Chronic heart failure | Inclusion criteria All Fulfill
Item
1. chronic heart failure will be defined by the following criteria (all must be included):
boolean
C0264716 (UMLS CUI [1])
C1512693 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
C1550543 (UMLS CUI [2,3])
Heart failure Duration
Item
diagnosis of hf known for at least 6 months
boolean
C0018801 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
Medical History Hospitalization Heart Decompensation | Patient need for Parenteral therapy Congestion | X-ray of both lower extremities | Edema of lower extremity
Item
medical history of hospitalization for cardiac decompensation with need for parenteral therapy for congestion - x-ray findings or swelling of lower extremities
boolean
C0262926 (UMLS CUI [1,1])
C0019993 (UMLS CUI [1,2])
C1961112 (UMLS CUI [1,3])
C0686904 (UMLS CUI [2,1])
C0259961 (UMLS CUI [2,2])
C0700148 (UMLS CUI [2,3])
C3861120 (UMLS CUI [3])
C0239340 (UMLS CUI [4])
Pharmacotherapy Stable
Item
stable drug therapy at least 1 month
boolean
C0013216 (UMLS CUI [1,1])
C0205360 (UMLS CUI [1,2])
Diuretics | Thiazide | Furosemide
Item
treatment with diuretics (thiazide or furosemide)
boolean
C0012798 (UMLS CUI [1])
C0012802 (UMLS CUI [2])
C0016860 (UMLS CUI [3])
Left ventricular ejection fraction
Item
lvef below 50%
boolean
C0428772 (UMLS CUI [1])
Diabetes Mellitus
Item
2. the presence of diabetes will be defined by:
boolean
C0011849 (UMLS CUI [1])
Medical History Non-Insulin-Dependent Diabetes Mellitus | Therapy Non-Insulin-Dependent Diabetes Mellitus
Item
diagnosis and treatment of type 2 diabetes in the medical history
boolean
C0262926 (UMLS CUI [1,1])
C0011860 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C0011860 (UMLS CUI [2,2])
Blood specimen
Item
screening blood sample:
boolean
C0178913 (UMLS CUI [1])
Hemoglobin A1c measurement | Fasting glucose measurement Venous plasma
Item
the value of hba1c(according to ifcc)≥ 4.8% + fasting glucose ≥ 7.0 mmol /
boolean
C0474680 (UMLS CUI [1])
C0202045 (UMLS CUI [2,1])
C3838734 (UMLS CUI [2,2])
ID.11
Item
l in venous plasma or
boolean
Hemoglobin A1c measurement | Random blood glucose measurement Venous plasma
Item
the value of hba1c ≥ 4.8%(according to ifcc) + random blood glucose ≥ 11.1 mmol/l in venous plasma
boolean
C0474680 (UMLS CUI [1])
C0428567 (UMLS CUI [2,1])
C3838734 (UMLS CUI [2,2])
Oral Glucose Tolerance Test | Blood glucose measurement
Item
or ogtt - blood glucose level at 120 min ≥ 11.1 mmol/l ogtt is indicated just in case of positivity of one of the criteria (fasting glucose + hba1c or hba1c + random blood glucose)
boolean
C0029161 (UMLS CUI [1])
C0392201 (UMLS CUI [2])
Diet therapy Diabetes Mellitus
Item
treatment of diabetes - by diet only
boolean
C0012159 (UMLS CUI [1,1])
C0011849 (UMLS CUI [1,2])
Age
Item
women and men aged 40-70 years
boolean
C0001779 (UMLS CUI [1])
Body mass index
Item
body mass index (kg/m2) in the range of 20-35
boolean
C1305855 (UMLS CUI [1])
Hemoglobin A1c measurement
Item
the range of hba1c between 4-6,5% ifcc
boolean
C0474680 (UMLS CUI [1])
Informed Consent
Item
signed informed consent
boolean
C0021430 (UMLS CUI [1])
Intervention cardiac Affecting Cardiac function | Revascularization | Percutaneous Coronary Intervention | Cardiac Surgery procedures | Implantation of cardiac pacemaker | Radiofrequency ablation
Item
1. the planned cardiac intervention during the study that affect the function of the heart (revascularization including pci, heart surgery, implantation of pacemaker, rf ablation; urgent candidate for ots
boolean
C0184661 (UMLS CUI [1,1])
C0018787 (UMLS CUI [1,2])
C0392760 (UMLS CUI [1,3])
C0232164 (UMLS CUI [1,4])
C0581603 (UMLS CUI [2])
C1532338 (UMLS CUI [3])
C0018821 (UMLS CUI [4])
C0189842 (UMLS CUI [5])
C0850292 (UMLS CUI [6])
Metabolic Disease | Diabetes Mellitus, Insulin-Dependent | Thyroid Disease Decompensated
Item
2. metabolic disease, including: 1 type diabetes, decompensated thyreopathy (note: patients with hypothyroidism and stable substitution (the last 3 months) of normal tsh levels may participate in the study
boolean
C0025517 (UMLS CUI [1])
C0011854 (UMLS CUI [2])
C0040128 (UMLS CUI [3,1])
C0205434 (UMLS CUI [3,2])
Insulin regime Recent
Item
3. treatment with insulin or pad one month before the recruitment(patients who were temporarily treated with insulin during hospitalization may participate in the study)
boolean
C0557978 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Pregnancy | Serum pregnancy test (B-HCG) Positive | Breast Feeding | Trying to conceive
Item
4. pregnancy (positive β-hcg test), breast feeding, trying to become pregnant
boolean
C0032961 (UMLS CUI [1])
C0430060 (UMLS CUI [2,1])
C1514241 (UMLS CUI [2,2])
C0006147 (UMLS CUI [3])
C0420843 (UMLS CUI [4])
Anemia | Hemoglobin measurement
Item
5. clinically significant anemia with hemoglobin below 100 g/l
boolean
C0002871 (UMLS CUI [1])
C0518015 (UMLS CUI [2])
Renal Insufficiency | Estimated Glomerular Filtration Rate
Item
6. renal insufficiency with egf below 0.7 ml/s
boolean
C1565489 (UMLS CUI [1])
C3811844 (UMLS CUI [2])
Atrial Fibrillation
Item
7. atrial fibrillation - present during screening test
boolean
C0004238 (UMLS CUI [1])
Other medical condition Interferes with Research data | Physical Examination | Laboratory Procedures | Electrocardiography | Lung disease | Nervous system disorder | Inflammatory disorder
Item
8. the presence of other medical condition, which occurs during physical examination, laboratory tests, ecg, including pulmonary, neurological or inflammatory disease, which would be considered by the examiner to distort the consistency of data
boolean
C3843040 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0681873 (UMLS CUI [1,3])
C0031809 (UMLS CUI [2])
C0022885 (UMLS CUI [3])
C1623258 (UMLS CUI [4])
C0024115 (UMLS CUI [5])
C0027765 (UMLS CUI [6])
C1290884 (UMLS CUI [7])