Study Subject All
Item
for all participants:
boolean
C0681850 (UMLS CUI [1,1])
C0444868 (UMLS CUI [1,2])
Informed Consent
Item
1. before any study-specific procedures, the appropriate written informed consent must be obtained.
boolean
C0021430 (UMLS CUI [1])
Age
Item
2. male and female older than 18 years of age.
boolean
C0001779 (UMLS CUI [1])
Patients cardiac
Item
for the cardiac patients:
boolean
C0030705 (UMLS CUI [1,1])
C0018787 (UMLS CUI [1,2])
Patients Accepted Cardiothoracic surgery | Thoracic Surgical Procedures
Item
3. being accepted for cardiothoracic surgery with the use of open chest surgery
boolean
C0030705 (UMLS CUI [1,1])
C1272684 (UMLS CUI [1,2])
C2242990 (UMLS CUI [1,3])
C0524832 (UMLS CUI [2])
Left ventricular ejection fraction Echocardiography | Left ventricular ejection fraction MUGA scan | Left ventricular ejection fraction MRI
Item
4. a known left ventricular ejection fraction, either assessed by echocardiography, muga or mri. if lvef <40% a subject will be assigned to the chronic heart failure group, if lvef >40% a subject will be assigned to the control group.
boolean
C0428772 (UMLS CUI [1,1])
C0013516 (UMLS CUI [1,2])
C0428772 (UMLS CUI [2,1])
C0521317 (UMLS CUI [2,2])
C0428772 (UMLS CUI [3,1])
C0024485 (UMLS CUI [3,2])
Patients | Heart Disease Absent
Item
for the non-cardiac patients:
boolean
C0030705 (UMLS CUI [1])
C0018799 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Patients Accepted Orthopedic Surgical Procedures | Total Hip Replacement
Item
5. accepted for orthopedic surgery (e.g. total hip replacement) at the department of orthopedic surgery.
boolean
C0030705 (UMLS CUI [1,1])
C1272684 (UMLS CUI [1,2])
C1136201 (UMLS CUI [1,3])
C0040508 (UMLS CUI [2])
Medical condition Unstable | Hospitalization Except Heart Disease | At risk Complication | At risk Adverse event
Item
1. an unstable medical condition, defined as having been hospitalized for a non-cardiac condition within 4 weeks of screening, or otherwise unstable in the judgment of the investigator (e.g. at risk of complications or adverse events unrelated to study participation).
boolean
C3843040 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C0019993 (UMLS CUI [2,1])
C0332300 (UMLS CUI [2,2])
C0018799 (UMLS CUI [2,3])
C1444641 (UMLS CUI [3,1])
C0009566 (UMLS CUI [3,2])
C1444641 (UMLS CUI [4,1])
C0877248 (UMLS CUI [4,2])
Age
Item
2. younger than 18 years of age.
boolean
C0001779 (UMLS CUI [1])
Chronic Kidney Diseases
Item
3. clinical history of chronic kidney disease (at any point prior to registration).
boolean
C1561643 (UMLS CUI [1])
Liver disease
Item
4. any known hepatic disease.
boolean
C0023895 (UMLS CUI [1])
Alcohol abuse | DRUG ABUSE ILLICIT
Item
5. recent (within 3 months) history of alcohol or illicit drug abuse disorder, based on self-report.
boolean
C0085762 (UMLS CUI [1])
C0743253 (UMLS CUI [2])
Chemistry abnormal | Hematology finding abnormal | Urinalysis Parameters Abnormal
Item
6. clinically significant abnormality in chemistry, hematology, or urinalysis parameters performed within the screening period.
boolean
C0740327 (UMLS CUI [1])
C0475182 (UMLS CUI [2])
C0042014 (UMLS CUI [3,1])
C0449381 (UMLS CUI [3,2])
C0205161 (UMLS CUI [3,3])
Study Subject Participation Status | Investigational Medical Device | Investigational New Drugs
Item
7. participation in any investigational device or drug trial(s) or receiving investigational agent(s) within 30 days.
boolean
C2348568 (UMLS CUI [1])
C2346570 (UMLS CUI [2])
C0013230 (UMLS CUI [3])
Condition Study Subject Participation Status At risk | Condition Interferes with Research results | Condition Interferes with Study Subject Participation Status | Mental disorder Study Subject Participation Status At risk | Mental disorder Interferes with Research results | Mental disorder Interferes with Study Subject Participation Status | Social situation Study Subject Participation Status At risk | Social situation Interferes with Research results | Social situation Interferes with Study Subject Participation Status
Item
8. any condition (e.g. psychiatric illness, etc.) or situation that, in the investigator's opinion, could put the subject at significant risk, confound the study results, or interfere significantly with the subject's participation in the study.
boolean
C0348080 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C1444641 (UMLS CUI [1,3])
C0348080 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0683954 (UMLS CUI [2,3])
C0348080 (UMLS CUI [3,1])
C0521102 (UMLS CUI [3,2])
C2348568 (UMLS CUI [3,3])
C0004936 (UMLS CUI [4,1])
C2348568 (UMLS CUI [4,2])
C1444641 (UMLS CUI [4,3])
C0004936 (UMLS CUI [5,1])
C0521102 (UMLS CUI [5,2])
C0683954 (UMLS CUI [5,3])
C0004936 (UMLS CUI [6,1])
C0521102 (UMLS CUI [6,2])
C2348568 (UMLS CUI [6,3])
C0748872 (UMLS CUI [7,1])
C2348568 (UMLS CUI [7,2])
C1444641 (UMLS CUI [7,3])
C0748872 (UMLS CUI [8,1])
C0521102 (UMLS CUI [8,2])
C0683954 (UMLS CUI [8,3])
C0748872 (UMLS CUI [9,1])
C0521102 (UMLS CUI [9,2])
C2348568 (UMLS CUI [9,3])
Adult Legal capacity Lacking
Item
9. legally incompetent adults, for which reason what so ever.
boolean
C0001675 (UMLS CUI [1,1])
C0683673 (UMLS CUI [1,2])
C0332268 (UMLS CUI [1,3])
Patients | Heart Disease Absent
Item
for the non-cardiac patients:
boolean
C0030705 (UMLS CUI [1])
C0018799 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Cardiovascular Disease
Item
10. a known history of cardiovascular disease.
boolean
C0007222 (UMLS CUI [1])