Diabetes Mellitus, Non-Insulin-Dependent | Antidiabetics Oral Type Quantity | Traditional Chinese Medicine Relationship Antidiabetics Oral
Item
type 2 diabetes treated with a maximum of three different types of oral anti-diabetic drugs (oads) (including traditional chinese medicine which contains active ingredients of known oads) for more than 6 months
boolean
C0011860 (UMLS CUI [1])
C0935929 (UMLS CUI [2,1])
C1527415 (UMLS CUI [2,2])
C0332307 (UMLS CUI [2,3])
C1265611 (UMLS CUI [2,4])
C4331423 (UMLS CUI [3,1])
C0439849 (UMLS CUI [3,2])
C0935929 (UMLS CUI [3,3])
C1527415 (UMLS CUI [3,4])
Metformin Cumulative Dose U/day unchanged | Patients Chinese | Patients Japanese
Item
unchanged total daily dose of at least 1500 mg (chinese patients) or 500 mg (japanese patients) metformin for the last two months
boolean
C0025598 (UMLS CUI [1,1])
C2986497 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
C0442739 (UMLS CUI [1,4])
C0030705 (UMLS CUI [2,1])
C0152035 (UMLS CUI [2,2])
C0030705 (UMLS CUI [3,1])
C1556094 (UMLS CUI [3,2])
Cumulative Dose Daily unchanged | Pills Releasing Insulin | Cumulative Dose Daily Maximum Half
Item
unchanged total daily dose of at least half maximum recommended total daily dose of any insulin secretagogue for the last two months
boolean
C2986497 (UMLS CUI [1,1])
C0332173 (UMLS CUI [1,2])
C0442739 (UMLS CUI [1,3])
C0994475 (UMLS CUI [2,1])
C1283071 (UMLS CUI [2,2])
C0021641 (UMLS CUI [2,3])
C2986497 (UMLS CUI [3,1])
C0332173 (UMLS CUI [3,2])
C0806909 (UMLS CUI [3,3])
C2825407 (UMLS CUI [3,4])
Insulin Absent
Item
insulin naive
boolean
C0021641 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Hemoglobin A1c measurement
Item
hba1c between 7.0% and 10.0%
boolean
C0474680 (UMLS CUI [1])
Plasma fasting glucose measurement
Item
fpg (fasting plasma glucose) equal to or above 6.1 mmol/l (110mg/dl)
boolean
C0583513 (UMLS CUI [1])
Body mass index
Item
body mass index (bmi) below 40.0 kg/m^2
boolean
C1305855 (UMLS CUI [1])
Thiazolidinediones | Glucagon-like Peptide-1 (GLP-1) Antagonists
Item
treatment with any thiazolidinedione (tzd) and glp-1 (glucagon like peptide-1) receptor antagonists during the last 3 months before visit 1 in this trial
boolean
C1257987 (UMLS CUI [1])
C2916826 (UMLS CUI [2])
Disease Interferes with Clinical Trial | Condition Interferes with Clinical Trial
Item
any disease or condition which the investigator feels would interfere with the trial
boolean
C0012634 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0008976 (UMLS CUI [1,3])
C0348080 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0008976 (UMLS CUI [2,3])
Medical contraindication Metformin | Medical contraindication Glimepiride
Item
any contraindication to metformin or glimepiride (according to local labelling)
boolean
C1301624 (UMLS CUI [1,1])
C0025598 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0061323 (UMLS CUI [2,2])