Breast Diffuse Large B-Cell Lymphoma Untreated
Item
previously untreated patients with dlbcl of the breast.
boolean
C1511306 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
Neoplasm CD20 antigen positive
Item
patients must have cd20 positive tumors.
boolean
C0027651 (UMLS CUI [1,1])
C3888518 (UMLS CUI [1,2])
TNM clinical staging
Item
stage ie or iie.
boolean
C3258246 (UMLS CUI [1])
Measurable Disease Quantity | Evaluable Disease Quantity | Baseline Measurement | Baseline Evaluation
Item
must have at least one objective measurable or evaluable disease. baseline measurements and evaluations must be obtained within 4 weeks of registration to the study.
boolean
C1513041 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C1516986 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C1442488 (UMLS CUI [3,1])
C0242485 (UMLS CUI [3,2])
C1442488 (UMLS CUI [4,1])
C1261322 (UMLS CUI [4,2])
ECOG performance status
Item
patients must have an ecog performance status 0-2.
boolean
C1520224 (UMLS CUI [1])
Organ function Laboratory Procedures
Item
patients must have adequate organ function as evidenced by the following laboratory studies ( within 2 weeks prior to registration):
boolean
C0678852 (UMLS CUI [1,1])
C0022885 (UMLS CUI [1,2])
Creatinine clearance measurement
Item
creatinine clearance > 50 ml/min
boolean
C0373595 (UMLS CUI [1])
Serum total bilirubin measurement | Aspartate aminotransferase measurement | Hepatic Involvement Lymphoma
Item
total bilirubin < 2.0 mg/dl and ast < 2 x upper limit of normal. if documented hepatic involvement with lymphoma, total bilirubin can be < 3 x uln, and ast < 5 x uln.
boolean
C1278039 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C0441932 (UMLS CUI [3,1])
C0024299 (UMLS CUI [3,2])
Absolute neutrophil count | Platelet Count measurement | Bone Marrow Involvement Lymphoma
Item
absolute neutrophil count > 1500/mm3 and platelet count > 100,000/mm3. if documented bone marrow involvement with lymphoma, absolute neutrophil count > 500/mm3 and platelet count > 50,000/mm3.
boolean
C0948762 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C1517677 (UMLS CUI [3,1])
C0024299 (UMLS CUI [3,2])
Age
Item
patients must be age > 18 years.
boolean
C0001779 (UMLS CUI [1])
Left ventricular ejection fraction Normal
Item
patients must have a normal left ventricular ejection fraction to be eligible.
boolean
C0428772 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
CNS metastases | CNS metastases Radiography | Prior Therapy Lesion of brain | Lesion of brain Resected | Lesion of brain Asymptomatic | Involvement Leptomeningeal
Item
historical or radiographic evidence of cns metastasis including previously treated, resected or asymptomatic brain lesions or leptomeningeal involvement.
boolean
C0686377 (UMLS CUI [1])
C0686377 (UMLS CUI [2,1])
C0034571 (UMLS CUI [2,2])
C1514463 (UMLS CUI [3,1])
C0221505 (UMLS CUI [3,2])
C0221505 (UMLS CUI [4,1])
C1521996 (UMLS CUI [4,2])
C0221505 (UMLS CUI [5,1])
C0231221 (UMLS CUI [5,2])
C1314939 (UMLS CUI [6,1])
C0521401 (UMLS CUI [6,2])
Pregnancy | Breast Feeding | Childbearing Potential Contraceptive methods | Gender Sexually active Contraceptive methods
Item
pregnant or breast feeding patients. women of childbearing potential and sexually active males are strongly advised to use an accepted and effective method of contraception.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C0079399 (UMLS CUI [4,1])
C0241028 (UMLS CUI [4,2])
C0700589 (UMLS CUI [4,3])
Communicable Disease Requirement Antibiotics Parenteral
Item
active infection requiring parental antibiotics.
boolean
C0009450 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0003232 (UMLS CUI [1,3])
C1518896 (UMLS CUI [1,4])
HIV Infection
Item
known hiv infection
boolean
C0019693 (UMLS CUI [1])