Diabetes Mellitus, Non-Insulin-Dependent
Item
men and women with type 2 diabetes mellitus
boolean
C0011860 (UMLS CUI [1])
Age | Cardiovascular Disease | Cardiovascular Disease Evidence Subclinical
Item
age above or equal to 50 years at screening and clinical evidence of cardiovascular disease or age above or equal to 60 years at screening and subclinical evidence of cardiovascular disease
boolean
C0001779 (UMLS CUI [1])
C0007222 (UMLS CUI [2])
C0007222 (UMLS CUI [3,1])
C3887511 (UMLS CUI [3,2])
C0205211 (UMLS CUI [3,3])
Antidiabetics Absent | Antidiabetics Oral Quantity | NPH insulin | Insulin Analog Active Long-term | Premixed insulin | Combined Modality Therapy
Item
anti-diabetic drug naïve, or treated with one or two oral antidiabetic drug (oads), or treated with human neutral protamin hagedorn (nph) insulin or long-acting insulin analogue or pre-mixed insulin, both types of insulin either alone or in combination with one or two oads
boolean
C0935929 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0935929 (UMLS CUI [2,1])
C1527415 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0021658 (UMLS CUI [3])
C2825028 (UMLS CUI [4,1])
C0205177 (UMLS CUI [4,2])
C0443252 (UMLS CUI [4,3])
C2069057 (UMLS CUI [5])
C0009429 (UMLS CUI [6])
Hemoglobin A1c measurement
Item
hba1c above or equal to 7.0% at screening
boolean
C0474680 (UMLS CUI [1])
Diabetes Mellitus, Insulin-Dependent
Item
type 1 diabetes mellitus
boolean
C0011854 (UMLS CUI [1])
GLP-1 Receptor Agonist | exenatide | liraglutide | Pramlintide
Item
use of glucagon-like peptide-1 (glp-1) receptor agonist (exenatide, liraglutide, or other) or pramlintide within 90 days prior to screening
boolean
C2917359 (UMLS CUI [1])
C0167117 (UMLS CUI [2])
C1456408 (UMLS CUI [3])
C0537551 (UMLS CUI [4])
Dipeptidyl Peptidase 4 Inhibitor
Item
use of any dipeptidyl peptidase 4 (dpp-iv) inhibitor within 30 days prior to screening
boolean
C3537161 (UMLS CUI [1])
Insulin regime | Exception Basal insulin | Exception Premixed insulin | Exception Insulin use short-term | Relationship Comorbidity
Item
treatment with insulin other than basal and pre-mixed insulin within 90 days prior to screening - except for short-term use in connection with intercurrent illness
boolean
C0557978 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0650607 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C2069057 (UMLS CUI [3,2])
C1705847 (UMLS CUI [4,1])
C0240016 (UMLS CUI [4,2])
C0443303 (UMLS CUI [4,3])
C0439849 (UMLS CUI [5,1])
C0009488 (UMLS CUI [5,2])
Poor glycemic control | Requirement Intensification therapy Immediate | Prevention Complications of Diabetes Mellitus | Prevention Diabetic Ketoacidosis
Item
acute decompensation of glycaemic control requiring immediate intensification of treatment to prevent acute complications of diabetes (eg diabetes ketoacidosis) within 90 days prior to screening
boolean
C0342299 (UMLS CUI [1])
C1514873 (UMLS CUI [2,1])
C1511484 (UMLS CUI [2,2])
C0205253 (UMLS CUI [2,3])
C2700409 (UMLS CUI [3,1])
C0342257 (UMLS CUI [3,2])
C2700409 (UMLS CUI [4,1])
C0011880 (UMLS CUI [4,2])
Pancreatitis, Chronic | Idiopathic acute pancreatitis
Item
history of chronic pancreatitis or idiopathic acute pancreatitis
boolean
C0149521 (UMLS CUI [1])
C0341461 (UMLS CUI [2])
Acute Coronary Syndrome | Cerebrovascular accident
Item
acute coronary or cerebro-vascular event within 90 days prior to randomisation
boolean
C0948089 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
Coronary revascularisation Planned | Carotid revascularisation Planned | Peripheral revascularisation Planned
Item
currently planned coronary, carotid or peripheral artery revascularisation
boolean
C0877341 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
C3495793 (UMLS CUI [2,1])
C1301732 (UMLS CUI [2,2])
C1096418 (UMLS CUI [3,1])
C1301732 (UMLS CUI [3,2])
Chronic heart failure New York Heart Association Classification
Item
chronic heart failure new york heart association (nyha) class iv
boolean
C0264716 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Multiple Endocrine Neoplasia Type | Family history of multiple endocrine neoplasia Type | Familial medullary thyroid carcinoma
Item
personal or family history of multiple endocrine neoplasia type 2 (men2) or familial medullary thyroid carcinoma
boolean
C0027662 (UMLS CUI [1,1])
C0332307 (UMLS CUI [1,2])
C4039247 (UMLS CUI [2,1])
C0332307 (UMLS CUI [2,2])
C1833921 (UMLS CUI [3])
Medullary carcinoma of thyroid
Item
personal history of non-familial medullary thyroid carcinoma
boolean
C0238462 (UMLS CUI [1])
Calcitonin measurement
Item
screening calcitonin above or equal to 50 ng/l
boolean
C0201924 (UMLS CUI [1])