Age
Item
males and females, 18-35 years of age.
boolean
C0001779 (UMLS CUI [1])
South Asian | Caucasians
Item
south asian or caucasian descent through self-identification (south asians are to have both biological parents with ancestry from india, pakistan, sri lanka, nepal and bangladesh and no known non-south asian ancestry in parents; caucasians are to have both biological parents who self-identify as caucasian and no known non-caucasian ancestry in parents).
boolean
C1519427 (UMLS CUI [1])
C0043157 (UMLS CUI [2])
Body mass index | Obesity Absent
Item
body mass index (bmi) 18.0-24.9 kg/m2 with no history of obesity.
boolean
C1305855 (UMLS CUI [1])
C0028754 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Glucose measurement, fasting | 2-hour postprandial blood glucose measurement | Oral Glucose Tolerance Test
Item
fasting glucose <100 mg/dl, 2h glucose ogtt < 140 mg/dl.
boolean
C0202045 (UMLS CUI [1])
C2238058 (UMLS CUI [2])
C0029161 (UMLS CUI [3])
Triglycerides measurement | Serum HDL cholesterol measurement | Serum LDL cholesterol measurement
Item
tg <200 mg/dl, hdl cholesterol >30 mg/dl, ldl cholesterol <160 mg/dl.
boolean
C0202236 (UMLS CUI [1])
C0428472 (UMLS CUI [2])
C0428474 (UMLS CUI [3])
Fish Oil Discontinue Willing | Fish Oil Discontinue Able | Fiber Supplements Discontinue Willing | Fiber Supplements Discontinue Able | Vitamins Discontinue Willing | Vitamins Discontinue Able | Supplements Discontinue Willing | Supplements Discontinue Able
Item
willing and able to stop fish oil, fiber supplement, other non-prescribed vitamins/supplements for 1 week prior to visit #2 until completion of study.
boolean
C0016157 (UMLS CUI [1,1])
C1444662 (UMLS CUI [1,2])
C0600109 (UMLS CUI [1,3])
C0016157 (UMLS CUI [2,1])
C1444662 (UMLS CUI [2,2])
C0085732 (UMLS CUI [2,3])
C0012173 (UMLS CUI [3,1])
C0242295 (UMLS CUI [3,2])
C1444662 (UMLS CUI [3,3])
C0600109 (UMLS CUI [3,4])
C0012173 (UMLS CUI [4,1])
C0242295 (UMLS CUI [4,2])
C1444662 (UMLS CUI [4,3])
C0085732 (UMLS CUI [4,4])
C0042890 (UMLS CUI [5,1])
C1444662 (UMLS CUI [5,2])
C0600109 (UMLS CUI [5,3])
C0042890 (UMLS CUI [6,1])
C1444662 (UMLS CUI [6,2])
C0085732 (UMLS CUI [6,3])
C0242295 (UMLS CUI [7,1])
C1444662 (UMLS CUI [7,2])
C0600109 (UMLS CUI [7,3])
C0242295 (UMLS CUI [8,1])
C1444662 (UMLS CUI [8,2])
C0085732 (UMLS CUI [8,3])
Alcohol Abstinence Duration
Item
willing to not drink alcohol for 24-hours before visit #2.
boolean
C0678274 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
Informed Consent
Item
willing and able to provide informed consent.
boolean
C0021430 (UMLS CUI [1])
Diabetes Mellitus | Endocrine System Disease | Hepatitis | Liver disease | HIV Infection | Autoimmune Disease
Item
history of diabetes or other endocrine disorder, hepatitis or other liver disorder, hiv, or autoimmune disease.
boolean
C0011849 (UMLS CUI [1])
C0014130 (UMLS CUI [2])
C0019158 (UMLS CUI [3])
C0023895 (UMLS CUI [4])
C0019693 (UMLS CUI [5])
C0004364 (UMLS CUI [6])
Pharmaceutical Preparations Affecting Lipids | Contraceptives, Oral, Hormonal
Item
medication(s) known to affect lipids, including hormonal contraceptives.
boolean
C0013227 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0023779 (UMLS CUI [1,3])
C0009907 (UMLS CUI [2])
Illness Recent
Item
recent acute illness
boolean
C0221423 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Gastrointestinal Disease Resulting in Gastrointestinal dysfunction | Gastrointestinal Disease Resulting in Malabsorption
Item
gastrointestinal disease resulting in significant gi dysfunction or malabsorption.
boolean
C0017178 (UMLS CUI [1,1])
C0332294 (UMLS CUI [1,2])
C0679407 (UMLS CUI [1,3])
C0017178 (UMLS CUI [2,1])
C0332294 (UMLS CUI [2,2])
C3714745 (UMLS CUI [2,3])
Tobacco use
Item
cigarette smoking
boolean
C0543414 (UMLS CUI [1])
Alcohol abuse Drinks U/day | Illicit drug use
Item
history of ethanol abuse (current intake >2 drinks/day) or illicit drugs.
boolean
C0085762 (UMLS CUI [1,1])
C0001967 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
C0281875 (UMLS CUI [2])
Mental Disorders, Severe
Item
history of severe psychiatric illness
boolean
C4046029 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
if female, pregnant or breastfeeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Study Subject Participation Status | Investigational New Drugs
Item
participation in an investigational drug study within one month of screening.
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
Diet unusual | Physical activity Extreme
Item
unusual diet or extreme level of physical activity
boolean
C2163366 (UMLS CUI [1])
C0026606 (UMLS CUI [2,1])
C0205403 (UMLS CUI [2,2])
Condition Study Subject Participation Status Excluded
Item
have any other condition, which in the opinion of the investigator, should prohibit the participation in the study
boolean
C0348080 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C0332196 (UMLS CUI [1,3])