Heart failure
Item
clinical diagnosis of heart failure;
boolean
C0018801 (UMLS CUI [1])
Cardiac dysfunction
Item
objective evidence of cardiac dysfunctions as evidenced by at least one of the following:
boolean
C3277906 (UMLS CUI [1])
Left ventricular ejection fraction
Item
left ventricular ejection fraction ≤ 40%;
boolean
C0428772 (UMLS CUI [1])
Left atrium Dimension | Left atrium Dimension Height
Item
left atrial dimension >4.0 cm (or >2.5 cm/m in height)
boolean
C0225860 (UMLS CUI [1,1])
C0439534 (UMLS CUI [1,2])
C0225860 (UMLS CUI [2,1])
C0439534 (UMLS CUI [2,2])
C0489786 (UMLS CUI [2,3])
N-Terminal ProB-type Natriuretic Peptide Measurement | Brain natriuretic peptide measurement
Item
nt-probnp >400 pg/ml [>47.3 pmol/l] (or bnp >150 pg/ml)
boolean
C3272900 (UMLS CUI [1])
C1095989 (UMLS CUI [2])
Loop Diuretics
Item
current treatment with loop diuretics;
boolean
C0354100 (UMLS CUI [1])
Age
Item
age >18 years;
boolean
C0001779 (UMLS CUI [1])
Informed Consent
Item
willingness to provide informed consent
boolean
C0021430 (UMLS CUI [1])
Congenital heart disease
Item
congenital heart disease;
boolean
C0152021 (UMLS CUI [1])
Life threatening illness | Exception Heart failure
Item
any life-threatening disease other than heart failure;
boolean
C3846017 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0018801 (UMLS CUI [2,2])
Malignant Neoplasm Type Any | History of malignant neoplasm
Item
active malignancy of any type, or history of a malignancy within previous 5 years;
boolean
C0006826 (UMLS CUI [1,1])
C0332307 (UMLS CUI [1,2])
C1552551 (UMLS CUI [1,3])
C0455471 (UMLS CUI [2])
Heart Transplantation
Item
previous heart transplantation;
boolean
C0018823 (UMLS CUI [1])
Intravenous therapy Heart failure
Item
intra-venous therapy for heart failure given within the previous 72 hours;
boolean
C0455142 (UMLS CUI [1,1])
C0018801 (UMLS CUI [1,2])
Neuromuscular Disease Severe
Item
severe neuro-muscular disease;
boolean
C0027868 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
Angina, Unstable | Myocardial Infarction | Cerebrovascular accident
Item
history of unstable angina, myocardial infarction or stroke within 3 months prior to the study;
boolean
C0002965 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
C0038454 (UMLS CUI [3])
Pregnancy
Item
pregnancy;
boolean
C0032961 (UMLS CUI [1])
Therapeutic immunosuppression | Steroid therapy Rheumatoid Arthritis | Steroid therapy Obstructive Lung Disease
Item
treatment with immunosuppressive therapy, e.g. steroids for rheumatoid arthritis or obstructive lung disease;
boolean
C0021079 (UMLS CUI [1])
C0149783 (UMLS CUI [2,1])
C0003873 (UMLS CUI [2,2])
C0149783 (UMLS CUI [3,1])
C0600260 (UMLS CUI [3,2])
Renal dysfunction | Creatinine measurement, serum
Item
significant renal dysfunction, defined as serum creatinine >250 μmol/l [>2.8 mg/dl];
boolean
C3279454 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
Liver disease Severe | Increased liver function tests
Item
severe liver disease, defined as any liver function tests >3 times the upper limit of normal;
boolean
C0023895 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0877359 (UMLS CUI [2])
Study Protocol Comprehension Unable | Protocol Compliance Unable | Informed Consent Unable
Item
unable to understand and comply with protocol or to give informed consent.
boolean
C2348563 (UMLS CUI [1,1])
C0162340 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
C0525058 (UMLS CUI [2,1])
C1299582 (UMLS CUI [2,2])
C0021430 (UMLS CUI [3,1])
C1299582 (UMLS CUI [3,2])