Postmenopausal state
Item
postmenopausal (no menstrual cycle in the past 12 months)
boolean
C0232970 (UMLS CUI [1])
Carcinoma Incident | Primary Carcinoma | Invasive Carcinoma | Ductal Carcinoma | Carcinoma, Lobular | Carcinoma TNM clinical staging | Oestrogen receptor positive breast cancer | Breast Carcinoma Estrogen receptor negative | DCIS
Item
diagnosed with incident, primary, invasive, ductal or lobular, or other epithelial malignancy, clinical stage i or ii, er positive or negative breast cancer, or ductal carcinoma in situ (dcis)
boolean
C0007097 (UMLS CUI [1,1])
C1551358 (UMLS CUI [1,2])
C1335475 (UMLS CUI [2])
C1334274 (UMLS CUI [3])
C1176475 (UMLS CUI [4])
C0206692 (UMLS CUI [5])
C0007097 (UMLS CUI [6,1])
C3258246 (UMLS CUI [6,2])
C2938924 (UMLS CUI [7])
C0678222 (UMLS CUI [8,1])
C0279756 (UMLS CUI [8,2])
C0007124 (UMLS CUI [9])
Neoadjuvant Hormone Therapy Absent | Neoadjuvant Chemotherapy Absent
Item
no neoadjuvant endocrine therapy or chemotherapy within 12 months
boolean
C0600558 (UMLS CUI [1,1])
C0279025 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C0600558 (UMLS CUI [2,1])
C3665472 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
ECOG performance status
Item
have an eastern cooperative oncology group (ecog) performance status of =< 2
boolean
C1520224 (UMLS CUI [1])
Avoidance Cruciferous vegetables
Item
willing to avoid cruciferous vegetable intake during the study period (2 weeks)
boolean
C0870186 (UMLS CUI [1,1])
C0453113 (UMLS CUI [1,2])
Able to swallow Oral medication | Ability Retain Oral medication
Item
demonstrate the ability to swallow and retain oral medication
boolean
C2712086 (UMLS CUI [1,1])
C0175795 (UMLS CUI [1,2])
C0085732 (UMLS CUI [2,1])
C0333118 (UMLS CUI [2,2])
C0175795 (UMLS CUI [2,3])
Comprehension Study Protocol | Comprehension Study Protocol Patient Representative | Informed Consent | Informed Consent Patient Representative
Item
subject or legal representative must understand the investigational nature of this study and sign an independent ethics committee/institutional review board approved written informed consent form prior to receiving any study related procedure
boolean
C0162340 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])
C0162340 (UMLS CUI [2,1])
C2348563 (UMLS CUI [2,2])
C0030701 (UMLS CUI [2,3])
C0021430 (UMLS CUI [3])
C0021430 (UMLS CUI [4,1])
C0030701 (UMLS CUI [4,2])
Invasive carcinoma of breast Previous | Mastectomy Previous | irradiation of breast Previous
Item
prior invasive breast cancer, prior mastectomy or breast radiation within 12 months
boolean
C0853879 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C0024881 (UMLS CUI [2,1])
C0205156 (UMLS CUI [2,2])
C2148528 (UMLS CUI [3,1])
C0205156 (UMLS CUI [3,2])
Hormone Therapy Reproductive | Tamoxifen | Aromatase Inhibitors | Estrogen Antagonists Affecting Biomarkers
Item
current or recent use of reproductive hormone therapy, tamoxifen, aromatase inhibitor or other estrogen inhibitors within the last 90 days, which may affect biomarkers
boolean
C0279025 (UMLS CUI [1,1])
C0035150 (UMLS CUI [1,2])
C0039286 (UMLS CUI [2])
C0593802 (UMLS CUI [3])
C0014930 (UMLS CUI [4,1])
C0392760 (UMLS CUI [4,2])
C0005516 (UMLS CUI [4,3])
Intolerance to Broccoli | Intolerance to ITC-BSE
Item
intolerance to broccoli/itc-bse taste
boolean
C1744706 (UMLS CUI [1,1])
C0330498 (UMLS CUI [1,2])
C1744706 (UMLS CUI [2,1])
C0124209 (UMLS CUI [2,2])
C1707048 (UMLS CUI [2,3])
Broccoli sprout extract Interferes with Research results
Item
current ingestion of broccoli sprout extract, which may confound study results
boolean
C1707048 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0683954 (UMLS CUI [1,3])
Cancer treatment Affecting Biomarkers
Item
current or recent treatment for any malignancy within the last one year, which may affect biomarkers
boolean
C0920425 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0005516 (UMLS CUI [1,3])
Crohn Disease | Celiac Disease | Malabsorption Syndrome Interferes with Broccoli sprout extract Digestion | Malabsorption Syndrome Interferes with Broccoli sprout extract Absorption
Item
history of crohn's disease, celiac sprue or other malabsorption syndrome which may interfere with digestion and absorption of broccoli sprout extract
boolean
C0010346 (UMLS CUI [1])
C0007570 (UMLS CUI [2])
C0024523 (UMLS CUI [3,1])
C0521102 (UMLS CUI [3,2])
C1707048 (UMLS CUI [3,3])
C0012238 (UMLS CUI [3,4])
C0024523 (UMLS CUI [4,1])
C0521102 (UMLS CUI [4,2])
C1707048 (UMLS CUI [4,3])
C0237442 (UMLS CUI [4,4])