Gender | Diabetes Mellitus, Non-Insulin-Dependent | Hemoglobin A1c measurement | Insulin regime With intensity | Insulin injection Daily Dose Multiple | Continuous subcutaneous infusion of insulin | Humulin insulin | Insulin U/day Quantity | Other Coding
Item
1. male and female patients with type 2 diabetes with hba1c from 6.5 to 10% treated with intensive insulin therapy (mdi or csii, including u-500 insulin-treated patients) using > 100 units of insulin, with or without a stable dose of oral insulin sensitizing medications, for at least three months.
boolean
C0079399 (UMLS CUI [1])
C0011860 (UMLS CUI [2])
C0474680 (UMLS CUI [3])
C0557978 (UMLS CUI [4,1])
C0522510 (UMLS CUI [4,2])
C0199782 (UMLS CUI [5,1])
C2348070 (UMLS CUI [5,2])
C0439064 (UMLS CUI [5,3])
C0393124 (UMLS CUI [6])
C0020171 (UMLS CUI [7])
C0021641 (UMLS CUI [8,1])
C0456683 (UMLS CUI [8,2])
C1265611 (UMLS CUI [8,3])
C3846158 (UMLS CUI [9])
Age
Item
2. aged 18 to 80 years.
boolean
C0001779 (UMLS CUI [1])
Childbearing Potential Contraceptive methods
Item
3. females of child-bearing potential must be using adequate form of contraception.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Blood Glucose Self-Monitoring times/day | Continuous glucose monitoring | Protocol Compliance
Item
4. patient willing to monitor bg four times daily, use cgm, and comply with study-related protocol.
boolean
C0005803 (UMLS CUI [1,1])
C0439511 (UMLS CUI [1,2])
C4523945 (UMLS CUI [2])
C0525058 (UMLS CUI [3])
Diabetes Mellitus, Insulin-Dependent
Item
1. type 1 diabetes.
boolean
C0011854 (UMLS CUI [1])
GLP-1 Receptor Agonist
Item
2. use of any glp-1 receptor agonist within previous three months.
boolean
C2917359 (UMLS CUI [1])
Dipeptidyl Peptidase 4 Inhibitors | Pills Releasing Insulin
Item
3. use of dpp-4 inhibitors or oral insulin secretagogues within the previous three months.
boolean
C2917254 (UMLS CUI [1])
C0994475 (UMLS CUI [2,1])
C1283071 (UMLS CUI [2,2])
C0021641 (UMLS CUI [2,3])
Glucocorticoids | Exception Glucocorticoids by Inhalation
Item
4. use of glucocorticoids (except inhaled).
boolean
C0017710 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0017710 (UMLS CUI [2,2])
C0205535 (UMLS CUI [2,3])
Investigational New Drugs
Item
5. use of any experimental drug within previous three months.
boolean
C0013230 (UMLS CUI [1])
Hypersensitivity Liraglutide | Hypersensitivity NovoLog | Hypersensitivity Levemir | Hypersensitivity Suspected Liraglutide | Hypersensitivity Suspected NovoLog | Hypersensitivity Suspected Levemir
Item
6. known or suspected allergy to liraglutide, novolog or levemir.
boolean
C0020517 (UMLS CUI [1,1])
C1456408 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0939412 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C1314782 (UMLS CUI [3,2])
C0020517 (UMLS CUI [4,1])
C0750491 (UMLS CUI [4,2])
C1456408 (UMLS CUI [4,3])
C0020517 (UMLS CUI [5,1])
C0750491 (UMLS CUI [5,2])
C0939412 (UMLS CUI [5,3])
C0020517 (UMLS CUI [6,1])
C0750491 (UMLS CUI [6,2])
C1314782 (UMLS CUI [6,3])
Medullary carcinoma of thyroid | Familial medullary thyroid carcinoma | Multiple Endocrine Neoplasia Type | Family history of multiple endocrine neoplasia Type
Item
7. personal or family history of medullary carcinoma of the thyroid or men-2.
boolean
C0238462 (UMLS CUI [1])
C1833921 (UMLS CUI [2])
C0027662 (UMLS CUI [3,1])
C0332307 (UMLS CUI [3,2])
C4039247 (UMLS CUI [4,1])
C0332307 (UMLS CUI [4,2])
Chronic Kidney Disease | Creatinine measurement, serum
Item
8. concomitant chronic renal disease with creatinine > 1.5%.
boolean
C1561643 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
Chronic liver disease | Gastrointestinal Disease chronic | Chronic disease | Pancreatitis | Cardiovascular Disease | Exception Exercise-induced angina Stable
Item
9. concomitant chronic hepatic, gastrointestinal or other illness (including pancreatitis or active cardiovascular disease except stable exertional angina).
boolean
C0341439 (UMLS CUI [1])
C0017178 (UMLS CUI [2,1])
C0205191 (UMLS CUI [2,2])
C0008679 (UMLS CUI [3])
C0030305 (UMLS CUI [4])
C0007222 (UMLS CUI [5])
C1705847 (UMLS CUI [6,1])
C0577698 (UMLS CUI [6,2])
C0205360 (UMLS CUI [6,3])
Blood Glucose Self-Monitoring Unable | Continuous glucose monitoring Unable | Protocol Compliance Unable | Blood Glucose Self-Monitoring Unwilling | Continuous glucose monitoring Unwilling | Protocol Compliance Unwilling
Item
10. inability or unwillingness to monitor bg, use cgm, or comply with study protocol.
boolean
C0005803 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
C4523945 (UMLS CUI [2,1])
C1299582 (UMLS CUI [2,2])
C0525058 (UMLS CUI [3,1])
C1299582 (UMLS CUI [3,2])
C0005803 (UMLS CUI [4,1])
C0558080 (UMLS CUI [4,2])
C4523945 (UMLS CUI [5,1])
C0558080 (UMLS CUI [5,2])
C0525058 (UMLS CUI [6,1])
C0558080 (UMLS CUI [6,2])
Childbearing Potential Contraceptive methods Unwilling | Pregnancy intended | Breast Feeding
Item
11. women of child-bearing potential unwilling to use adequate contraception, intending to become pregnant or breast-feeding.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0558080 (UMLS CUI [1,3])
C0032961 (UMLS CUI [2,1])
C1283828 (UMLS CUI [2,2])
C0006147 (UMLS CUI [3])