Age
Item
male or female 18-60 years of age
boolean
C0001779 (UMLS CUI [1])
Patient Appropriate Live donor renal transplant | Haplotype Identical Donor Identified
Item
candidate for a living-donor renal allograft with a one haplotype identical donor identified.
boolean
C0030705 (UMLS CUI [1,1])
C1548787 (UMLS CUI [1,2])
C0401177 (UMLS CUI [1,3])
C0018591 (UMLS CUI [2,1])
C0205280 (UMLS CUI [2,2])
C0040288 (UMLS CUI [2,3])
C0205396 (UMLS CUI [2,4])
Live donor renal transplant First | Live donor renal transplant second | Cadaveric renal transplant First
Item
first or second transplant with either a living donor or cadaveric transplant as the first transplant.
boolean
C0401177 (UMLS CUI [1,1])
C0205435 (UMLS CUI [1,2])
C0401177 (UMLS CUI [2,1])
C0205436 (UMLS CUI [2,2])
C0401176 (UMLS CUI [3,1])
C0205435 (UMLS CUI [3,2])
Epstein-Barr Virus Serologic test Positive
Item
positive serologic testing for ebv indicating past exposure.
boolean
C0014644 (UMLS CUI [1,1])
C0036743 (UMLS CUI [1,2])
C1514241 (UMLS CUI [1,3])
Exclusion Criteria Main
Item
key exclusion criteria:
boolean
C0680251 (UMLS CUI [1,1])
C1542147 (UMLS CUI [1,2])
ABO blood group Inconsistent Live donor renal transplant
Item
abo blood group-incompatible renal allograft.
boolean
C0200499 (UMLS CUI [1,1])
C0442809 (UMLS CUI [1,2])
C0401177 (UMLS CUI [1,3])
HLA antibody identification | Antihuman globulin | ELISA
Item
evidence of anti-hla antibody within 60 days prior to transplant as assessed by routine methodology (ahg and/or elisa)
boolean
C3508207 (UMLS CUI [1])
C1441481 (UMLS CUI [2])
C0014441 (UMLS CUI [3])
HIV Seropositivity | Hepatitis B core antigen positive | Hepatitis C virus test positive | Hepatitis B surface antigen positive
Item
positive testing for: hiv, hepatitis b core antigen, or hepatitis c virus or positivity for hepatitis b surface antigen.
boolean
C0019699 (UMLS CUI [1])
C0262507 (UMLS CUI [2])
C2748185 (UMLS CUI [3])
C0149709 (UMLS CUI [4])
Cardiac ejection fraction | Cardiac insufficiency
Item
cardiac ejection fraction < 40% or clinical evidence of insufficiency.
boolean
C0232174 (UMLS CUI [1])
C0018801 (UMLS CUI [2])
Malignant Neoplasms | Exception Basal cell carcinoma | Exception Carcinoma in situ of uterine cervix
Item
history of cancer other than basal cell carcinoma of the skin or carcinoma in situ of the cervix.
boolean
C0006826 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0851140 (UMLS CUI [3,2])
Kidney Disease | High risk of Disease recurrence Transplanted kidney | Primary Focal Segmental Glomerulosclerosis | Glomerulonephritis Type
Item
underlying renal disease etiology with a high risk of disease recurrence in the transplanted kidney (such as focal segmental glomerulosclerosis, type i or ii nonproliferative glomerulonephritis).
boolean
C0022658 (UMLS CUI [1])
C0332167 (UMLS CUI [2,1])
C0679254 (UMLS CUI [2,2])
C1261317 (UMLS CUI [2,3])
C1709661 (UMLS CUI [3])
C0017658 (UMLS CUI [4,1])
C0332307 (UMLS CUI [4,2])
Prior radiation therapy Dose Limiting
Item
prior dose-limiting radiation therapy.
boolean
C0279134 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0439801 (UMLS CUI [1,3])
Liver function tests abnormal | Alanine aminotransferase (ALT) level abnormal | AST/SGOT level abnormal | Alkaline phosphatase abnormal | Bilirubin abnormal | Coagulation test abnormal | Prothrombin time abnormal | Abnormal partial thromboplastin time (PTT)
Item
abnormal (>2 times lab normal) values for (a) liver function chemistries (alt, ast, ap), (b) bilirubin, (c) coagulation studies (pt, ptt).
boolean
C0151766 (UMLS CUI [1])
C0580469 (UMLS CUI [2])
C0580475 (UMLS CUI [3])
C0740888 (UMLS CUI [4])
C1142335 (UMLS CUI [5])
C1504379 (UMLS CUI [6])
C0580412 (UMLS CUI [7])
C4062448 (UMLS CUI [8])
Medical condition Study Subject Participation Status Inconsistent
Item
the presence of any medical condition that the investigator deems incompatible with participation in the trial.
boolean
C3843040 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C0442809 (UMLS CUI [1,3])