Age
Item
aged form 18 years to 75 years old
boolean
C0001779 (UMLS CUI [1])
Knee Osteoarthritis ACR Criteria
Item
diagnosed with osteoarthritis of the knee according to the american college of rheumatology
boolean
C0409959 (UMLS CUI [1,1])
C3273747 (UMLS CUI [1,2])
Functional Status New York Heart Association Classification
Item
functional capacity class of ⅰ-ⅲ
boolean
C0598463 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Angina, Unstable
Item
unstable angina
boolean
C0002965 (UMLS CUI [1])
Myocardial Infarction
Item
history of myocardial infarction within the last 6 months
boolean
C0027051 (UMLS CUI [1])
Cerebrovascular accident
Item
stroke in the 6 months before screening
boolean
C0038454 (UMLS CUI [1])
Congestive heart failure New York Heart Association Classification
Item
new york heart association class ⅲ-ⅳ congestive heart-failure
boolean
C0018802 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Systolic Pressure | Diastolic blood pressure
Item
systolic blood pressure＞180mmhg,and/or diastolic blood pressure＞100mmhg
boolean
C0871470 (UMLS CUI [1])
C0428883 (UMLS CUI [2])
Peptic Ulcer
Item
peptic ulcer
boolean
C0030920 (UMLS CUI [1])
Medical contraindication Non-Steroidal Anti-Inflammatory Agents
Item
known contraindications to non-steroidal anti-inflammatory drug（nsaid）
boolean
C1301624 (UMLS CUI [1,1])
C0003211 (UMLS CUI [1,2])
Aspirin Recent
Item
received aspirin within 3 days of baseline visit
boolean
C0004057 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Aspirin Dosage mg/d
Item
aspirin dosage>150mg/d
boolean
C0004057 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0439422 (UMLS CUI [1,3])
Allergy to sulfonamides | Hypersensitivity cox-2 Inhibitors
Item
known to be allergic to sulfa and cox-2 inhibitors
boolean
C0038757 (UMLS CUI [1])
C0020517 (UMLS CUI [2,1])
C1257954 (UMLS CUI [2,2])
Pregnancy | Breast Feeding
Item
pregnancy or lactation
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Aspartate aminotransferase increased | Alanine aminotransferase increased
Item
glutamic-oxaloacetic transaminase and/or glutamic-pyruvic transaminase＞2 times upper limit of normal
boolean
C0151904 (UMLS CUI [1])
C0151905 (UMLS CUI [2])
Blood urea nitrogen increased
Item
blood urine nitrogen＞1.5 times upper limit of normal
boolean
C0151539 (UMLS CUI [1])