Age | Asthma Disease length
Item
male or female patients aged 12 to 50 years with a diagnosis of asthma for at least 6 months before screening
boolean
C0001779 (UMLS CUI [1])
C0004096 (UMLS CUI [2,1])
C0872146 (UMLS CUI [2,2])
Percent predicted FEV1
Item
baseline fev1 of 60% to >100% of predicted
boolean
C0730561 (UMLS CUI [1])
FEV1 decreased Percentage | Status post Exercise challenge
Item
demonstrate a decrease in fev1 of 15% or greater from baseline after standardized stepped exercise challenge testing
boolean
C4272903 (UMLS CUI [1,1])
C0439165 (UMLS CUI [1,2])
C0231290 (UMLS CUI [2,1])
C1293901 (UMLS CUI [2,2])
Inhaled steroids Low dose Medium
Item
taking a constant dose of low-medium dose inhaled steroids for at least 30 days before screening of either:
boolean
C2065041 (UMLS CUI [1,1])
C0445550 (UMLS CUI [1,2])
C0439536 (UMLS CUI [1,3])
Fluticasone Dose Metered Dose U/day Inhaler | Fluticasone Dose U/day Dry Powder Inhaler
Item
1. fluticasone, 88 - 440 mcg/d via mdi or 100 to 500 mcg/d via dpi
boolean
C0082607 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
C0993596 (UMLS CUI [1,4])
C0082607 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0456683 (UMLS CUI [2,3])
C1967611 (UMLS CUI [2,4])
Beclomethasone Dose U/day
Item
2. beclomethasone hfa 80 to 480 mcg/day
boolean
C0004905 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
Budesonide Dose U/day
Item
3. budesonide dpi 180 to 1200 mcg/ d
boolean
C0054201 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
Flunisolide Dose U/day
Item
4. flunisolide 500 to 2000 mcg/d
boolean
C0060501 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
Flunisolide HFA Dose U/day
Item
5. flunisolide hfa 320 to 640 mcg/d
boolean
C1569761 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
Mometasone Dose U/day
Item
6. mometasone 200 to 800 mcg/d
boolean
C0360564 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
Triamcinolone Acetonide Dose U/day
Item
7. triamcinolone acetonide 300 to 1500 mcg/ d
boolean
C0040866 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
Adrenergic beta-Agonists Long-term Active | CORTICOSTEROIDS FOR SYSTEMIC USE | Combined Modality Therapy | inhaled steroids
Item
patients already on labas, systemic corticosteroids, or other combination inhaled steroids/laba medications.
boolean
C0001644 (UMLS CUI [1,1])
C0443252 (UMLS CUI [1,2])
C0205177 (UMLS CUI [1,3])
C3653708 (UMLS CUI [2])
C0009429 (UMLS CUI [3])
C2065041 (UMLS CUI [4])
Exercise challenge Completion Unable | Etiology Constraint Physical
Item
patients not able to safely complete an exercise challenge due to physical constraints outside of their respiratory status.
boolean
C1293901 (UMLS CUI [1,1])
C0205197 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
C0015127 (UMLS CUI [2,1])
C0443288 (UMLS CUI [2,2])
C0205485 (UMLS CUI [2,3])
Pregnancy | Pregnancy, Planned
Item
patients who are pregnant or plan to become pregnant during the study period.
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
Allergic Reaction Formoterol | Budesonide allergy
Item
patients with a history of hypersensitivity reaction to either formoterol or budesonide.
boolean
C1527304 (UMLS CUI [1,1])
C0060657 (UMLS CUI [1,2])
C0571620 (UMLS CUI [2])
Disease Study Subject Participation Status At risk | Disease Influence Research results | Disease Study Subject Participation Status Limited
Item
patients with any significant disease or disorder which, in the opinion of the investigator, may either put the patient at risk because of participation in the study, or influence the results of the study, or the patient's ability to participate in the study.
boolean
C0012634 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C1444641 (UMLS CUI [1,3])
C0012634 (UMLS CUI [2,1])
C4054723 (UMLS CUI [2,2])
C0683954 (UMLS CUI [2,3])
C0012634 (UMLS CUI [3,1])
C2348568 (UMLS CUI [3,2])
C0439801 (UMLS CUI [3,3])
Hospitalization Planned
Item
patients with planned hospitalization during the study
boolean
C0019993 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
Tobacco use | Smoking cigarettes: ____ pack-years history
Item
current smokers or those with a history of 10 pack years of tobacco use or more.
boolean
C0543414 (UMLS CUI [1])
C2230126 (UMLS CUI [2])