Essential Hypertension
Item
participant has a diagnosis of essential hypertension.
boolean
C0085580 (UMLS CUI [1])
Antihypertensive therapy | Treatment Dual Hypertensive disease | Ability Discontinue Antihypertensive Agents
Item
participant is being treated with single or dual treatment for hypertension and will be able to discontinue the prior antihypertensive medication.
boolean
C0585941 (UMLS CUI [1])
C0087111 (UMLS CUI [2,1])
C0205173 (UMLS CUI [2,2])
C0020538 (UMLS CUI [2,3])
C0085732 (UMLS CUI [3,1])
C1444662 (UMLS CUI [3,2])
C0003364 (UMLS CUI [3,3])
Sitting diastolic blood pressure mean
Item
participant has a mean trough sidbp of ≥ 90 mmhg and < 110 mmhg.
boolean
C1319894 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
Sitting systolic blood pressure mean
Item
participant has a mean trough sisbp of ≥ 140 mmhg and < 200 mmhg.
boolean
C1319893 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
Abnormality Clinical Significance Absent
Item
participant has no clinically significant abnormality at screening visit.
boolean
C1704258 (UMLS CUI [1,1])
C2826293 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Antihypertensive Agents Quantity
Item
participant is currently taking > 2 antihypertensive medications.
boolean
C0003364 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
Multiple allergies Ingredient Losartan Potassium | Severe allergy Ingredient Losartan Potassium | Multiple allergies Ingredient Preminent | Severe allergy Ingredient Preminent | Multiple allergies Ingredient Amlodipine | Severe allergy Ingredient Amlodipine | Multiple allergies Ingredient Dihydropyridine | Severe allergy Ingredient Dihydropyridine | Multiple allergies Ingredient Thiazide | Severe allergy Ingredient Thiazide | Multiple allergies Ingredient Chlorthalidone | Severe allergy Ingredient Chlorthalidone
Item
participant has a history of significant multiple and/or severe allergies to ingredients of nu-lotan or preminent, amlodipine or dihydropyridine drug, and thiazide drug or related drug (i.e., sulfonamide-containing "chlortalidone" medicines).
boolean
C0740281 (UMLS CUI [1,1])
C1550600 (UMLS CUI [1,2])
C0700492 (UMLS CUI [1,3])
C2945656 (UMLS CUI [2,1])
C1550600 (UMLS CUI [2,2])
C0700492 (UMLS CUI [2,3])
C0740281 (UMLS CUI [3,1])
C1550600 (UMLS CUI [3,2])
C0138304 (UMLS CUI [3,3])
C2945656 (UMLS CUI [4,1])
C1550600 (UMLS CUI [4,2])
C0138304 (UMLS CUI [4,3])
C0740281 (UMLS CUI [5,1])
C1550600 (UMLS CUI [5,2])
C0051696 (UMLS CUI [5,3])
C2945656 (UMLS CUI [6,1])
C1550600 (UMLS CUI [6,2])
C0051696 (UMLS CUI [6,3])
C0740281 (UMLS CUI [7,1])
C1550600 (UMLS CUI [7,2])
C0220821 (UMLS CUI [7,3])
C2945656 (UMLS CUI [8,1])
C1550600 (UMLS CUI [8,2])
C0220821 (UMLS CUI [8,3])
C0740281 (UMLS CUI [9,1])
C1550600 (UMLS CUI [9,2])
C0541746 (UMLS CUI [9,3])
C2945656 (UMLS CUI [10,1])
C1550600 (UMLS CUI [10,2])
C0541746 (UMLS CUI [10,3])
C0740281 (UMLS CUI [11,1])
C1550600 (UMLS CUI [11,2])
C0008294 (UMLS CUI [11,3])
C2945656 (UMLS CUI [12,1])
C1550600 (UMLS CUI [12,2])
C0008294 (UMLS CUI [12,3])
Recreational drug use | Illicit medication use | Substance Use Disorders
Item
participant is, at the time of signing informed consent, a user of recreational or illicit drugs or has had a recent history within the last year of drug or alcohol abuse or dependence.
boolean
C0013146 (UMLS CUI [1])
C0281875 (UMLS CUI [2])
C0038586 (UMLS CUI [3])
Pregnancy | Breast Feeding | Pregnancy, Planned | Pregnancy test positive
Item
participant is pregnant or breastfeeding, or expecting to conceive or the pregnancy test is positive at screening visit (visit 1).
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032992 (UMLS CUI [3])
C0240802 (UMLS CUI [4])
Study Subject Participation Status | Investigational New Drugs | Investigational Medical Device
Item
participant is currently participating or has participated in a study with an investigational compound or device within 30 days of signing informed consent.
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
C2346570 (UMLS CUI [3])