Essential Hypertension
Item
essential hypertensive patients
boolean
C0085580 (UMLS CUI [1])
Antihypertensive Agents | Sitting diastolic blood pressure mean
Item
if already taking antihypertensive drugs, mean seated diastolic blood pressure (dbp) must be >=90 and >=114 mmhg
boolean
C0003364 (UMLS CUI [1])
C1319894 (UMLS CUI [2,1])
C0444504 (UMLS CUI [2,2])
Antihypertensive Agents Absent | Sitting diastolic blood pressure mean
Item
if not taking any antihypertensive drugs, mean seated dbp must be >=95 and >=114 mmhg
boolean
C0003364 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1319894 (UMLS CUI [2,1])
C0444504 (UMLS CUI [2,2])
Ability Discontinue Antihypertensive Agents | Risk Absent Patient
Item
able to stop all current antihypertensive drugs without risk to the patient based on the investigators opinion.
boolean
C0085732 (UMLS CUI [1,1])
C1444662 (UMLS CUI [1,2])
C0003364 (UMLS CUI [1,3])
C0035647 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0030705 (UMLS CUI [2,3])
Antihypertensive Agents Quantity
Item
patients taking 3 or more antihypertensive drugs at signing the informed consent form
boolean
C0003364 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
Secondary hypertension | Secondary hypertension Suspected
Item
patients with known or suspected secondary hypertension
boolean
C0155616 (UMLS CUI [1])
C0155616 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
Cardiac Arrhythmia
Item
patients with clinically relevant cardiac arrhythmia
boolean
C0003811 (UMLS CUI [1])
Congestive heart failure New York Heart Association Classification
Item
congestive heart failure with new york heart association (nyha) functional class iii-iv
boolean
C0018802 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Cardiovascular event Recent
Item
patients with recent cardiovascular events
boolean
C1320716 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Cerebrovascular accident | Transient Ischemic Attack
Item
patients with a history of stroke or transient ischaemic attack within last 6 months before signing the informed consent form
boolean
C0038454 (UMLS CUI [1])
C0007787 (UMLS CUI [2])
Deterioration Sudden Renal function | Angiotensin II receptor antagonist | Angiotensin-Converting Enzyme Inhibitors | Status post Kidney Transplantation | Status post Nephrectomy
Item
patients with a history of sudden deterioration of renal function with angiotensin ii receptor blockers (arbs) or angiotensin converting enzyme (ace) inhibitors; or patients with post-renal transplant or post-nephrectomy
boolean
C0868945 (UMLS CUI [1,1])
C1276802 (UMLS CUI [1,2])
C0232804 (UMLS CUI [1,3])
C0521942 (UMLS CUI [2])
C0003015 (UMLS CUI [3])
C0231290 (UMLS CUI [4,1])
C0022671 (UMLS CUI [4,2])
C0231290 (UMLS CUI [5,1])
C0027695 (UMLS CUI [5,2])
Symptoms Angioedema | Facial swelling with Dyspnea | Tongue swelling with Dyspnea | Pharyngeal swelling with Dyspnea | Laryngeal Edema with Dyspnea
Item
patients who have previously experienced characteristic symptoms of angioedema (such as facial, tongue, pharyngeal, or laryngeal swelling with dyspnea) during treatment with arbs or ace inhibitors
boolean
C1457887 (UMLS CUI [1,1])
C0002994 (UMLS CUI [1,2])
C0151602 (UMLS CUI [2,1])
C0332287 (UMLS CUI [2,2])
C0013404 (UMLS CUI [2,3])
C0236068 (UMLS CUI [3,1])
C0332287 (UMLS CUI [3,2])
C0013404 (UMLS CUI [3,3])
C1704205 (UMLS CUI [4,1])
C0332287 (UMLS CUI [4,2])
C0013404 (UMLS CUI [4,3])
C0023052 (UMLS CUI [5,1])
C0332287 (UMLS CUI [5,2])
C0013404 (UMLS CUI [5,3])
Hypersensitivity Investigational New Drug Component | Hypersensitivity Dihydropyridine derivatives
Item
patients with known hypersensitivity to any component of the investigational product, or a known hypersensitivity to dihydropyridine-derived drugs
boolean
C0020517 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
C1705248 (UMLS CUI [1,3])
C0020517 (UMLS CUI [2,1])
C3653438 (UMLS CUI [2,2])
Liver Dysfunction | Renal dysfunction
Item
patients with hepatic and/or renal dysfunction
boolean
C0086565 (UMLS CUI [1])
C3279454 (UMLS CUI [2])
Premenopausal state | Breast Feeding | Pregnancy
Item
pre-menopausal women who are nursing or pregnant
boolean
C0232969 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032961 (UMLS CUI [3])