All
Item
all:
boolean
C0444868 (UMLS CUI [1])
Age
Item
males or females aged >/- 50 years
boolean
C0001779 (UMLS CUI [1])
Comprehension Study Protocol | Informed Consent
Item
participants must be able to understand the information provided on purpose and conduct of the clinical study, must be capable of giving fully informed consent in writing, and have read and signed the informed consent prior to study participation
boolean
C0162340 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])
C0021430 (UMLS CUI [2])
Healthy Volunteers Imaging of brain
Item
healthy volunteers for brain imaging:
boolean
C1708335 (UMLS CUI [1,1])
C0203860 (UMLS CUI [1,2])
Mini-mental status exam score (___/30)
Item
mini-mental state examination (mmse) score of >/= 28
boolean
C2225229 (UMLS CUI [1])
Clinical dementia rating scale
Item
cdr score of zero (0)
boolean
C0451074 (UMLS CUI [1])
Patients Imaging of brain
Item
patients for brain imaging:
boolean
C0030705 (UMLS CUI [1,1])
C0203860 (UMLS CUI [1,2])
Alzheimer's Disease Probable | Impaired cognition | Memory impairment | Aphasia | Apraxia | Agnosia | Executive dysfunction
Item
patient fulfills diagnostic and statistical manual of mental disorders (dsm-iv) and national institute of neurological and communicative disorders and stroke, alzheimer's disease and related disorders association (nincds-adrda) criteria for probable alzheimer's disease (ad), which are cognitive deficits such as memory decline and impairment in at least one other cognitive domain (e.g. aphasia, apraxia, agnosia or executive dysfunction)
boolean
C0002395 (UMLS CUI [1,1])
C0033204 (UMLS CUI [1,2])
C0338656 (UMLS CUI [2])
C0233794 (UMLS CUI [3])
C0003537 (UMLS CUI [4])
C0003635 (UMLS CUI [5])
C0001816 (UMLS CUI [6])
C2748208 (UMLS CUI [7])
Mild dementia Mini-mental status exam score (___/30) | Moderate dementia Mini-mental status exam score (___/30) | Mild dementia Clinical dementia rating scale | Moderate dementia Clinical dementia rating scale
Item
patient has mild to moderate dementia with a dementia score of >/= 20 on the mini mental state examination (mmse) / with a clinical dementia rating score of 1 or 2 (cdr)
boolean
C3494623 (UMLS CUI [1,1])
C2225229 (UMLS CUI [1,2])
C3494871 (UMLS CUI [2,1])
C2225229 (UMLS CUI [2,2])
C3494623 (UMLS CUI [3,1])
C0451074 (UMLS CUI [3,2])
C3494871 (UMLS CUI [4,1])
C0451074 (UMLS CUI [4,2])
All
Item
all:
boolean
C0444868 (UMLS CUI [1])
Disease Significant Absent | Drug use Absent
Item
no significant disease or drug use
boolean
C0012634 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C0242510 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Patients Imaging of brain
Item
patients for brain imaging:
boolean
C0030705 (UMLS CUI [1,1])
C0203860 (UMLS CUI [1,2])
Nervous system disorder Other | Mental disorder Other
Item
evidence for any other neurological or psychiatric disease
boolean
C0027765 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0004936 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
Healthy Volunteers Imaging of brain
Item
healthy volunteers for brain imaging:
boolean
C1708335 (UMLS CUI [1,1])
C0203860 (UMLS CUI [1,2])
Family history of Alzheimer's disease | First Degree Relative | Second Degree Relative | Age
Item
family history of alzheimer's disease in a 1st or 2nd degree relative under 75 years of age
boolean
C1271045 (UMLS CUI [1])
C1517194 (UMLS CUI [2])
C1519210 (UMLS CUI [3])
C0001779 (UMLS CUI [4])