according to bclc staging system (stage c) with or without portal vein thrombosis, not eligible for surgical resection, liver transplantation nor radiofrequency ablation or patient with progression or recurrence of hcc after surgical or locoregional treatment not eligible for surgical resection, liver transplantation nor radiofrequency ablation.
boolean
C2239176 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C3899974 (UMLS CUI [1,3])
C0155773 (UMLS CUI [2])
C0155773 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C1512714 (UMLS CUI [4,1])
C0728940 (UMLS CUI [4,2])
C1512714 (UMLS CUI [5,1])
C0023911 (UMLS CUI [5,2])
C1512714 (UMLS CUI [6,1])
C0850292 (UMLS CUI [6,2])
C2239176 (UMLS CUI [7,1])
C0242656 (UMLS CUI [7,2])
C0854794 (UMLS CUI [8])
C0231290 (UMLS CUI [9,1])
C0543467 (UMLS CUI [9,2])
C0231290 (UMLS CUI [10,1])
C0087111 (UMLS CUI [10,2])
C1947913 (UMLS CUI [10,3])
ECOG performance status
Item
ecog performance status under or equals 1
boolean
C1520224 (UMLS CUI [1])
Hematologic function | Hemoglobin measurement | Absolute neutrophil count | Platelet Count measurement
Item
adequate haematological function: hb over or equals 9g/100ml, absolute neutrophil count over or equals 1 500/mm3, platelet count over or equals 50 000/mm3
boolean
C0221130 (UMLS CUI [1])
C0518015 (UMLS CUI [2])
C0948762 (UMLS CUI [3])
C0032181 (UMLS CUI [4])
Renal function | Creatinine measurement, serum
Item
adequate renal function; serum creatinine under 150μmol/l
boolean
C0232804 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | International Normalized Ratio
Item
bilirubin under or equals 50 µmol/l, ast or alt uner or equals 5 x uln, inr under or equals 1.5
boolean
C1278039 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
C0525032 (UMLS CUI [4])
Liver Cirrhosis Child-Pugh Clinical Classification
Item
liver cirrhosis child pugh a - b7
boolean
C0023890 (UMLS CUI [1,1])
C4050412 (UMLS CUI [1,2])
Informed Consent
Item
written informed consent
boolean
C0021430 (UMLS CUI [1])
Cancer Other | Exception Basal cell carcinoma | Exception Superficial carcinoma of urinary bladder
Item
another primary tumour, with the exception of conventional basal cell carcinoma or superficial bladder neoplasia
boolean
C1707251 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C1336527 (UMLS CUI [3,2])
Neoplasm Metastasis Extrahepatic
Item
extrahepatic metastasis
boolean
C0027627 (UMLS CUI [1,1])
C1517058 (UMLS CUI [1,2])
Prior Therapy Liver carcinoma Advanced
Item
advanced hcc previously treated
boolean
C1514463 (UMLS CUI [1,1])
C2239176 (UMLS CUI [1,2])
C0205179 (UMLS CUI [1,3])
Liver disease Advanced Child-Pugh Clinical Classification | Gastrointestinal Hemorrhage | Encephalopathy | Ascites Unresponsive to Diuretic therapy | Pregnancy | Breast Feeding
Item
advanced liver disease with child-pugh score over 7 or active gastrointestinal bleeding or encephalopathy or ascites refractory to diuretic therapy women who are pregnant or breast feeding
boolean
C0023895 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C4050412 (UMLS CUI [1,3])
C0017181 (UMLS CUI [2])
C0085584 (UMLS CUI [3])
C0003962 (UMLS CUI [4,1])
C0205269 (UMLS CUI [4,2])
C0948575 (UMLS CUI [4,3])
C0032961 (UMLS CUI [5])
C0006147 (UMLS CUI [6])
Contrast media allergy
Item
allergy to contrast media
boolean
C0570562 (UMLS CUI [1])
Medical contraindication Arterial catheterization Hepatic | Peripheral Vascular Disease Severe Excludes Catheterization
Item
contraindication to hepatic artery catheterisation, such as severe peripheral vascular disease precluding catheterisation
boolean
C1301624 (UMLS CUI [1,1])
C0007431 (UMLS CUI [1,2])
C0205054 (UMLS CUI [1,3])
C0085096 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C0332196 (UMLS CUI [2,3])
C0007430 (UMLS CUI [2,4])
Mental disorder Impact Informed Consent | Other medical condition Impact Informed Consent
Item
psychiatric or other disorder likely to impact on informed consent
boolean
C0004936 (UMLS CUI [1,1])
C4049986 (UMLS CUI [1,2])
C0021430 (UMLS CUI [1,3])
C3843040 (UMLS CUI [2,1])
C4049986 (UMLS CUI [2,2])
C0021430 (UMLS CUI [2,3])
Treatment Compliance Unable | Treatment Compliance Unwilling
Item
patient unable and/or unwilling to comply with treatment and study instructions
boolean
C4319828 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
C4319828 (UMLS CUI [2,1])
C0558080 (UMLS CUI [2,2])
Lacking Able to swallow Oral Medication
Item
patient unable to swallow oral medications
boolean
C0332268 (UMLS CUI [1,1])
C2712086 (UMLS CUI [1,2])
C0175795 (UMLS CUI [1,3])