Age
Item
age range: 18-65 years old
boolean
C0001779 (UMLS CUI [1])
Diffuse Large B-Cell Lymphoma
Item
histological confirmed diffuse large b-cell lymphoma
boolean
C0079744 (UMLS CUI [1])
Refractory Disease | First Relapse
Item
refractory or first relapsed disease
boolean
C1514815 (UMLS CUI [1])
C4054953 (UMLS CUI [2])
Exposure to Anthracyclines
Item
prior anthracycline exposure
boolean
C0332157 (UMLS CUI [1,1])
C0282564 (UMLS CUI [1,2])
Measurable Disease
Item
measurable disease
boolean
C1513041 (UMLS CUI [1])
ECOG performance status
Item
ecog performance status 0-1
boolean
C1520224 (UMLS CUI [1])
Life Expectancy
Item
life expectancy of more than 3 months
boolean
C0023671 (UMLS CUI [1])
Bone Marrow function | Absolute neutrophil count | Platelet Count measurement | Hemoglobin measurement
Item
bone marrow function: anc≧1.5×109/l, plt≧100×109/l, hb≧90g/l
boolean
C0005953 (UMLS CUI [1,1])
C0031843 (UMLS CUI [1,2])
C0948762 (UMLS CUI [2])
C0032181 (UMLS CUI [3])
C0518015 (UMLS CUI [4])
Liver function | Serum total bilirubin measurement | Alanine aminotransferase measurement | Aspartate aminotransferase measurement
Item
liver function: total bilirubin, alt and ast <1.5×unl
boolean
C0232741 (UMLS CUI [1])
C1278039 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
C0201899 (UMLS CUI [4])
Renal function | Creatinine measurement, serum | Creatinine clearance measurement
Item
renal function: cr<1.5×unl, ccr≧50ml/min
boolean
C0232804 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
C0373595 (UMLS CUI [3])
Medical contraindication Absent Transplantation
Item
no contraindication for transplantation
boolean
C1301624 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0040732 (UMLS CUI [1,3])
Central Nervous System Involvement | Bone Marrow Involvement
Item
evidence of cns and bone marrow involvement
boolean
C4050309 (UMLS CUI [1])
C1517677 (UMLS CUI [2])
Chemotherapy Type Quantity
Item
more than 1 type of chemotherapy regimens exposure
boolean
C0392920 (UMLS CUI [1,1])
C0332307 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
HBV DNA increased
Item
high level of hbv dna
boolean
C1262159 (UMLS CUI [1])
Medical contraindication Methylprednisolone High dose
Item
contraindication of high-dose methylprednisolone
boolean
C1301624 (UMLS CUI [1,1])
C0025815 (UMLS CUI [1,2])
C0444956 (UMLS CUI [1,3])
Pregnancy | Breast Feeding
Item
pregnant or lactating women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Cancer Other | Exception Basal cell carcinoma Cured | Exception Carcinoma in situ of uterine cervix Cured
Item
history of other malignancies except cured basal cell carcinoma of skin and carcinoma in-situ of uterine cervix
boolean
C1707251 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1880198 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0851140 (UMLS CUI [3,2])
C1880198 (UMLS CUI [3,3])
Allergic Reaction Rituximab | Hypersensitivity Rituximab
Item
history of allergic reaction/hypersensitivity to rituximab
boolean
C1527304 (UMLS CUI [1,1])
C0393022 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0393022 (UMLS CUI [2,2])
Communicable Disease
Item
significant active infection
boolean
C0009450 (UMLS CUI [1])