Age
Item
subjects aged 40-75 years
boolean
C0001779 (UMLS CUI [1])
Enrollment Clinical Trial Specified
Item
subjects enrolled in the existing 'maastricht study' (m-study)
boolean
C1516879 (UMLS CUI [1,1])
C0008976 (UMLS CUI [1,2])
C0205369 (UMLS CUI [1,3])
Written consent Research Additional
Item
subjects gave written consent to be approached for additional research
boolean
C0811746 (UMLS CUI [1,1])
C0035168 (UMLS CUI [1,2])
C1524062 (UMLS CUI [1,3])
Performance Percentage | Cognitive functions Testing | Stroop Test | Modified word learning test
Item
subjects belongs to the 20% of the worst and 20% of the best performing (as based on neuropsychological cognitive testing (stroop color-word test, 15 word learning test, and delayed recall and recognition 15 word learning test)
boolean
C1882330 (UMLS CUI [1,1])
C0439165 (UMLS CUI [1,2])
C0392335 (UMLS CUI [2,1])
C0039593 (UMLS CUI [2,2])
C2718024 (UMLS CUI [3])
C0451314 (UMLS CUI [4])
Individuals Non-Insulin-Dependent Diabetes Mellitus
Item
individuals diabetes type 2:
boolean
C0027361 (UMLS CUI [1,1])
C0011860 (UMLS CUI [1,2])
Fasting blood glucose measurement | Status post Blood glucose measurement Oral Glucose Tolerance Test | Oral hypoglycemic | Insulin use
Item
fasting blood glucose ≥ 7.0 mmol/l, after an oral glucose tolerance test (ogtt)blood glucose ≥ 11.1 mmol/l or used oral glucose-lowering medication or insulin
boolean
C0428568 (UMLS CUI [1])
C0231290 (UMLS CUI [2,1])
C0392201 (UMLS CUI [2,2])
C0029161 (UMLS CUI [2,3])
C0359086 (UMLS CUI [3])
C0240016 (UMLS CUI [4])
Metabolic Syndrome
Item
metabolic syndrome:
boolean
C0524620 (UMLS CUI [1])
Criteria Quantity Fulfill
Item
participants should meet three out of 5 of the following criteria [8]:
boolean
C0243161 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C1550543 (UMLS CUI [1,3])
Waist Circumference | Gender
Item
1. waist circumference > 88 cm (women), > 102 cm (men)
boolean
C0455829 (UMLS CUI [1])
C0079399 (UMLS CUI [2])
Triglycerides measurement
Item
2. triglycerides ≥ 1.7 mmol/l
boolean
C0202236 (UMLS CUI [1])
Serum HDL cholesterol measurement | Gender
Item
3. hdl cholesterol < 1.3 mmol/l (women), < 1.0 mmol/l (men)
boolean
C0428472 (UMLS CUI [1])
C0079399 (UMLS CUI [2])
Blood pressure determination
Item
4. blood pressure ≥ 130/85 mmhg (or medication)
boolean
C0005824 (UMLS CUI [1])
Fasting blood glucose measurement | Status post Blood glucose measurement Oral Glucose Tolerance Test
Item
5. fasting blood glucose ≥ 6.1 mmol/l, after an ogtt blood glucose ≥ 7.8 mmol/l
boolean
C0428568 (UMLS CUI [1])
C0231290 (UMLS CUI [2,1])
C0392201 (UMLS CUI [2,2])
C0029161 (UMLS CUI [2,3])
Control Group
Item
control participants:
boolean
C0009932 (UMLS CUI [1])
Criteria Quantity Fulfill | Metabolic Syndrome | Non-Insulin-Dependent Diabetes Mellitus Absent
Item
those who fulfilled no more than 1 criterium of the metabolic syndrome, no dm2.
boolean
C0243161 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C1550543 (UMLS CUI [1,3])
C0524620 (UMLS CUI [2])
C0011860 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
Medical contraindication MRI | Artificial cardiac pacemaker | Neurostimulator | Pharmaceutical Preparation pump | Cochlear Implants | Hearing Implants | Tattoos | Foreign Bodies Metallic | Splinter Metallic Eye | Pregnancy | Claustrophobia | Vascular clamp Brain | Denture Containing Magnet
Item
contra-indications for mri examination (e.g. pacemaker; neurostimulator; medication pump; cochlear or hearing implant; tattoos or other items that cannot be removed and include metal parts (for instance from operations in the past); metal splinter in the eye; pregnancy and claustrophobia; brain vessel clamps; denture, which contains magnets).
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0030163 (UMLS CUI [2])
C0582124 (UMLS CUI [3])
C0013227 (UMLS CUI [4,1])
C0182537 (UMLS CUI [4,2])
C0009199 (UMLS CUI [5])
C0018767 (UMLS CUI [6,1])
C0021102 (UMLS CUI [6,2])
C1366940 (UMLS CUI [7])
C0016542 (UMLS CUI [8,1])
C2986473 (UMLS CUI [8,2])
C1960195 (UMLS CUI [9,1])
C2986473 (UMLS CUI [9,2])
C0015392 (UMLS CUI [9,3])
C0032961 (UMLS CUI [10])
C0008909 (UMLS CUI [11])
C0179955 (UMLS CUI [12,1])
C0006104 (UMLS CUI [12,2])
C0011394 (UMLS CUI [13,1])
C0332256 (UMLS CUI [13,2])
C0024483 (UMLS CUI [13,3])
Comorbidity Psychiatric | MRI Tests Functional Unable
Item
psychiatric co-morbidity and inability to perform the functional mri tests.
boolean
C0009488 (UMLS CUI [1,1])
C0205487 (UMLS CUI [1,2])
C0024485 (UMLS CUI [2,1])
C0022885 (UMLS CUI [2,2])
C0205245 (UMLS CUI [2,3])
C1299582 (UMLS CUI [2,4])
Cognitive Assessment Incomplete
Item
incomplete cognitive assessment data
boolean
C0870300 (UMLS CUI [1,1])
C0205257 (UMLS CUI [1,2])
Diabetes Mellitus, Insulin-Dependent
Item
diabetes mellitus type 1 (dm1)
boolean
C0011854 (UMLS CUI [1])
Performance Percentage | Cognitive functions Testing | Stroop Test | Modified word learning test
Item
subjects who are not belonging to the 20% of the worst and 20% of the best performing individuals (as based on neuropsychological cognitive testing (stroop color-word test, 15 word learning test, and delayed recall and recognition 15 word learning test).
boolean
C1882330 (UMLS CUI [1,1])
C0439165 (UMLS CUI [1,2])
C0392335 (UMLS CUI [2,1])
C0039593 (UMLS CUI [2,2])
C2718024 (UMLS CUI [3])
C0451314 (UMLS CUI [4])
Timepoint Visit Clinical Trial Specified
Item
last visit of the subjects to the m-study should be less than one year
boolean
C2348792 (UMLS CUI [1,1])
C0008952 (UMLS CUI [1,2])
C0008976 (UMLS CUI [1,3])
C0205369 (UMLS CUI [1,4])