Clinical Trial Subject Unique Identifier
Item
Subject Identifier
integer
C2348585 (UMLS CUI [1])
Date of visit
Item
Visit Date
date
C1320303 (UMLS CUI [1])
Body Height
Item
Height
integer
C0005890 (UMLS CUI [1])
Body Weight
Item
Weight
float
C0005910 (UMLS CUI [1])
Body mass index
Item
Body mass index
float
C1305855 (UMLS CUI [1])
Vital Signs Date
Item
Date
date
C2826644 (UMLS CUI [1])
Item
Planned Relative Time
text
C0518766 (UMLS CUI [1,1])
C0439564 (UMLS CUI [1,2])
C1301732 (UMLS CUI [1,3])
Code List
Planned Relative Time
Vital Signs Time
Item
Actual Time
time
C2826762 (UMLS CUI [1])
Systolic Pressure
Item
Blood Pressure - Systolic
integer
C0871470 (UMLS CUI [1])
Diastolic blood pressure
Item
Blood Pressure - Diastolic
integer
C0428883 (UMLS CUI [1])
Item
Subject Position
text
C0518766 (UMLS CUI [1,1])
C1262869 (UMLS CUI [1,2])
Code List
Subject Position
Heart rate
Item
Heart Rate
integer
C0018810 (UMLS CUI [1])
Physical Examination, Assessment Date
Item
Date of Assessment
date
C0031809 (UMLS CUI [1,1])
C2985720 (UMLS CUI [1,2])
Item
Physical Examination
text
C0031809 (UMLS CUI [1,1])
C0678852 (UMLS CUI [1,2])
Code List
Physical Examination
CL Item
Hair and skin (1)
CL Item
Ears, Nose and Throat (4)
CL Item
Cardiovascular (7)
CL Item
Musculoskeletal (12)
CL Item
Neurological (13)
CL Item
Mental status (14)
Item
Result
text
C0031809 (UMLS CUI [1,1])
C0456984 (UMLS CUI [1,2])
Physical Examination, Comment
Item
Comment
text
C0031809 (UMLS CUI [1,1])
C0947611 (UMLS CUI [1,2])
Allen test
Item
Was an Allen's Test performed?
boolean
C0231664 (UMLS CUI [1])
Alcohol consumption
Item
Does the subject consume alcohol?
boolean
C0001948 (UMLS CUI [1])
Alcohol consumption, alcohol units/week
Item
If Yes, record the average number of units of alcohol consumed per week
integer
C0001948 (UMLS CUI [1,1])
C0560579 (UMLS CUI [1,2])
Urine drug screening, Ethanol measurement, Sampling, Date in time, Time
Item
Date and time of sample taken
datetime
C0202274 (UMLS CUI [1,1])
C0202304 (UMLS CUI [1,2])
C0870078 (UMLS CUI [1,3])
C0011008 (UMLS CUI [1,4])
C0040223 (UMLS CUI [1,5])
Item
Cocaine
text
C0202274 (UMLS CUI [1,1])
C0009170 (UMLS CUI [1,2])
Item
Amphetamines
text
C0202274 (UMLS CUI [1,1])
C0002667 (UMLS CUI [1,2])
Item
Benzodiazepines
text
C0202274 (UMLS CUI [1,1])
C0005064 (UMLS CUI [1,2])
Code List
Benzodiazepines
Item
Cannabinoids
text
C0202274 (UMLS CUI [1,1])
C0936079 (UMLS CUI [1,2])
Item
Opiates
text
C0202274 (UMLS CUI [1,1])
C0376196 (UMLS CUI [1,2])
Urine drug screening, Barbiturates
Item
Barbiturates
text
C0202274 (UMLS CUI [1,1])
C0004745 (UMLS CUI [1,2])
Item
Cotinine
text
C0202274 (UMLS CUI [1,1])
C0202363 (UMLS CUI [1,2])
Item
Alcohol
text
C0202304 (UMLS CUI [1])
Serologic tests, Sampling, Date in time
Item
Date sample taken
date
C0036743 (UMLS CUI [1,1])
C0870078 (UMLS CUI [1,2])
C0011008 (UMLS CUI [1,3])
Item
HIV antibody
text
C0036743 (UMLS CUI [1,1])
C0459958 (UMLS CUI [1,2])
Item
Hepatitis B surface antigen
text
C0036743 (UMLS CUI [1,1])
C0019168 (UMLS CUI [1,2])
Code List
Hepatitis B surface antigen
Item
Hepatitis C antibody
text
C0036743 (UMLS CUI [1,1])
C0201487 (UMLS CUI [1,2])
Code List
Hepatitis C antibody
Mini International Neuropsychiatric Interview
Item
Has the M.I.N.I. assessment been performed?
boolean
C4505426 (UMLS CUI [1])
Laboratory Procedures, Hematology finding, Sampling, Date in time
Item
Date Sample Taken
date
C0022885 (UMLS CUI [1,1])
C0474523 (UMLS CUI [1,2])
C0870078 (UMLS CUI [1,3])
C0011008 (UMLS CUI [1,4])
Laboratory Procedures, Hematology finding, Sampling, Time
Item
Actual Time
time
C0022885 (UMLS CUI [1,1])
C0474523 (UMLS CUI [1,2])
C0870078 (UMLS CUI [1,3])
C0040223 (UMLS CUI [1,4])
Laboratory Procedures, Chemistry, Clinical, Sampling, Date in time
Item
Date Sample Taken
date
C0022885 (UMLS CUI [1,1])
C0008000 (UMLS CUI [1,2])
C0870078 (UMLS CUI [1,3])
C0011008 (UMLS CUI [1,4])
Laboratory Procedures, Chemistry, Clinical, Sampling, Time
Item
Actual Time
time
C0022885 (UMLS CUI [1,1])
C0008000 (UMLS CUI [1,2])
C0870078 (UMLS CUI [1,3])
C0040223 (UMLS CUI [1,4])
Urinalysis, Sampling, Date in time
Item
Date Sample Taken
date
C0042014 (UMLS CUI [1,1])
C0870078 (UMLS CUI [1,2])
C0011008 (UMLS CUI [1,3])
Urinalysis, Sampling, Time
Item
Actual Time
time
C0042014 (UMLS CUI [1,1])
C0870078 (UMLS CUI [1,2])
C0040223 (UMLS CUI [1,3])
Laboratory Procedures, Renal function, Blood, Sampling, Date in time
Item
Date Sample Taken
date
C0022885 (UMLS CUI [1,1])
C0232804 (UMLS CUI [1,2])
C0005767 (UMLS CUI [1,3])
C0870078 (UMLS CUI [1,4])
C0011008 (UMLS CUI [1,5])
Laboratory Procedures, Renal function, Blood, Sampling, Time
Item
Actual Time
time
C0022885 (UMLS CUI [1,1])
C0232804 (UMLS CUI [1,2])
C0005767 (UMLS CUI [1,3])
C0870078 (UMLS CUI [1,4])
C0040223 (UMLS CUI [1,5])
Laboratory Procedures, Renal function, Urine, Sampling, Date in time
Item
Date Sample Taken
date
C0022885 (UMLS CUI [1,1])
C0232804 (UMLS CUI [1,2])
C0042036 (UMLS CUI [1,3])
C0870078 (UMLS CUI [1,4])
C0011008 (UMLS CUI [1,5])
Laboratory Procedures, Renal function, Urine, Sampling, Time
Item
Actual Time
time
C0022885 (UMLS CUI [1,1])
C0232804 (UMLS CUI [1,2])
C0042036 (UMLS CUI [1,3])
C0870078 (UMLS CUI [1,4])
C0040223 (UMLS CUI [1,5])
Item
ECG Number
text
C0430456 (UMLS CUI [1,1])
C0237753 (UMLS CUI [1,2])
12 lead ECG, Start Date
Item
Start Date of ECG
date
C0430456 (UMLS CUI [1,1])
C0808070 (UMLS CUI [1,2])
Item
Planned Relative Time
text
C0430456 (UMLS CUI [1,1])
C0439564 (UMLS CUI [1,2])
C1301732 (UMLS CUI [1,3])
Code List
Planned Relative Time
12 lead ECG, Start time
Item
Start Time of ECG
time
C0430456 (UMLS CUI [1,1])
C1301880 (UMLS CUI [1,2])
12 lead ECG, Heart rate
Item
Heart Rate
integer
C0430456 (UMLS CUI [1,1])
C0018810 (UMLS CUI [1,2])
12 lead ECG, PR interval
Item
PR Interval
integer
C0430456 (UMLS CUI [1,1])
C0429087 (UMLS CUI [1,2])
12 lead ECG, QRS complex duration
Item
QRS Duration
integer
C0430456 (UMLS CUI [1,1])
C0429025 (UMLS CUI [1,2])
12 lead ECG, QT interval
Item
Uncorrected QT Interval
integer
C0430456 (UMLS CUI [1,1])
C1287082 (UMLS CUI [1,2])
12 lead ECG, Electrocardiogram QT corrected interval
Item
QTc Interval
integer
C0430456 (UMLS CUI [1,1])
C0855331 (UMLS CUI [1,2])
Item
Result of the ECG
text
C0430456 (UMLS CUI [1,1])
C1274040 (UMLS CUI [1,2])
Code List
Result of the ECG
CL Item
Abnormal - not clinically significant (2)
CL Item
Abnormal - clinically significant (3)
CL Item
No result (not available) (4)
Holter Electrocardiography, Start Date
Item
Start Date of Holter
date
C0013801 (UMLS CUI [1,1])
C0808070 (UMLS CUI [1,2])
Holter Electrocardiography, Start time
Item
Start time of Holter
time
C0013801 (UMLS CUI [1,1])
C1301880 (UMLS CUI [1,2])
Holter Electrocardiography, End Date
Item
Stop date of Holter
date
C0013801 (UMLS CUI [1,1])
C0806020 (UMLS CUI [1,2])
Holter Electrocardiography, End time
Item
Stop time of Holter
time
C0013801 (UMLS CUI [1,1])
C1522314 (UMLS CUI [1,2])
Item
Interpretation of Holter
text
C0013801 (UMLS CUI [1,1])
C4086187 (UMLS CUI [1,2])
Code List
Interpretation of Holter
CL Item
Abnormal - Not clinically significant (2)
CL Item
Abnormal - Clinically significant (3)
CL Item
Unable to evaluate (5)
Item
Holter monitoring method
text
C0013801 (UMLS CUI [1,1])
C0871511 (UMLS CUI [1,2])
Code List
Holter monitoring method
CL Item
12 Lead 1000Hz (1)
CL Item
12 lead 180Hz (2)
CL Item
3 Lead 180 Hz (3)
CL Item
4 Lead 0.05-40 Hz (6)
CL Item
6 Lead 0.05-40 Hz (7)
CL Item
7 Lead 0.05-100 Hz-3dB (8)
CL Item
7 Lead 3 channel 133 Hz (9)
CL Item
2 Lead 200 Hz (10)
Eligibility Determination
Item
Did the subject meet all the entry criteria?
boolean
C0013893 (UMLS CUI [1])
Health status
Item
Healthy as determined by a reasonable and experienced physician, based on a medical evaluation including medical history, physical examination, laboratory tests and cardiac monitoring. A subject with a clinical abnormality or laboratory parameters outside the reference range for the population being studied may be included only if the Investigator and the GSK Medical Monitor agree that the finding is unlikely to introduce additional risk factors and will not interfere with the study procedures. Subjects with renal monitoring test values outside of the ranges in Appendix 2 (of the protocol) should always be excluded from enrolment.
boolean
C0018759 (UMLS CUI [1])
Gender; Age
Item
Male subject between 35 and 55 years of age inclusive, at the time of signing the informed consent.
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Contraceptive methods
Item
Male subjects must agree to use one of the contraception methods listed in Section 8.1 (of the protocol). This criterion must be followed from the time the first administration of [11C]GSK1034702 until completion of the study and for 4 months after dosing.
boolean
C0700589 (UMLS CUI [1])
Body Weight; Body mass index
Item
Body weight >= 50kg and BMI within the range 19.0 - 29.0 kg/m2 (inclusive).
boolean
C0005910 (UMLS CUI [1])
C1305855 (UMLS CUI [2])
Informed Consent
Item
Capable of giving written informed consent, which includes compliance with the requirements and restrictions listed in the consent form.
boolean
C0021430 (UMLS CUI [1])
Allen test, Negative finding
Item
Adequate collateral flow to the radial and ulnar arteries in both hands as determined by the Allen's test.
boolean
C0231664 (UMLS CUI [1,1])
C1513916 (UMLS CUI [1,2])
Drug screen; Ethanol measurement
Item
A positive pre-study drug/alcohol screen. A minimum list of drug that will be screened for include amphetamines, barbiturates, cocaine, opiates, cannabinoids and benzodiazepines.
boolean
C0373483 (UMLS CUI [1])
C0202304 (UMLS CUI [2])
Urine cotinine measurement, Tobacco use
Item
Urinary cotinine levels indicate of smoking or history or regular use of tobacco- or nicotine-containing products within 6 months prior to screening.
boolean
C1278256 (UMLS CUI [1,1])
C0543414 (UMLS CUI [1,2])
Alcohol consumption
Item
History of alcohol consumption within 6 months of the study defined as: - An average weekly intake of > 21 Units for males or > 14 units for females. One unit is equivalent to 8g of alcohol: a half-pint (240mL) of beer, 1 glass (125mL) of wine or 1 (25 mL) measure of spirits.
boolean
C0001948 (UMLS CUI [1])
Hepatitis B surface antigen positive; Hepatitis C antibody positive
Item
A positive pre-study Hepatitis B surface antigen (HBsAg) or positive Hepatitis C antibody result within 3 months of screening.
boolean
C0149709 (UMLS CUI [1])
C0281863 (UMLS CUI [2])
HIV antibody positive
Item
A positive test for human immunodeficiency virus (HIV) antibody.
boolean
C0920548 (UMLS CUI [1])
Electrocardiogram, Abnormality
Item
A screening ECG with a QTc value of >450msec (triplicate ECGs) and/or a PR interval outside the range 120 to 200msec (triplicate ECGs) or an ECG that is not suitable for QT measurements (e.g. poorly defined termination of the T-wave)
boolean
C0013798 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
Heart rate; Systolic Pressure; Diastolic blood pressure; Hypotension, Orthostatic
Item
Puls rate <50 or >90 BPM OR a systolic BP > 140 or <90 OR a diastolic BP >90 0r <60 OR orthostatic hypotension (reduction of systolic BP >10mmHg).
boolean
C0018810 (UMLS CUI [1])
C0871470 (UMLS CUI [2])
C0428883 (UMLS CUI [3])
C0020651 (UMLS CUI [4])
Long QT Syndrome; Cardiac conduction abnormality; Sudden death, Unexplained; Syncope, Unexplained; Heart Diseases
Item
History of long QT syndrome (personal or family) or other cardiac conduction disorder, a history of sudden unexplained death or unexplained syncope in a first degree relative or other clinically significant cardiac disease.
boolean
C0023976 (UMLS CUI [1])
C1842820 (UMLS CUI [2])
C0011071 (UMLS CUI [3,1])
C4288071 (UMLS CUI [3,2])
C0039070 (UMLS CUI [4,1])
C4288071 (UMLS CUI [4,2])
C0018799 (UMLS CUI [5])
Cardiovascular Diseases
Item
Subjects with current or past disease of cardiovascular disease including but not limited to hypertension, cardiac arrhythmias and/or risk factors for coronary artery disease.
boolean
C0007222 (UMLS CUI [1])
Gastrointestinal Diseases; Operative Surgical Procedures
Item
Current or recent (without one year) gastrointestinal disease; a history of malabsorption, oesophageal reflux, irritable bowel syndrome; frequent (more than once a week) occurrence of heartburn; or any surgical intervention (e.g., cholecystectomy) which would be expected to influence the absorption of drugs.
boolean
C0017178 (UMLS CUI [1])
C0543467 (UMLS CUI [2])
Respiration Disorders
Item
Subjects who have current respiratory or a history of respiratory problems (e.g. asthma or allergies, including childhood conditions).
boolean
C0035204 (UMLS CUI [1])
Renal function, Abnormality
Item
Subjects who have current renal or history of clinically significant renal abnormalities.
boolean
C0232804 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
nervous system disorder
Item
History or presence of a neurological diagnosis (not limited to but including for example, stroke, traumatic brain injury, epilepsy, space occupying lesions, multiple sclerosis, Parkinson's disease, vascular dementia, transient ischemic attack, schizophrenia, major depression etc) that may influence the outcome or analysis of the scan results.
boolean
C0027765 (UMLS CUI [1])
Psychiatric History
Item
Any previous or current psychiatric history, as assessed by the M.I.N.I
boolean
C0748059 (UMLS CUI [1])
Suicidal behavior; Active suicidal ideation
Item
Any history of suicidal behavior or an suicidal ideation of type 4 or 5 on the CSSRS in the last month.
boolean
C3641604 (UMLS CUI [1])
C0749133 (UMLS CUI [2])
Mental handicap; legal capacity, Lacking
Item
Subject is mentally or legally incapacitated.
boolean
C1306341 (UMLS CUI [1])
C0683673 (UMLS CUI [2,1])
C0332268 (UMLS CUI [2,2])
Pharmaceutical Preparations
Item
Use of prescription or non-prescription drugs, including vitamins, herbal or dietary supplements (including St John's Wort) within 7 days (or 14 days if the drug is a potential enzyme inducer) or 5 half-lives (whichever is longer) prior to the first dose of study medication, unless in the opinion of the Investigator and GSK Medical Monitor the medication will not interfere with the study procedures or compromise subject safety.
boolean
C0013227 (UMLS CUI [1])
Red wine, Citrus aurantium, Grapefruit, Grapefruit juice
Item
Consumption of red wine, seville oranges, grapefruit or grapefruit juice from 7 days prior to the first dose of study medication.
boolean
C0349371 (UMLS CUI [1])
C0330922 (UMLS CUI [2])
C0995150 (UMLS CUI [3])
C0452456 (UMLS CUI [4])
Blood Donation
Item
Where participation in the study would result in donation of blood or blood products in excess of 500mL within a 56 day period
boolean
C0005794 (UMLS CUI [1])
Experimental drug, Hypersensitivity; Hypersensitivity, Other
Item
History of sensitivity to any of the study medications, or components thereof or a history or other allergy that, in the opinion of the investigator or GSK Medical Monitor, contraindicates their participation.
boolean
C0304229 (UMLS CUI [1,1])
C0020517 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
Study Subject Participation Status
Item
The subject has participated in a clinical trial and has received an IP within the following time period prior to the fist dosing day in the current study: 3 months, 5 half-lives or twice the duration of the biological effect of the IP (whichever is longer).
boolean
C2348568 (UMLS CUI [1])
Pharmaceutical Preparations
Item
Exposure to more than three new chemical entities within 12 months prior to the first dosing day.
boolean
C0013227 (UMLS CUI [1])
Protocol Compliance
Item
Unwillingness or inability to follow the procedures outlined in the protocol.
boolean
C0525058 (UMLS CUI [1])
Extensive Radiation
Item
Previous inclusion in a research and/or medical protocol involving nuclear medicine, PET or radiological investigations with significant radiation burden (a significant radiation burden being defined as >10mSv in addition to natural background in the previous 3 years). Or worked as a welder , metal worker or machinist.
boolean
C1517030 (UMLS CUI [1])
Claustrophobia; Magnetic Resonance Imaging, Unable; Positron emission tomography unit, Unable
Item
History of, or suffers from, claustrophobia or feels that he will be unable to lie still on his back in the PET or MRI scanner for a period of 1-2 h.
boolean
C0008909 (UMLS CUI [1])
C0024485 (UMLS CUI [2,1])
C1299582 (UMLS CUI [2,2])
C0182349 (UMLS CUI [3,1])
C1299582 (UMLS CUI [3,2])
Artificial cardiac pacemaker; presence of metallic device / implant
Item
Presence of a cardiac pacemaker or other electronic device or ferromagnetic metal foreign bodies as assessed by a standard pre-MRI questionnaire
boolean
C0030163 (UMLS CUI [1])
C3693688 (UMLS CUI [2])
12 lead ECG, Numbers
Item
ECG Number
integer
C0430456 (UMLS CUI [1,1])
C0237753 (UMLS CUI [1,2])
12 lead ECG, Date in time
Item
Date of ECG
date
C0430456 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
12 lead ECG, Time
Item
Time of ECG
time
C0430456 (UMLS CUI [1,1])
C0040223 (UMLS CUI [1,2])
Item
Rhythm
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0199556 (UMLS CUI [1,3])
CL Item
Sinus bradycardia (1)
CL Item
Sinus bradycardia (heart rate 40-50 beats/min) (2)
CL Item
Sinus bradycardia (heart rate 30-39 beats/min) (3)
CL Item
Sinus bradycardia (heart rate < 30 beats/min) (4)
CL Item
Sinus tachycardia (heart rate >100 beats/min) (6)
CL Item
Ectopic supraventricular beats (7)
CL Item
Ectopic supraventricular rhythm (8)
CL Item
Wandering atrial pacemaker (9)
CL Item
Multifocal atrial tachycardia (Wandering atrial pacemaker with heart rate >100 beats/min) (10)
CL Item
Supraventricular tachycardia (heart rate >100 beats/min) (11)
CL Item
Atrial flutter (12)
CL Item
Atrial fibrillation (13)
CL Item
Junctional rhythm (heart rate ≤100 beats/min) (14)
CL Item
Junctional rhythm (15)
CL Item
Junctional tachycardia (heart rate > 100beats/min) (16)
CL Item
Ectopic ventricular beats (17)
CL Item
Ventricular couplets (18)
CL Item
Electrical alternans (21)
CL Item
R on T phenomenon (22)
CL Item
Ventricular fibrillation (23)
CL Item
Idioventricular rhythm (heart rate < 100 beats/min) (24)
CL Item
Sustained ventricular tachycardia (25)
CL Item
Non-sustained ventricular tachycardia (26)
CL Item
Wide QRS Tachycardia (diagnosis unknown) (27)
CL Item
Ventricular tachycardia (28)
CL Item
Monomorphic ventricular tachycardia (29)
CL Item
Torsades de Pointes (Polymorphic ventricular tachycardia with prolonged QT) (30)
CL Item
Polymorphic (sustained and non-sustained) ventricular tachycardia (31)
CL Item
Artificial pacemaker (32)
CL Item
Other abnormal rhythm (33)
12 lead ECG, Abnormality, Rhythm
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0199556 (UMLS CUI [1,3])
Item
P-Wave and QRS Morphology
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C2216025 (UMLS CUI [1,3])
C0429098 (UMLS CUI [1,4])
Code List
P-Wave and QRS Morphology
CL Item
Left atrial abnormality (P mitrale) (1)
CL Item
Right atrial abnormality (P pulmonale) (2)
CL Item
Right ventricular hypertrophy (3)
CL Item
Intraatrial conduction delay (4)
CL Item
Increased voltage consistent with left ventricular hypertrophy (5)
CL Item
Other morphology (6)
12 lead ECG, Abnormality, electrocardiogram: P wave shifting morphology; Electrocardiogram QRS complex
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C2216025 (UMLS CUI [1,3])
C0429098 (UMLS CUI [1,4])
Item
Conduction
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0232217 (UMLS CUI [1,3])
CL Item
First degree AV block (PR interval > 200 msec) (1)
CL Item
Short PR interval (2)
CL Item
Second degree AV block (Mobitz type 1) (3)
CL Item
Second degree AV block (Mobitz type 2) (4)
CL Item
Third degree AV block (6)
CL Item
Left axis deviation (QRS axis more negative than -30°) (7)
CL Item
Right axis deviation (QRS axis more positive than +110°) (8)
CL Item
Incomplete right bundle branch block (9)
CL Item
Incomplete left bundle branch block (10)
CL Item
Right bundle branch block (11)
CL Item
Left anterior hemiblock (synonymous to left anterior fascicular block) (12)
CL Item
Left posterior hemiblock (synonymous to left posterior fascicular block) (13)
CL Item
Left bundle branch block (14)
CL Item
Bifascicular block (15)
CL Item
Non-specific intraventricular conduction delay (QRS ≥ 120 msec) (16)
CL Item
Accessory pathway (Wolff-Parkinson White, Lown-Ganong-Levine) (17)
CL Item
Prolonged QT interval (18)
CL Item
QT/QTc prolongation ≥ 500 msec (19)
CL Item
AV dissociation (20)
CL Item
Other conduction (21)
12 lead ECG, Abnormality, Cardiac Conduction
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0232217 (UMLS CUI [1,3])
Item
Myocardial Infarction
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0027051 (UMLS CUI [1,3])
Code List
Myocardial Infarction
CL Item
Myocardial infarction, old (1)
CL Item
Myocardial infarction, anterior (2)
CL Item
Myocardial infarction, lateral (3)
CL Item
Myocardial infarction, posterior (4)
CL Item
Myocardial infarction, inferior (5)
CL Item
Myocardial infarction, septal (6)
CL Item
Myocardial infarction, Non-Q wave (7)
CL Item
Other myocardial infarction (8)
12 lead ECG, Abnormality, Myocardial Infarction
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0027051 (UMLS CUI [1,3])
Item
Depolarisation/Repolarisation (QRS-T)
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C1331539 (UMLS CUI [1,3])
C0948857 (UMLS CUI [1,4])
Code List
Depolarisation/Repolarisation (QRS-T)
CL Item
Non-specific ST-T changes (1)
CL Item
J point elevation (2)
CL Item
ST elevation-pericarditis (4)
CL Item
ST depression (5)
CL Item
U waves abnormal (6)
CL Item
T wave inversion (7)
CL Item
T wave peaked (8)
CL Item
T waves biphasic (10)
CL Item
Notched T-waves (11)
CL Item
Low QRS voltage (12)
CL Item
T-wave flattening/inversion (13)
CL Item
Other depolarisation/repolarisation (14)
12 lead ECG, Abnormality, Ventricular Depolarization [PE], Electrocardiogram repolarisation abnormality
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C1331539 (UMLS CUI [1,3])
C0948857 (UMLS CUI [1,4])
Item
Other Abnormalities
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
Code List
Other Abnormalities
CL Item
Other abnormalities (1)
12 lead ECG, Abnormality, Other
Item
Comment
text
C0430456 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
Holter Electrocardiography, Start Date
Item
Start Date of Holter
date
C0013801 (UMLS CUI [1,1])
C0808070 (UMLS CUI [1,2])
Holter Electrocardiography, End Date
Item
Stop Date of Holter
date
C0013801 (UMLS CUI [1,1])
C0806020 (UMLS CUI [1,2])
Holter Electrocardiography, Start Time
Item
Start Time of Holter
date
C0013801 (UMLS CUI [1,1])
C1301880 (UMLS CUI [1,2])
Holter Electrocardiography, End Time
Item
Stop Time of Holter
time
C0013801 (UMLS CUI [1,1])
C1522314 (UMLS CUI [1,2])
Item
Record clinically significant abnormalities below
text
C0013801 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
Code List
Record clinically significant abnormalities below
CL Item
Sinus bradycardia (50-59 beats/min) (1)
CL Item
Sinus bradycardia (40-49 beats/min) (2)
CL Item
Sinus bradycardia (30-39 beats/min) (3)
CL Item
Sinus bradycardia (< 30 beats/min) (4)
CL Item
Sinus tachycardia (>100 beats/min) (6)
CL Item
Ectopic supraventricular beats (7)
CL Item
Ectopic supraventricular rhythm (8)
CL Item
Wandering atrial pacemaker (9)
CL Item
Multifocal atrial tachycardia (wandering atrial pacemaker w/rate >100 beats/min) (10)
CL Item
Non-sustained supraventricular tachycardia (>100 beats/min, 3-30 beats)) (11)
CL Item
Sustained supraventricular tachycardia (>100 beats/min, >30 beats)) (12)
CL Item
Atrial flutter (13)
CL Item
Atrial fibrillation (14)
CL Item
Junctional rhythm (<=100beats/min, defined by narrow QRS complexes) (15)
CL Item
Junctional tachycardia (heart rate >100 beats/min) (16)
CL Item
Ventricular premature depolarisation (17)
CL Item
Ventricular couplets (18)
CL Item
Electrical alternans (21)
CL Item
R on T phenomenon (22)
CL Item
Ventricular fibrillation (23)
CL Item
Idioventricular rhythm (<= 100 beats/min, defined by wide QRS complexes) (24)
CL Item
Non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats) (25)
CL Item
Sustained ventricular tachycardia (>100 beats/min, >30 beats) (26)
CL Item
Wide QRS Tachycardia (diagnosis unknown) (27)
CL Item
Monomorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats) (28)
CL Item
Monomorphic sustained ventricular tachycardia (>100 beats/min, >30 beats) (29)
CL Item
Polymorphic non-sustained ventricular tachycardia (>100 beats/min, 3-30 beats) (30)
CL Item
Polymorphic sustained ventricular tachycardia (>100 beats/min, >30 beats) (31)
CL Item
Torsades de Pointes (TdP) (32)
CL Item
First degree AV block (PR interval > 200 msec) (34)
CL Item
Short PR interval (35)
CL Item
Second degree AV block (Mobitz type 1) (36)
CL Item
Second degree AV block (Mobitz type 2) (37)
CL Item
2:1 AV block (38)
CL Item
Third degree AV block (39)
CL Item
Left axis deviation (QRS axis more negative than -30 degrees) (40)
CL Item
Right axis deviation (QRS axis more positive than +110 degrees) (41)
CL Item
Incomplete right bundle branch block (42)
CL Item
Incomplete left bundle branch block (43)
CL Item
Right bundle branch block (44)
CL Item
Left anterior hemiblock (45)
CL Item
Left posterior hemiblock (46)
CL Item
Left bundle branch block (47)
CL Item
Bifascicular block (48)
CL Item
Non-specific intraventricular conduction delay (QRS ≥ 120 msec) (49)
CL Item
Accessory pathway (Wolff-Parkinson White, Lown-Ganong-Levine) (50)
CL Item
QTc prolongation ≥ 500 msec (51)
CL Item
AV dissociation (52)
CL Item
Myocardial infarction, old (53)
CL Item
Myocardial infarction, Non-Q wave (54)
CL Item
Non-specific ST-T changes (55)
CL Item
J point elevation (56)
CL Item
ST elevation (57)
CL Item
ST depression (58)
CL Item
ST segment abnormally (59)
CL Item
T wave inversion (61)
CL Item
T wave peaked (62)
CL Item
T waves biphasic (63)
CL Item
T waves flat (64)
CL Item
Notched T-waves (65)
CL Item
Low QRS voltage (66)
CL Item
T wave abnormality (67)
Holter Eletrocardiography, Abnormality, Electrocardiogram, rhythm
Item
Other abnormal rhythm, Comment
text
C0013801 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0199556 (UMLS CUI [1,3])
Holter Eletrocardiography, Abnormality, electrocardiogram: P wave shifting morphology, Electrocardiogram QRS complex
Item
Other morphology, Comment
text
C0013801 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C2216025 (UMLS CUI [1,3])
C0429098 (UMLS CUI [1,4])
Holter Eletrocardiography, Abnormality, Cardiac conduction
Item
Other conduction, Comment
text
C0013801 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0232217 (UMLS CUI [1,3])
Holter Eletrocardiography, Abnormality, Ventricular Depolarization, Electrocardiogram repolarisation abnormality
Item
Other depolarisation/repolarization, Comment
text
C0013801 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C1331539 (UMLS CUI [1,3])
C0948857 (UMLS CUI [1,4])
Holter Eletrocardiography, Abnormality, Other, Comment
Item
Other abnormality/Cardiologist comments
text
C0013801 (UMLS CUI [1,1])
C1704258 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0947611 (UMLS CUI [1,4])