Hepatitis B, Chronic | Hepatitis B surface antigen positive
Item
documented chb infection with hbsag positive > 6 months
boolean
C0524909 (UMLS CUI [1])
C0149709 (UMLS CUI [2])
Hepatitis B e antigen positive | Hepatitis B, Chronic | Pregnancy
Item
hbeag+ chb pregnant women
boolean
C0392390 (UMLS CUI [1])
C0524909 (UMLS CUI [2])
C0032961 (UMLS CUI [3])
Gestational Age
Item
gestational age between 30-32 weeks
boolean
C0017504 (UMLS CUI [1])
Hepatitis B DNA Measurement
Item
hbv dna > 6 log10 copies/ml (or >200,000 iu/ml)
boolean
C3641250 (UMLS CUI [1])
Informed Consent Parent
Item
both mother and father of the child are willing to consent for the study
boolean
C0021430 (UMLS CUI [1,1])
C0030551 (UMLS CUI [1,2])
Exclusion Criteria Major
Item
major exclusion criteria:
boolean
C0680251 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
Coinfection Hepatitis A | HCV coinfection | Coinfection Hepatitis D | Coinfection Hepatitis E | Coinfection HIV-1 | Sexually Transmitted Diseases
Item
co-infection with hepatitis a, c, d, e, hiv-1 or sexually transmitted disease (std)
boolean
C0275524 (UMLS CUI [1,1])
C0019159 (UMLS CUI [1,2])
C1698259 (UMLS CUI [2])
C0275524 (UMLS CUI [3,1])
C0011226 (UMLS CUI [3,2])
C0275524 (UMLS CUI [4,1])
C0085293 (UMLS CUI [4,2])
C0275524 (UMLS CUI [5,1])
C0019704 (UMLS CUI [5,2])
C0036916 (UMLS CUI [6])
End Stage Liver Disease | Comorbidity Significant
Item
decompensated liver disease or significant co-morbidity
boolean
C0745744 (UMLS CUI [1])
C0009488 (UMLS CUI [2,1])
C0750502 (UMLS CUI [2,2])
Previous Abortion | Defect Fetal | Congenital malformation Pregnancy Previous
Item
history of abortion, or diagnosis of fetal defect, or congenital malformation in prior pregnancy
boolean
C0000790 (UMLS CUI [1])
C1457869 (UMLS CUI [2,1])
C0521457 (UMLS CUI [2,2])
C0000768 (UMLS CUI [3,1])
C0032961 (UMLS CUI [3,2])
C0205156 (UMLS CUI [3,3])
Antiviral Agents | Renal Insufficiency Due to Adefovir | Renal tubular disorder Due to Adefovir
Item
antiviral used within six months prior to this pregnancy, or history of renal or tubular function impairment due to adefovir.
boolean
C0003451 (UMLS CUI [1])
C1565489 (UMLS CUI [2,1])
C0678226 (UMLS CUI [2,2])
C0050175 (UMLS CUI [2,3])
C0151747 (UMLS CUI [3,1])
C0678226 (UMLS CUI [3,2])
C0050175 (UMLS CUI [3,3])
Management Chronic disease | Requirement Pharmaceutical Preparations Other | Biological Response Modifiers | Cytotoxic agent | Steroids
Item
requirement for other medication during pregnancy to manage other chronic disease(s) or concurrent treatment with immune-modulators, cytotoxic drugs, or steroids
boolean
C0376636 (UMLS CUI [1,1])
C0008679 (UMLS CUI [1,2])
C1514873 (UMLS CUI [2,1])
C0013227 (UMLS CUI [2,2])
C0205394 (UMLS CUI [2,3])
C0005525 (UMLS CUI [3])
C0304497 (UMLS CUI [4])
C0038317 (UMLS CUI [5])
Father Chronic Hepatitis B
Item
the biological father of the child had chb
boolean
C0015671 (UMLS CUI [1,1])
C0524909 (UMLS CUI [1,2])
Sign or Symptom Threatened miscarriage Early pregnancy
Item
clinical signs of threatened miscarriage in early pregnancy
boolean
C3540840 (UMLS CUI [1,1])
C0000821 (UMLS CUI [1,2])
C0747845 (UMLS CUI [1,3])
Liver carcinoma
Item
evidence of hepatocellular carcinoma
boolean
C2239176 (UMLS CUI [1])
Alanine aminotransferase increased maternal | Serum total bilirubin measurement maternal | Glomerular Filtration Rate maternal | Albumin measuremen maternal
Item
maternal alanine aminotransferase (alt) > or = 5 x upper limit of normal (u/ml), or total bilirubin > or = 2, or glomerular filtration rate (gfr) < 100, or albumin < 25 g/l
boolean
C0151905 (UMLS CUI [1,1])
C0026591 (UMLS CUI [1,2])
C1278039 (UMLS CUI [2,1])
C0026591 (UMLS CUI [2,2])
C0017654 (UMLS CUI [3,1])
C0026591 (UMLS CUI [3,2])
C0201838 (UMLS CUI [4,1])
C0026591 (UMLS CUI [4,2])
Deformity Fetal Ultrasonography
Item
evidence of fetal deformity by ultrasound examination
boolean
C0302142 (UMLS CUI [1,1])
C0521457 (UMLS CUI [1,2])
C0041618 (UMLS CUI [1,3])
Study Subject Participation Status | Clinical Trial
Item
patient is participating other clinical study
boolean
C2348568 (UMLS CUI [1])
C0008976 (UMLS CUI [2])