Gender | Invasive carcinoma of breast | DCIS
Item
women with a history of invasive breast cancer or dcis
boolean
C0079399 (UMLS CUI [1])
C0853879 (UMLS CUI [2])
C0007124 (UMLS CUI [3])
Aromatase Inhibitors | Tamoxifen
Item
currently taking aromatase inhibitors or tamoxifen
boolean
C0593802 (UMLS CUI [1])
C0039286 (UMLS CUI [2])
Hormone replacement therapy Absent
Item
not receiving hormone replacement therapy for minimum of one month
boolean
C0282402 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Age
Item
age 18 years or older
boolean
C0001779 (UMLS CUI [1])
Hot flushes times per week
Item
self-reported hot flashes greater than seven times per week
boolean
C0600142 (UMLS CUI [1,1])
C0456698 (UMLS CUI [1,2])
Hot flushes Duration
Item
self-reported hot flashes for at least one month
boolean
C0600142 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
Other treatment Hot flushes | Estrogens | Progestins | Androgens | gabapentin | Antidepressive Agents | venlafaxine | Paroxetine | Citalopram | Sertraline
Item
receiving any other treatment for hot flashes within the past month, including estrogens, progestins, androgens, gabapentin, or antidepressants such as venlafaxine, paroxetine, citalopram , sertraline, etc.
boolean
C2015819 (UMLS CUI [1,1])
C0600142 (UMLS CUI [1,2])
C0014939 (UMLS CUI [2])
C0033306 (UMLS CUI [3])
C0002844 (UMLS CUI [4])
C0060926 (UMLS CUI [5])
C0003289 (UMLS CUI [6])
C0078569 (UMLS CUI [7])
C0070122 (UMLS CUI [8])
C0008845 (UMLS CUI [9])
C0074393 (UMLS CUI [10])
Clonidine | Solifenacin
Item
current use of clonidine or solifenacin. (if patients have been off of these for one month, then they are eligible)
boolean
C0009014 (UMLS CUI [1])
C1099677 (UMLS CUI [2])
Renal Insufficiency Severe | Hepatic impairment Moderate | Hepatic impairment Severe
Item
history of severe renal or moderate or severe hepatic impairment, as indicated by physical exam and medical record
boolean
C1565489 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0948807 (UMLS CUI [2,1])
C0205081 (UMLS CUI [2,2])
C0948807 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
Chemotherapy | Therapeutic radiology procedure | Chemotherapy Planned | Therapeutic radiology procedure Planned
Item
concurrent or planned chemotherapy or radiotherapy (within next 3 months)
boolean
C0392920 (UMLS CUI [1])
C1522449 (UMLS CUI [2])
C0392920 (UMLS CUI [3,1])
C1301732 (UMLS CUI [3,2])
C1522449 (UMLS CUI [4,1])
C1301732 (UMLS CUI [4,2])
Monoamine Oxidase Inhibitors | Levodopa | Piribedil | Barbiturates | moxifloxacin | Pimozide | Antihypertensive therapy
Item
currently receiving monoamine oxidase inhibitors, l-dopa, piribedil, barbiturates, moxifloxacin, pimozide, or antihypertensive treatment
boolean
C0026457 (UMLS CUI [1])
C0023570 (UMLS CUI [2])
C0031979 (UMLS CUI [3])
C0004745 (UMLS CUI [4])
C0536495 (UMLS CUI [5])
C0031935 (UMLS CUI [6])
C0585941 (UMLS CUI [7])
CYP3A4 Inducers | Aminoglutethimide | Carbamazepine | Dexamethasone | efavirenz | Ethosuximide | Griseofulvin | modafinil | Nafcillin | Nevirapine | oxcarbazepine | Phenobarbital | Phenylbutazone | Phenytoin | Primidone | Rifabutin | Rifampin | rifapentine | Hypericum perforatum | Sulfamethazine | Sulfinpyrazone | troglitazone | CYP3A4 Inhibitors Strong | Clarithromycin | Chloramphenicol | Erythromycin | Imatinib mesylate | Indinavir Sulfate | Itraconazole | Ketoconazole | nefazodone | Nelfinavir Mesylate | Ritonavir | telithromycin | Troleandomycin
Item
currently using cyp3a4 inducers (i.e., aminoglutethimide, carbamazepine, dexamethasone, efavirenz, ethosuximide, griseofulvin, modafinil, nafcillin, nevirapine, oxcarbazepine, phenobarbital, phenylbutazone, phenytoin, primidone, rifabutin, rifampin, rifapentine, st. john's wort, sulfadimidine, sulfinpyrazone, troglitazone) or potent cyp3a4 inhibitors (i.e., clarithromycin, chloramphenicol, erythromycin, imatinib mesylate, indinavir sulfate, itraconazole, ketoconazole, nefazodone, nelfinavir mesylate, ritonavir, telithromycin, troleandomycin).
boolean
C3850041 (UMLS CUI [1])
C0002555 (UMLS CUI [2])
C0006949 (UMLS CUI [3])
C0011777 (UMLS CUI [4])
C0674428 (UMLS CUI [5])
C0015043 (UMLS CUI [6])
C0018242 (UMLS CUI [7])
C0066677 (UMLS CUI [8])
C0027324 (UMLS CUI [9])
C0132326 (UMLS CUI [10])
C0069751 (UMLS CUI [11])
C0031412 (UMLS CUI [12])
C0031463 (UMLS CUI [13])
C0031507 (UMLS CUI [14])
C0033148 (UMLS CUI [15])
C0140575 (UMLS CUI [16])
C0035608 (UMLS CUI [17])
C0073372 (UMLS CUI [18])
C0936242 (UMLS CUI [19])
C0038686 (UMLS CUI [20])
C0038742 (UMLS CUI [21])
C0245514 (UMLS CUI [22])
C3850053 (UMLS CUI [23,1])
C0442821 (UMLS CUI [23,2])
C0055856 (UMLS CUI [24])
C0008168 (UMLS CUI [25])
C0014806 (UMLS CUI [26])
C0939537 (UMLS CUI [27])
C0700483 (UMLS CUI [28])
C0064113 (UMLS CUI [29])
C0022625 (UMLS CUI [30])
C0068485 (UMLS CUI [31])
C0886530 (UMLS CUI [32])
C0292818 (UMLS CUI [33])
C0907410 (UMLS CUI [34])
C0041165 (UMLS CUI [35])
Angle Closure Glaucoma Uncontrolled | Angle Closure Glaucoma Poorly controlled | Urinary Retention | Gastric retention
Item
uncontrolled or poorly controlled closed-angle glaucoma, urinary retention, gastric retention (evaluated from history & physical exam and medical record)
boolean
C0017605 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0017605 (UMLS CUI [2,1])
C3853134 (UMLS CUI [2,2])
C0080274 (UMLS CUI [3])
C0585136 (UMLS CUI [4])
Hypotension | Systolic Pressure
Item
hypotension (systolic bp < 80)
boolean
C0020649 (UMLS CUI [1])
C0871470 (UMLS CUI [2])
Coronary artery insufficiency Severe | Abnormal cardiac conduction | Recent myocardial infarction | Cerebrovascular Disorders | Syncope
Item
severe coronary insufficiency, conduction disturbances, recent myocardial infarction (within past 3 months), cerebrovascular disease, syncope (evaluated from history &
boolean
C0542052 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0232219 (UMLS CUI [2])
C1998297 (UMLS CUI [3])
C0007820 (UMLS CUI [4])
C0039070 (UMLS CUI [5])
ID.16
Item
physical and medical record)
boolean
Clonidine allergy | Adverse reactions Clonidine | Hypersensitivity Solifenacin | Adverse reactions Solifenacin
Item
history of allergy or adverse reactions to clonidine or solifenacin
boolean
C0570975 (UMLS CUI [1])
C0559546 (UMLS CUI [2,1])
C0009014 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C1099677 (UMLS CUI [3,2])
C0559546 (UMLS CUI [4,1])
C1099677 (UMLS CUI [4,2])
ECOG performance status
Item
ecog status >2 (in bed more than 50% of day)
boolean
C1520224 (UMLS CUI [1])