Adult | Age
Item
adult subjects 20-50 years of age
boolean
C0001675 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Body Weight | Percentage Ideal Body Weight
Item
above 55kg and within ±20% ideal body weight
boolean
C0005910 (UMLS CUI [1])
C0439165 (UMLS CUI [2,1])
C0421272 (UMLS CUI [2,2])
Average Systolic Pressure | Average Diastolic blood pressure
Item
subjects who are in average of 130mmhg ≤ systolic blood pressure (sbp) < 160mmhg, 80mmhg ≤ diastolic blood pressure (dbp) < 100mmhg
boolean
C1510992 (UMLS CUI [1,1])
C0871470 (UMLS CUI [1,2])
C1510992 (UMLS CUI [2,1])
C0428883 (UMLS CUI [2,2])
Gender Pregnancy Absent | Gender Compliance Contraceptive methods
Item
female subject who confirmed non-pregnant status and agree to comply with proper contraception.
boolean
C0079399 (UMLS CUI [1,1])
C0032961 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C0079399 (UMLS CUI [2,1])
C1321605 (UMLS CUI [2,2])
C0700589 (UMLS CUI [2,3])
Informed Consent
Item
subjects who wrote informed consent
boolean
C0021430 (UMLS CUI [1])
Acute illness Suspected
Item
subjects who are suspected to have acute disease
boolean
C4061114 (UMLS CUI [1,1])
C0750491 (UMLS CUI [1,2])
Medical History Affecting Drug absorption | Medical History Affecting Drug distribution | Medical History Affecting Drug metabolism | Medical History Affecting Drug elimination
Item
subjects who have past history that may affect drug absorption, distribution, metabolism and elimination
boolean
C0262926 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0678745 (UMLS CUI [1,3])
C0262926 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C0699903 (UMLS CUI [2,3])
C0262926 (UMLS CUI [3,1])
C0392760 (UMLS CUI [3,2])
C0683140 (UMLS CUI [3,3])
C0262926 (UMLS CUI [4,1])
C0392760 (UMLS CUI [4,2])
C0683141 (UMLS CUI [4,3])
History of gastrointestinal disease
Item
subjects who have gastrointestinal history
boolean
C0455553 (UMLS CUI [1])
Heart rate
Item
subjects whose heartrate is less than 60
boolean
C0018810 (UMLS CUI [1])
Orthostatic Hypotension Suspected
Item
subject who suspected to orthostatic hypotension
boolean
C0020651 (UMLS CUI [1,1])
C0750491 (UMLS CUI [1,2])
Hypersensitivity Clinical Significance
Item
subjects who have clinically significant allergy disease
boolean
C0020517 (UMLS CUI [1,1])
C2826293 (UMLS CUI [1,2])
Study Subject Participation Status | Investigational New Drugs | Investigational Medical Device
Item
subject is currently participating or has participating in a study with an investigational compound or device within 30 days of signing informed consent
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
C2346570 (UMLS CUI [3])
Administration of medication Recent | Take non-prescription medications Recent
Item
administration of prescription drug within 14 days or over the counter (otc) drug within 7 days
boolean
C3469597 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
C3843194 (UMLS CUI [2,1])
C0332185 (UMLS CUI [2,2])
History of drug abuse | Drug screen positive
Item
subjects who have past history of drug abuse and positive in drug screening test
boolean
C1299544 (UMLS CUI [1])
C0743295 (UMLS CUI [2])
Blood donation Recent | Platelet donation Recent
Item
subjects who donate whole blood within 60 days and platelet within 30days.
boolean
C4316802 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
C0005821 (UMLS CUI [2,1])
C0680854 (UMLS CUI [2,2])
C0332185 (UMLS CUI [2,3])
ST. JOHN'S WORT EXTRACT | Cytochrome P-450 Enzyme Inhibitors | Cytochrome P450 Inducers
Item
subjects taking st john's wort or cyp inhibitor and inducer
boolean
C0813171 (UMLS CUI [1])
C3850070 (UMLS CUI [2])
C3500477 (UMLS CUI [3])