Hypertension, mild | Hypertension, moderate | Systolic Pressure | Diastolic blood pressure
Item
mild or moderate hypertension (systolic blood pressure 130 - 160 mmhg and diastolic blood pressure ≤ 100 mmhg)
boolean
C3276943 (UMLS CUI [1])
C1969581 (UMLS CUI [2])
C0871470 (UMLS CUI [3])
C0428883 (UMLS CUI [4])
Age
Item
age 30 - 75 years
boolean
C0001779 (UMLS CUI [1])
Body Weight
Item
body weight ≥ 60 kg
boolean
C0005910 (UMLS CUI [1])
Stable body weight
Item
stable body weight
boolean
C0517386 (UMLS CUI [1])
Childbearing Potential Contraceptive methods
Item
use of effective contraception in women of childbearing potential
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Body mass index
Item
body mass index ≥ 35
boolean
C1305855 (UMLS CUI [1])
Antihypertensive therapy | NSAID High dose Regular | Cyclosporine | Tacrolimus
Item
antihypertensive drug treatment, regular high dose nsaid treatment and the use of cyclosporine or tacrolimus
boolean
C0585941 (UMLS CUI [1])
C0003211 (UMLS CUI [2,1])
C0444956 (UMLS CUI [2,2])
C0205272 (UMLS CUI [2,3])
C0010592 (UMLS CUI [3])
C0085149 (UMLS CUI [4])
Diabetes Mellitus, Insulin-Dependent | Diabetes Mellitus, Non-Insulin-Dependent
Item
diabetes (type 1 and 2)
boolean
C0011854 (UMLS CUI [1])
C0011860 (UMLS CUI [2])
Anemia | Electrolytes abnormal | Proteinuria | Liver Dysfunction | Abnormal renal function | Thyroid function tests abnormal | Biochemical finding Clinical Significance | Hematology Clinical Significance
Item
anemia, abnormal electrolytes, proteinuria, abnormal liver, kidney and thyroid function, clinically significant biochemistry, any other clinically significant hematology and/or biochemistry at the investigator's discretion
boolean
C0002871 (UMLS CUI [1])
C0151613 (UMLS CUI [2])
C0033687 (UMLS CUI [3])
C0086565 (UMLS CUI [4])
C0151746 (UMLS CUI [5])
C0476414 (UMLS CUI [6])
C0428132 (UMLS CUI [7,1])
C2826293 (UMLS CUI [7,2])
C0200627 (UMLS CUI [8,1])
C2826293 (UMLS CUI [8,2])
Cardiovascular Disease | Myocardial Infarction | Angina, Unstable | Coronary Artery Bypass Surgery | Percutaneous Transluminal Coronary Angioplasty | Transient Ischemic Attack | Cerebrovascular accident | Congestive heart failure
Item
cardiovascular disease (myocardial infarction, unstable angina pectoris, coronary artery bypass graft, percutaneous transluminal coronary angioplasty, temporal ischemic attack within six months prior to screening) including stroke and congestive heart failure
boolean
C0007222 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
C0002965 (UMLS CUI [3])
C0010055 (UMLS CUI [4])
C2936173 (UMLS CUI [5])
C0007787 (UMLS CUI [6])
C0038454 (UMLS CUI [7])
C0018802 (UMLS CUI [8])
Secondary hypertension | History of cancer | Malignant disease
Item
secondary hypertension history of cancer or malignant disease within the past five years
boolean
C0155616 (UMLS CUI [1])
C0455471 (UMLS CUI [2])
C0442867 (UMLS CUI [3])
Metabolic Disease | Gastrointestinal Disease | Disease Interferes with Research results | Disease Interferes with Patient safety
Item
any metabolic disease, gastrointestinal disorder or other clinically significant disease/disorder which in the investigator's opinion could interfere with the results of the study or the safety of the subjects
boolean
C0025517 (UMLS CUI [1])
C0017178 (UMLS CUI [2])
C0012634 (UMLS CUI [3,1])
C0521102 (UMLS CUI [3,2])
C0683954 (UMLS CUI [3,3])
C0012634 (UMLS CUI [4,1])
C0521102 (UMLS CUI [4,2])
C1113679 (UMLS CUI [4,3])
Allergy to fish | Allergy to seafood | Allergy to citrus fruit | FOOD ALLERGY TO MULTIPLE FOOD
Item
fish and other seafood allergies, citrus allergy, multiple food allergies
boolean
C0856904 (UMLS CUI [1])
C0685900 (UMLS CUI [2])
C1690012 (UMLS CUI [3])
C0744084 (UMLS CUI [4])
Alcohol abuse
Item
alcohol abuse
boolean
C0085762 (UMLS CUI [1])
Tobacco use | Snuff use | Nicotine user
Item
smokers and tobacco/snuff/nicotine users
boolean
C0543414 (UMLS CUI [1])
C0454000 (UMLS CUI [2])
C4302494 (UMLS CUI [3])
Dietary Supplements Targeted Lowering Blood Pressure
Item
consumption of food supplements targeted to blood pressure lowering within 30 days before randomization
boolean
C0242295 (UMLS CUI [1,1])
C1521840 (UMLS CUI [1,2])
C2003888 (UMLS CUI [1,3])
C0005823 (UMLS CUI [1,4])
Pregnancy | Breast Feeding | Pregnancy, Planned
Item
pregnant and lactating mothers, women, planning for pregnancy during the study
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032992 (UMLS CUI [3])
Study Subject Participation Status | Clinical Trials | Intervention Clinical
Item
participation in clinical trials 30 days prior to this study and participation in other clinical intervention
boolean
C2348568 (UMLS CUI [1])
C0008976 (UMLS CUI [2])
C0184661 (UMLS CUI [3,1])
C0205210 (UMLS CUI [3,2])