Age
Item
male or female and aged 18 years or over.
boolean
C0001779 (UMLS CUI [1])
Hypotension, Orthostatic | Autonomic Failure Primary | Parkinson Disease | Multiple System Atrophy | Pure Autonomic Failure
Item
clinical diagnosis of orthostatic hypotension associated with primary autonomic failure (parkinson disease, multiple system atrophy and pure autonomic failure).
boolean
C0020651 (UMLS CUI [1])
C0393911 (UMLS CUI [2,1])
C0205225 (UMLS CUI [2,2])
C0030567 (UMLS CUI [3])
C0393571 (UMLS CUI [4])
C0393911 (UMLS CUI [5])
Systolic Pressure Decrease Amount | Diastolic blood pressure Decrease Amount | Status post Standing
Item
a documented fall in systolic blood pressure of at least 20 mmhg, or in diastolic blood pressure of at least 10 mmhg, within 3 minutes after standing.
boolean
C0871470 (UMLS CUI [1,1])
C0547047 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0428883 (UMLS CUI [2,1])
C0547047 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0231290 (UMLS CUI [3,1])
C0231472 (UMLS CUI [3,2])
Supine hypertension | Systolic Pressure | Diastolic blood pressure
Item
supine hypertension, defined as a systolic blood pressure >150 mm hg or diastolic blood pressure > 90 mm hg.
boolean
C4076686 (UMLS CUI [1])
C0871470 (UMLS CUI [2])
C0428883 (UMLS CUI [3])
Informed Consent
Item
provide written informed consent to participate in the study and understand that they may withdraw their consent at any time without prejudice to their future medical care.
boolean
C0021430 (UMLS CUI [1])
Prescribed medication Dose Changed | Prescribed medication Frequency Changed | Prescribed medication Type Changed
Item
have changed dose, frequency and or type of prescribed medication, within two weeks of study start.
boolean
C2239117 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
C2239117 (UMLS CUI [2,1])
C0439603 (UMLS CUI [2,2])
C0392747 (UMLS CUI [2,3])
C2239117 (UMLS CUI [3,1])
C0332307 (UMLS CUI [3,2])
C0392747 (UMLS CUI [3,3])
Childbearing Potential Contraceptive methods Absent
Item
women of childbearing potential who are not using a medically accepted contraception.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Heart Disease | Systemic disease | Liver disease | Kidney Disease
Item
have, in the investigator's opinion, any significant cardiac, systemic, hepatic, or renal illness.
boolean
C0018799 (UMLS CUI [1])
C0442893 (UMLS CUI [2])
C0023895 (UMLS CUI [3])
C0022658 (UMLS CUI [4])
Diabetes Mellitus | Diabetes Insipidus
Item
diabetes mellitus or insipidus.
boolean
C0011849 (UMLS CUI [1])
C0011848 (UMLS CUI [2])
Abnormality Clinical examination | Laboratory test result abnormal
Item
in the investigator's opinion, have clinically significant abnormalities on clinical examination or laboratory testing.
boolean
C1704258 (UMLS CUI [1,1])
C1456356 (UMLS CUI [1,2])
C0438215 (UMLS CUI [2])
Poor compliance Due to Social situation | Poor compliance Due to Family problem
Item
in the investigator's opinion, are unable to adequately co-operate because of individual or family situation.
boolean
C0032646 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0748872 (UMLS CUI [1,3])
C0032646 (UMLS CUI [2,1])
C0678226 (UMLS CUI [2,2])
C0424960 (UMLS CUI [2,3])
Mental disorder Interferes with Diagnosis | Mental disorder Interferes with Completion of clinical trial | Schizophrenia | Major Depressive Disorder | Dementia
Item
in the investigator's opinion, are suffering from a mental disorder that interferes with the diagnosis and/or with the conduct of the study, e.g. schizophrenia, major depression, dementia.
boolean
C0004936 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0011900 (UMLS CUI [1,3])
C0004936 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C2732579 (UMLS CUI [2,3])
C0036341 (UMLS CUI [3])
C1269683 (UMLS CUI [4])
C0497327 (UMLS CUI [5])
Protocol Compliance Unable | Protocol Compliance Unwilling
Item
are not able or willing to comply with the study requirements for the duration of the study.
boolean
C0525058 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
C0525058 (UMLS CUI [2,1])
C0558080 (UMLS CUI [2,2])
Adrenergic beta-1 Receptor Antagonists | Amiodarone | Nitrates | Adrenergic alpha-Antagonists | tamsulosin
Item
persons on drugs with beta-blocking potential (e.g., amiodarone), persons taking scheduled or as needed nitrates and persons on drugs with alpha-blocking potential (e.g. tamsulosin).
boolean
C0304516 (UMLS CUI [1])
C0002598 (UMLS CUI [2])
C0028125 (UMLS CUI [3])
C0001641 (UMLS CUI [4])
C0257343 (UMLS CUI [5])