Gender | Breast Carcinoma TNM Breast tumor staging | AC-T Regimen Neoadjuvant
Item
female patients with stage ii or iii (ct1cn+ or ≥t2 any cn, cm0) breast cancer receiving neoadjuvant ac-t
boolean
C0079399 (UMLS CUI [1])
C0678222 (UMLS CUI [2,1])
C0474926 (UMLS CUI [2,2])
C1879500 (UMLS CUI [3,1])
C0600558 (UMLS CUI [3,2])
Measurable Disease | Breast | Lymph nodes
Item
measurable disease (breast and/or lymph nodes)
boolean
C1513041 (UMLS CUI [1])
C0006141 (UMLS CUI [2])
C0024204 (UMLS CUI [3])
HER2 Negative Core needle biopsy | Age
Item
her2 negative core biopsy age ≥18 years
boolean
C2348908 (UMLS CUI [1,1])
C1318309 (UMLS CUI [1,2])
C0001779 (UMLS CUI [2])
WHO performance status scale
Item
who performance status 0-2
boolean
C1298650 (UMLS CUI [1])
Bone Marrow function | White Blood Cell Count procedure | Neutrophil count
Item
adequate bone marrow function : white blood cells (wbcs) ≥3.0 x 109/l, neutrophils
boolean
C0005953 (UMLS CUI [1,1])
C0031843 (UMLS CUI [1,2])
C0023508 (UMLS CUI [2])
C0200633 (UMLS CUI [3])
Platelet Count measurement
Item
≥1.5 x 109/l, platelets ≥100 x 109/l
boolean
C0032181 (UMLS CUI [1])
Liver function | Serum total bilirubin measurement | Alanine aminotransferase measurement | Aspartate aminotransferase measurement | Alkaline phosphatase measurement
Item
adequate liver function: bilirubin ≤1.5 x upper limit of normal (unl) range, alat and/or asat ≤2.5 x unl, alkaline phosphatase ≤5 x unl
boolean
C0232741 (UMLS CUI [1])
C1278039 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
C0201899 (UMLS CUI [4])
C0201850 (UMLS CUI [5])
Renal function | Estimation of creatinine clearance by Cockcroft-Gault formula
Item
adequate renal function: the calculated creatinine clearance should be ≥50 ml/min
boolean
C0232804 (UMLS CUI [1])
C2711451 (UMLS CUI [2])
Patient Available Therapeutic procedure | Patient Available Follow-up
Item
patients must be accessible for treatment and follow-up
boolean
C0030705 (UMLS CUI [1,1])
C0470187 (UMLS CUI [1,2])
C0087111 (UMLS CUI [1,3])
C0030705 (UMLS CUI [2,1])
C0470187 (UMLS CUI [2,2])
C3274571 (UMLS CUI [2,3])
Informed Consent
Item
written informed consent according to the local ethics committee requirements
boolean
C0021430 (UMLS CUI [1])
Quality of life Questionnaire Completion
Item
willing to fill in quality of life questionnaires
boolean
C0034380 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])
Able to read Dutch Language | Able to write Dutch Language
Item
able to read and write in dutch
boolean
C0586740 (UMLS CUI [1,1])
C0376241 (UMLS CUI [1,2])
C0584993 (UMLS CUI [2,1])
C0376241 (UMLS CUI [2,2])
Medical History Invasive carcinoma of breast | Medical History Breast Carcinoma
Item
history of breast cancer (invasive or non-invasive)
boolean
C0262926 (UMLS CUI [1,1])
C0853879 (UMLS CUI [1,2])
C0262926 (UMLS CUI [2,1])
C0678222 (UMLS CUI [2,2])
Malignant Neoplasms | Exception Basal cell carcinoma | Exception Carcinoma in situ of uterine cervix
Item
previous malignancy within 5 years, with exception of a history of a previous basal cell carcinoma of the skin or pre-invasive carcinoma of the cervix.
boolean
C0006826 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0851140 (UMLS CUI [3,2])
Disease Serious | Myocardial Infarction | Sign or Symptom Heart failure | Cardiac Arrhythmia
Item
serious other diseases such as recent myocardial infarction, clinical signs of cardiac failure or clinically significant arrhythmias
boolean
C0012634 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0027051 (UMLS CUI [2])
C3540840 (UMLS CUI [3,1])
C0018801 (UMLS CUI [3,2])
C0003811 (UMLS CUI [4])
Diabetes Mellitus
Item
diabetes mellitus
boolean
C0011849 (UMLS CUI [1])
Body mass index
Item
body mass index (bmi) < 19 kg/m2
boolean
C1305855 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
pregnancy or lactating
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Food Allergy
Item
significant food allergies which would make the subject unable to consume the food provided (ex: nuts or soy)
boolean
C0016470 (UMLS CUI [1])
Metabolic Diseases Affecting Gluconeogenesis | Metabolic Diseases Affecting Adaptation Fasting
Item
any metabolic disorders that may affect gluconeogenesis or adaptation to short fasting periods.
boolean
C0025517 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0017715 (UMLS CUI [1,3])
C0025517 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C0392673 (UMLS CUI [2,3])
C0015663 (UMLS CUI [2,4])
Medical condition Preventing Completion of clinical trial | Mental condition Preventing Completion of clinical trial | Medical condition Preventing Informed Consent | Mental condition Preventing Informed Consent
Item
medical or psychological condition which in the opinion of the investigator would not permit the patient to complete the study or sign meaningful informed consent
boolean
C3843040 (UMLS CUI [1,1])
C1292733 (UMLS CUI [1,2])
C2732579 (UMLS CUI [1,3])
C3840291 (UMLS CUI [2,1])
C1292733 (UMLS CUI [2,2])
C2732579 (UMLS CUI [2,3])
C3843040 (UMLS CUI [3,1])
C1292733 (UMLS CUI [3,2])
C0021430 (UMLS CUI [3,3])
C3840291 (UMLS CUI [4,1])
C1292733 (UMLS CUI [4,2])
C0021430 (UMLS CUI [4,3])