Age
Item
age 18 to 80 years
boolean
C0001779 (UMLS CUI [1])
Knee Osteoarthritis Symptomatic ACR Criteria
Item
symptomatic knee oa as defined by the american college of rheumatology criteria
boolean
C0409959 (UMLS CUI [1,1])
C0231220 (UMLS CUI [1,2])
C3273747 (UMLS CUI [1,3])
X-Ray Computed Tomography Kellgren-Lawrence score
Item
kellgren-lawrence grade i, ii or iii on prior x-rays (take within 6 months of screening visit)
boolean
C0040405 (UMLS CUI [1,1])
C3177117 (UMLS CUI [1,2])
Knee pain Visual Analog Pain Scale
Item
knee pain score >40 mm on a 100 mm visual analogue scale for > 15 days in the last month
boolean
C0231749 (UMLS CUI [1,1])
C0042815 (UMLS CUI [1,2])
NSAIDs Dose Stable
Item
nsaids permitted if the dose has been stable for at least one month prior to baseline and stays stable during the study
boolean
C0003211 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
Euflexxa Recommended
Item
have been recommended for euflexxa treatment by physician
boolean
C1637315 (UMLS CUI [1,1])
C0034866 (UMLS CUI [1,2])
Knee effusion Clinical examination | Knee effusion Imaging
Item
knee effusion based on clinical exam or imaging
boolean
C0343166 (UMLS CUI [1,1])
C1456356 (UMLS CUI [1,2])
C0343166 (UMLS CUI [2,1])
C0011923 (UMLS CUI [2,2])
Medical contraindication MRI | Pregnancy | Metal foreign body in eye region | Vascular clip | Pacemakers
Item
any contraindication to mri (pregnancy, metallic fragments in the eyes, vascular clips, pacemakers etc)
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0032961 (UMLS CUI [2])
C0562528 (UMLS CUI [3])
C0179992 (UMLS CUI [4])
C0810633 (UMLS CUI [5])
Knee Replacement
Item
history of knee replacement
boolean
C0086511 (UMLS CUI [1])
Hypersensitivity Euflexxa Component
Item
known sensitivity or allergy to any component of euflexxa
boolean
C0020517 (UMLS CUI [1,1])
C1637315 (UMLS CUI [1,2])
C1705248 (UMLS CUI [1,3])
Arthritis
Item
inflammatory arthritis
boolean
C0003864 (UMLS CUI [1])
Viscosupplementation
Item
previously received viscosupplementation therapy within 12 months of study enrollment
boolean
C2350507 (UMLS CUI [1])
Intraarticular steroid injection Target Joint
Item
intra-articular injection of corticosteroid to study joint within the past 3 months
boolean
C2064783 (UMLS CUI [1,1])
C1521840 (UMLS CUI [1,2])
C0022417 (UMLS CUI [1,3])
Arthroscopic Surgical Procedure Target Joint | Open Surgical Procedure Target Joint | Operative Surgical Procedure Planned Target Joint
Item
arthroscopic or open surgery within the previous 12 months or planned surgery to the study joint
boolean
C0750934 (UMLS CUI [1,1])
C1521840 (UMLS CUI [1,2])
C0022417 (UMLS CUI [1,3])
C4283938 (UMLS CUI [2,1])
C1521840 (UMLS CUI [2,2])
C0022417 (UMLS CUI [2,3])
C0543467 (UMLS CUI [3,1])
C1301732 (UMLS CUI [3,2])
C1521840 (UMLS CUI [3,3])
C0022417 (UMLS CUI [3,4])
Adrenal Cortex Hormones Oral | Adrenal Cortex Hormones Parenteral
Item
concomitant medications of oral/parenteral corticosteroids
boolean
C0001617 (UMLS CUI [1,1])
C1527415 (UMLS CUI [1,2])
C0001617 (UMLS CUI [2,1])
C1518896 (UMLS CUI [2,2])
Obesity, Morbid | Body mass index
Item
morbid obesity defined as body mass index (bmi) >40 kg/m2
boolean
C0028756 (UMLS CUI [1])
C1305855 (UMLS CUI [2])
Malignant Neoplasms | Sepsis | Trauma Target Joint
Item
active malignancy; an active systemic infection; recent high impact or high energy trauma (clinically defined) to the study joint
boolean
C0006826 (UMLS CUI [1])
C0243026 (UMLS CUI [2])
C3714660 (UMLS CUI [3,1])
C1521840 (UMLS CUI [3,2])
C0022417 (UMLS CUI [3,3])
Knee effusion Large Clinical examination | Knee effusion Large Imaging
Item
large knee effusion based on clinical exam or imaging
boolean
C0343166 (UMLS CUI [1,1])
C0549177 (UMLS CUI [1,2])
C1456356 (UMLS CUI [1,3])
C0343166 (UMLS CUI [2,1])
C0549177 (UMLS CUI [2,2])
C0011923 (UMLS CUI [2,3])