Informed Consent | Informed Consent Genotype determination
Item
signature of a written informed consent, included informed consent on genotype analysis.
boolean
C0021430 (UMLS CUI [1])
C0021430 (UMLS CUI [2,1])
C1285573 (UMLS CUI [2,2])
Patient Hypertensive Newly Diagnosed | Patient untreated
Item
naive hypertensive patient (new diagnosed patient, never treated before).
boolean
C0030705 (UMLS CUI [1,1])
C0857121 (UMLS CUI [1,2])
C1518321 (UMLS CUI [1,3])
C0030705 (UMLS CUI [2,1])
C0332155 (UMLS CUI [2,2])
Hypertensive disease Mild | Hypertensive disease Moderate | Systolic Pressure | Diastolic blood pressure
Item
documented mild to moderate arterial hypertension: sbp comprised between 140 and 169 mmhg and dbp between 85 and 100 mmhg;
boolean
C0020538 (UMLS CUI [1,1])
C2945599 (UMLS CUI [1,2])
C0020538 (UMLS CUI [2,1])
C0205081 (UMLS CUI [2,2])
C0871470 (UMLS CUI [3])
C0428883 (UMLS CUI [4])
Genotype Mutated Quantity | Genotype Combination
Item
presence of at least one mutated genotype or combination of genotypes corresponding to the list provided in the protocol.
boolean
C0017431 (UMLS CUI [1,1])
C1705285 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0017431 (UMLS CUI [2,1])
C0205195 (UMLS CUI [2,2])
Secondary hypertension | Hypertension, severe | Malignant Hypertension
Item
known causes of secondary or severe or malignant hypertension;
boolean
C0155616 (UMLS CUI [1])
C4013784 (UMLS CUI [2])
C0020540 (UMLS CUI [3])
Kidney Disease | Liver disease
Item
significant renal or hepatic disease;
boolean
C0022658 (UMLS CUI [1])
C0023895 (UMLS CUI [2])
Heart Diseases | Requirement Pharmacotherapy Illicit | Myocardial Infarction
Item
cardiac disease requiring prohibited pharmacological treatment or history of myocardial infarction within the last 6 months;
boolean
C0018799 (UMLS CUI [1])
C1514873 (UMLS CUI [2,1])
C0013216 (UMLS CUI [2,2])
C0332266 (UMLS CUI [2,3])
C0027051 (UMLS CUI [3])
Atrial Fibrillation | Complete bundle branch block
Item
atrial fibrillation or complete ventricle bundle branch block;
boolean
C0004238 (UMLS CUI [1])
C3544314 (UMLS CUI [2])
First degree atrioventricular block
Item
first degree av-block exceeding 240 msec;
boolean
C0085614 (UMLS CUI [1])
ECG left ventricle hypertrophy
Item
electrocardiographic evidence of left ventricular hypertrophy;
boolean
C0232306 (UMLS CUI [1])
Pregnancy | Breast Feeding | Childbearing Potential Contraceptive Agents Absent | Childbearing Potential Contraceptive method Double Absent
Item
pregnant or nursing women or women of childbearing potential not taking anti-contraceptive medication or not utilizing a double contraceptive method;
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0009871 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])
C3831118 (UMLS CUI [4,1])
C0700589 (UMLS CUI [4,2])
C0205173 (UMLS CUI [4,3])
C0332197 (UMLS CUI [4,4])
Pharmaceutical Preparations Affecting Blood Pressure
Item
concomitant therapy with medications that may affect blood pressure;
boolean
C0013227 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0005823 (UMLS CUI [1,3])
Diabetes Mellitus | Plasma fasting glucose measurement
Item
diabetes mellitus (fasting plasma glucose > 125 mg/dl);
boolean
C0011849 (UMLS CUI [1])
C0583513 (UMLS CUI [2])
Statin therapy
Item
statins treatment.
boolean
C1278454 (UMLS CUI [1])