Informed Consent
Item
joined the study voluntary and signed informed consent form
boolean
C0021430 (UMLS CUI [1])
Age
Item
age 18-75,both genders.
boolean
C0001779 (UMLS CUI [1])
Recurrent Head and Neck Squamous Cell Carcinoma | HEAD NECK CANCER SQUAMOUS CELL METASTATIC
Item
had histologically or cytologically confirmed recurrent or metastatic squamous cell carcinoma of the head and neck
boolean
C4524839 (UMLS CUI [1])
C0744620 (UMLS CUI [2])
Measurable Disease Quantity | Lesion size Measurement conventional | Lesion size Computed Tomography
Item
at least one lesions can be measured,conventional measurements ≥2cm, computed tomography(ct) examination ≥1cm .
boolean
C1513041 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0449453 (UMLS CUI [2,1])
C0242485 (UMLS CUI [2,2])
C0439858 (UMLS CUI [2,3])
C0449453 (UMLS CUI [3,1])
C0040405 (UMLS CUI [3,2])
ECOG performance status
Item
eastern cooperative oncology group(ecog) performance scale 0-2.
boolean
C1520224 (UMLS CUI [1])
Life Expectancy
Item
life expectancy of more than 3 months.
boolean
C0023671 (UMLS CUI [1])
Gender | At risk of unplanned pregnancy Contraceptive method
Item
use of an effective contraceptive method for women when there is a risk of pregnancy during the study.
boolean
C0079399 (UMLS CUI [1])
C3839721 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
Hemoglobin measurement | White Blood Cell Count procedure
Item
haemoglobin≥90g/l ,white blood cell(wbc) ≥3×10^9/l
boolean
C0518015 (UMLS CUI [1])
C0023508 (UMLS CUI [2])
Liver function | Alanine aminotransferase measurement | Aspartate aminotransferase measurement | Serum total bilirubin measurement
Item
hepatic function:alat、asat< 2.5 x uln, tbil< 1.5 x uln
boolean
C0232741 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
C0201899 (UMLS CUI [3])
C1278039 (UMLS CUI [4])
Renal function | Creatinine measurement, serum
Item
renal function: creatinine < 1.5 x uln
boolean
C0232804 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
Anti-EGFR monoclonal antibody therapy
Item
received other anti egfr monoclonal antibody treatment
boolean
C4316122 (UMLS CUI [1])
Study Subject Participation Status | Interventional procedure
Item
participation in other interventional clinical trials within 1 month
boolean
C2348568 (UMLS CUI [1])
C0184661 (UMLS CUI [2])
Pharmacotherapy Other | Operative Surgical Procedure Other
Item
previous received other drug or operative treatment within 6 month
boolean
C0013216 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0543467 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
Pregnancy | Breast Feeding
Item
pregnant or breast-feeding women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Hypersensitivity Serious
Item
history of serious allergic or allergy
boolean
C0020517 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
Lung disease Serious | Disorder of head Serious
Item
patients with the history of serious lung or head disease
boolean
C0024115 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C1290856 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
Cancer Other
Item
other malignant tumor
boolean
C1707251 (UMLS CUI [1])
Neoplasm Except Primary tumor
Item
not primary tumor(except for primary tumor therapy>3months)
boolean
C0027651 (UMLS CUI [1,1])
C0332300 (UMLS CUI [1,2])
C0677930 (UMLS CUI [1,3])