Heart failure Advanced
Item
patients with advanced heart failure
boolean
C0018801 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
Age
Item
1. age 18-80 years
boolean
C0001779 (UMLS CUI [1])
Heart failure New York Heart Association Classification Duration
Item
2. new york heart association class iii-iv heart failure for 45 of the last 60 days
boolean
C0018801 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
Left ventricular ejection fraction
Item
3. left ventricular ejection fraction ≤ 35%
boolean
C0428772 (UMLS CUI [1])
Heart failure | Symptoms Typical Duration
Item
4. heart failure diagnosis or typical symptoms for 12 months
boolean
C0018801 (UMLS CUI [1])
C1457887 (UMLS CUI [2,1])
C3538928 (UMLS CUI [2,2])
C0449238 (UMLS CUI [2,3])
Adrenergic beta-1 Receptor Antagonists Oral | Angiotensin-Converting Enzyme Inhibitors Oral | Angiotensin II receptor antagonist Oral | Aldosterone Antagonists Oral | Medical contraindication Pharmaceutical Preparations | Intolerance to Pharmaceutical Preparations
Item
5. use of evidence based oral medications (beta-blockers, ace-inhibitors/arbs, aldosterone antagonist) for at least 3 months prior to enrollment or documented medication contraindication or intolerance.
boolean
C0304516 (UMLS CUI [1,1])
C1527415 (UMLS CUI [1,2])
C0003015 (UMLS CUI [2,1])
C1527415 (UMLS CUI [2,2])
C0521942 (UMLS CUI [3,1])
C1527415 (UMLS CUI [3,2])
C0002007 (UMLS CUI [4,1])
C1527415 (UMLS CUI [4,2])
C1301624 (UMLS CUI [5,1])
C0013227 (UMLS CUI [5,2])
C1744706 (UMLS CUI [6,1])
C0013227 (UMLS CUI [6,2])
Hospitalization Due to Heart Failure
Item
6. hospitalization for heart failure within the previous 12 months (other than for elective procedure)
boolean
C3898876 (UMLS CUI [1])
Informed Consent
Item
7. informed consent given
boolean
C0021430 (UMLS CUI [1])
Criteria Additional Quantity
Item
in addition, they must have at least one of the following:
boolean
C0243161 (UMLS CUI [1,1])
C1524062 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
Hospitalization Due to Heart Failure Additional | Hospitalization Quantity Inpatient stay | Heart failure Principal diagnosis | Heart failure Secondary diagnosis
Item
an additional unplanned hospitalization during the previous 12 months for a total of at least 2 inpatient hospitalizations lasting >24 hours with heart failure as the primary or secondary diagnosis within the previous 12 months
boolean
C3898876 (UMLS CUI [1,1])
C1524062 (UMLS CUI [1,2])
C0019993 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0420512 (UMLS CUI [2,3])
C0018801 (UMLS CUI [3,1])
C0332137 (UMLS CUI [3,2])
C0018801 (UMLS CUI [4,1])
C0332138 (UMLS CUI [4,2])
Oxygen uptake Peak level | Age | Gender | Other Coding | Respiratory Exchange Ratio Cardiopulmonary Exercise Test
Item
1. peak oxygen uptake (vo2) <55% of age- and sex-predicted (using wasserman equation) or a peak vo2 ≤16 ml/kg/min for men and ≤14 ml/kg/min for women in a test with an rer >1.08 on cardiopulmonary exercise testing.
boolean
C0429627 (UMLS CUI [1,1])
C0444505 (UMLS CUI [1,2])
C0001779 (UMLS CUI [2])
C0079399 (UMLS CUI [3])
C3846158 (UMLS CUI [4])
C4049826 (UMLS CUI [5,1])
C2959886 (UMLS CUI [5,2])
6-Minute Walk Test Distance | Limitation Absent | Exception Limitation cardiac
Item
2. 6-minute walk distance <300 meters without non-cardiac limitation.
boolean
C0430515 (UMLS CUI [1,1])
C0012751 (UMLS CUI [1,2])
C0449295 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0449295 (UMLS CUI [3,2])
C0018787 (UMLS CUI [3,3])
Brain natriuretic peptide measurement | N-Terminal ProB-type Natriuretic Peptide Measurement | Outpatient | Discharge from hospital
Item
3. serum bnp > 1000 (nt-probnp > 4000 pg/ml) as outpatient or at hospital discharge.
boolean
C1095989 (UMLS CUI [1])
C3272900 (UMLS CUI [2])
C0029921 (UMLS CUI [3])
C0586003 (UMLS CUI [4])
Heart failure Score
Item
seattle heart failure model score > 1.5.
boolean
C0018801 (UMLS CUI [1,1])
C0449820 (UMLS CUI [1,2])
Age
Item
1. age >80 years or <18 years
boolean
C0001779 (UMLS CUI [1])
Diagnosis Survival Limited | Exception Heart Diseases
Item
2. non-cardiac diagnosis anticipated to limit 2-year survival (≥30-50% mortality within 2 years from non-cardiac diagnosis)
boolean
C0011900 (UMLS CUI [1,1])
C0038952 (UMLS CUI [1,2])
C0439801 (UMLS CUI [1,3])
C1705847 (UMLS CUI [2,1])
C0018799 (UMLS CUI [2,2])
Primary functional limitation | Diagnosis Except Heart Disease
Item
3. primary functional limitation from non-cardiac diagnosis even if not likely to limit survival
boolean
C4018823 (UMLS CUI [1])
C0011900 (UMLS CUI [2,1])
C0332300 (UMLS CUI [2,2])
C0018799 (UMLS CUI [2,3])
QRS duration | Biventricular pacemaker insertion
Item
4. qrs > 120msec and planned biventricular pacemaker implant or biventricular pacemaker implantation within past 90 days
boolean
C0429025 (UMLS CUI [1])
C3805138 (UMLS CUI [2])
Inotropic agent Intravenous
Item
5. current home intravenous inotrope therapy
boolean
C0304509 (UMLS CUI [1,1])
C1522726 (UMLS CUI [1,2])
Chronic haemodialysis | Chronic peritoneal dialysis
Item
6. chronic hemodialysis or peritoneal dialysis
boolean
C1740835 (UMLS CUI [1])
C0455150 (UMLS CUI [2])
Heart-Assist Device Surgery Scheduled | Involvement with Ventricle Absent
Item
7. scheduled for non-ventricular assist device cardiac surgery on current hospital admission
boolean
C0018831 (UMLS CUI [1,1])
C0543467 (UMLS CUI [1,2])
C0205539 (UMLS CUI [1,3])
C1314939 (UMLS CUI [2,1])
C0018827 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
Medical contraindication anatomical Cardiac Surgery | Medical contraindication Major Cardiac Surgery | Pneumonectomy | Connective Tissue Disease Advanced
Item
8. obvious anatomical or other major contra-indication to any cardiac surgery in the future (e.g. previous pneumonectomy, advanced connective tissue disease)
boolean
C1301624 (UMLS CUI [1,1])
C0220784 (UMLS CUI [1,2])
C0018821 (UMLS CUI [1,3])
C1301624 (UMLS CUI [2,1])
C0205164 (UMLS CUI [2,2])
C0018821 (UMLS CUI [2,3])
C0032284 (UMLS CUI [3])
C0009782 (UMLS CUI [4,1])
C0205179 (UMLS CUI [4,2])
Patient on waiting list Heart Transplantation | UNOS Status
Item
9. actively listed for heart transplant as unos status 1 or 2
boolean
C0422768 (UMLS CUI [1,1])
C0018823 (UMLS CUI [1,2])
C3826868 (UMLS CUI [2,1])
C0449438 (UMLS CUI [2,2])
Amyloidosis Cardiac
Item
10. history of cardiac amyloidosis
boolean
C0002726 (UMLS CUI [1,1])
C1522601 (UMLS CUI [1,2])
Aortic Valve Stenosis Moderate | Aortic stenosis severe | MITRAL STENOSIS MODERATE | Mitral Valve Stenosis Severe | Congenital Heart Defect structural
Item
11. dominant lesion of at least moderate aortic or mitral stenosis or congenital structural heart defect.
boolean
C0003507 (UMLS CUI [1,1])
C0205081 (UMLS CUI [1,2])
C3806272 (UMLS CUI [2])
C0746601 (UMLS CUI [3])
C0026269 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
C0018798 (UMLS CUI [5,1])
C0678594 (UMLS CUI [5,2])