B-cell Indolent Non-Hodgkin Lymphoma Relapsed | B-cell Indolent Non-Hodgkin Lymphoma refractory | Status post Rituximab therapy
Item
the patient has biopsy-confirmed diagnosis of indolent b-cell nhl documented as relapsed or refractory inhl (following rituximab-based therapy).
boolean
C1334170 (UMLS CUI [1,1])
C0004561 (UMLS CUI [1,2])
C0205336 (UMLS CUI [1,3])
C1334170 (UMLS CUI [2,1])
C0004561 (UMLS CUI [2,2])
C0205269 (UMLS CUI [2,3])
C0231290 (UMLS CUI [3,1])
C4047978 (UMLS CUI [3,2])
B-Cell Lymphoma indolent | Type Quantity
Item
the patient has one of the following types of indolent b-cell lymphoma:
boolean
C0079731 (UMLS CUI [1,1])
C0234227 (UMLS CUI [1,2])
C0332307 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
Follicular Lymphoma Grade
Item
follicular lymphoma grade 1, 2, or 3a
boolean
C0024301 (UMLS CUI [1,1])
C0441800 (UMLS CUI [1,2])
Marginal zone lymphoma
Item
marginal zone lymphoma
boolean
C0242647 (UMLS CUI [1])
Waldenstrom Macroglobulinemia
Item
lymphoplasmacytic lymphoma
boolean
C0024419 (UMLS CUI [1])
Small Lymphocytic Lymphoma
Item
small lymphocytic lymphoma
boolean
C0855095 (UMLS CUI [1])
Hematologic function | Exception Bone Marrow Involvement Lymphoma | Exception Hypersplenism caused by Lymphoma
Item
the patient has adequate haematologic function (unless abnormalities are related to lymphoma involvement of the bone marrow or hypersplenism caused by lymphoma).
boolean
C0221130 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C1517677 (UMLS CUI [2,2])
C0024299 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0020532 (UMLS CUI [3,2])
C0015127 (UMLS CUI [3,3])
C0024299 (UMLS CUI [3,4])
Inclusion criteria Chronic Lymphocytic Leukemia
Item
inclusion criteria for cll:
boolean
C1512693 (UMLS CUI [1,1])
C0023434 (UMLS CUI [1,2])
Chronic Lymphocytic Leukemia Symptomatic Untreated | Binet Staging System | Rai Staging System | Patient need for Therapy
Item
the patient has previously confirmed (according to who criteria) untreated symptomatic chronic b-cell lymphocytic leukemia binet stage b or binet stage c or rai stage ii to iv in need of medical treatment.
boolean
C0023434 (UMLS CUI [1,1])
C0231220 (UMLS CUI [1,2])
C0332155 (UMLS CUI [1,3])
C1511118 (UMLS CUI [2])
C1514715 (UMLS CUI [3])
C0686904 (UMLS CUI [4,1])
C0087111 (UMLS CUI [4,2])
ECOG performance status
Item
the patient has an eastern cooperative oncology group (ecog) performance status of 0-2.
boolean
C1520224 (UMLS CUI [1])
Study Subject Participation Status | Clinical Trial
Item
the patient has participated in a clinical study <30 days prior to the screening visit.
boolean
C2348568 (UMLS CUI [1])
C0008976 (UMLS CUI [2])
Patient Condition Quantity
Item
the patient has one or more of the following conditions:
boolean
C0030705 (UMLS CUI [1,1])
C0348080 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
Lymphoma transformation
Item
active transformed lymphoma
boolean
C0024299 (UMLS CUI [1,1])
C0040682 (UMLS CUI [1,2])
Central nervous system lymphoma | Meningeal Lymphoma
Item
any history of central nervous system or leptomeningeal lymphoma
boolean
C0280803 (UMLS CUI [1])
C2213017 (UMLS CUI [2])
Cancer Other
Item
an active malignancy other than the target cancer within the past 5 years
boolean
C1707251 (UMLS CUI [1])
HIV
Item
human immunodeficiency virus
boolean
C0019682 (UMLS CUI [1])
Protocol Compliance Unlikely | Study Subject Participation Status Inappropriate
Item
the patient is, in the investigator's opinion, unlikely to comply with the protocol or is unsuitable for any reason.
boolean
C0525058 (UMLS CUI [1,1])
C0750558 (UMLS CUI [1,2])
C2348568 (UMLS CUI [2,1])
C1548788 (UMLS CUI [2,2])
Eligibility Criteria Additional
Item
other inclusion and exclusion criteria may apply.
boolean
C1516637 (UMLS CUI [1,1])
C1524062 (UMLS CUI [1,2])