Chronic Hepatitis C Genotype
Item
documented chronic hepatitis c infection, genotype 1 at screening
boolean
C0524910 (UMLS CUI [1,1])
C1533728 (UMLS CUI [1,2])
Therapy naive | Absence Exposure to PEGINTERFERON | Absence Exposure to Ribavirin | Absence Investigational Therapy Hepatitis C
Item
treatment-naïve; no prior exposure to pegylated interferon, ribavirin, or experimental hcv therapy
boolean
C0919936 (UMLS CUI [1])
C0332197 (UMLS CUI [2,1])
C0332157 (UMLS CUI [2,2])
C0982327 (UMLS CUI [2,3])
C0332197 (UMLS CUI [3,1])
C0332157 (UMLS CUI [3,2])
C0035525 (UMLS CUI [3,3])
C0332197 (UMLS CUI [4,1])
C0949266 (UMLS CUI [4,2])
C0019196 (UMLS CUI [4,3])
Therapeutic procedure Experience | Therapy partial responder | Recurrent disease | Viral Breakthrough | Null responder | Standard of Care Previous | pegylated interferon alfa | Ribavirin
Item
treatment-experienced patients including partial responders, prior relapse, prior viral breakthrough, and null responders; prior treatment with current standard of care (pegylated interferon alfa and ribavirin)
boolean
C0087111 (UMLS CUI [1,1])
C0596545 (UMLS CUI [1,2])
C4285679 (UMLS CUI [2])
C0277556 (UMLS CUI [3])
C4053869 (UMLS CUI [4])
C0456148 (UMLS CUI [5,1])
C0919876 (UMLS CUI [5,2])
C2936643 (UMLS CUI [6,1])
C0205156 (UMLS CUI [6,2])
C0907160 (UMLS CUI [7])
C0035525 (UMLS CUI [8])
Pregnancy | Breast Feeding
Item
female patients who are pregnant or breast feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Hepatitis C | Exception Hepatitis C virus genotype determination
Item
infection with non-genotype 1 hcv
boolean
C0019196 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C1533728 (UMLS CUI [2,2])
Patients Therapy naive | Prior Therapy Hepatitis C
Item
for treatment-naïve patients: any previous treatment for hcv infection
boolean
C0030705 (UMLS CUI [1,1])
C0919936 (UMLS CUI [1,2])
C1514463 (UMLS CUI [2,1])
C0019196 (UMLS CUI [2,2])
Patients Therapeutic procedure Experience | Prior Therapy DIRECT ACTING ANTIVIRALS Hepatitis C
Item
for treatment-experienced patients: previous treatment with any direct-acting antivirals for hcv infection
boolean
C0030705 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
C0596545 (UMLS CUI [1,3])
C1514463 (UMLS CUI [2,1])
C3653501 (UMLS CUI [2,2])
C0019196 (UMLS CUI [2,3])
HIV coinfection | HBV coinfection
Item
known hiv or hbv co-infection
boolean
C4062778 (UMLS CUI [1])
C2242656 (UMLS CUI [2])
Medical contraindication PEGINTERFERON | Medical contraindication Ribavirin
Item
any medical contraindications to peg-inf or rbv therapy
boolean
C1301624 (UMLS CUI [1,1])
C0982327 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0035525 (UMLS CUI [2,2])
Liver disease Cause Other
Item
history of any other known cause of liver disease
boolean
C0023895 (UMLS CUI [1,1])
C0015127 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])