Adult | Age
Item
adult patients, 40 to 70 years of age (inclusive) at screening
boolean
C0001675 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Non-Insulin-Dependent Diabetes Mellitus Disease length | Pharmaceutical Preparations Absent | Metformin Stable
Item
patients with type 2 diabetes mellitus diagnosed at least 12 weeks before screening and either drug-naïve or treated with stable metformin monotherapy for at least 12 weeks prior to screening
boolean
C0011860 (UMLS CUI [1,1])
C0872146 (UMLS CUI [1,2])
C0013227 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0025598 (UMLS CUI [3,1])
C0205360 (UMLS CUI [3,2])
Hemoglobin A1c measurement
Item
hba1c >/= 7 % and </= 9% at screening
boolean
C0474680 (UMLS CUI [1])
Coronary Artery Disease Absent
Item
absence of history of coronary artery disease
boolean
C1956346 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Diabetes Mellitus, Insulin-Dependent | Diabetes Mellitus Due to Injury of pancreas | Secondary diabetes mellitus
Item
diagnosis or history of type 1 diabetes mellitus, diabetes resulting from pancreatic injury, or secondary forms of diabetes
boolean
C0011854 (UMLS CUI [1])
C0011849 (UMLS CUI [2,1])
C0678226 (UMLS CUI [2,2])
C0273163 (UMLS CUI [2,3])
C0271640 (UMLS CUI [3])
Fibrates | Thiazolidinediones | Insulin
Item
current treatment with fibrates, thiazolidinediones, or insulin
boolean
C1449704 (UMLS CUI [1])
C1257987 (UMLS CUI [2])
C0021641 (UMLS CUI [3])
Intolerance to Thiazolidinediones | Intolerance to Fibrates
Item
prior intolerance to thiazolidinediones and/or fibrates
boolean
C1744706 (UMLS CUI [1,1])
C1257987 (UMLS CUI [1,2])
C1744706 (UMLS CUI [2,1])
C1449704 (UMLS CUI [2,2])
Liver disease | Liver Dysfunction
Item
clinically significant liver disease or impaired liver function
boolean
C0023895 (UMLS CUI [1])
C0086565 (UMLS CUI [2])
Complications of Diabetes Mellitus chronic | Retinal Disease | Neuropathy | Kidney Disease
Item
know chronic diabetic complications (i.e. retinopathy, neuropathy, nephropathy)
boolean
C0342257 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C0035309 (UMLS CUI [2])
C0442874 (UMLS CUI [3])
C0022658 (UMLS CUI [4])
Symptomatic congestive heart failure New York Heart Association Classification
Item
symptomatic congestive heart failure classified as nyha class ii-iv
boolean
C0742758 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Malignant Neoplasms | Cancer treatment | Exception Basal cell carcinoma Treated | Exception Carcinoma in situ of uterine cervix Treated | Exception Carcinoma in situ of prostate Treated
Item
diagnosed and/or treated malignancy within the past 5 years, except for treated basal cell skin cancer, in situ carcinoma of the cervix, or in situ prostate cancer
boolean
C0006826 (UMLS CUI [1])
C0920425 (UMLS CUI [2])
C1705847 (UMLS CUI [3,1])
C0007117 (UMLS CUI [3,2])
C1522326 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C0851140 (UMLS CUI [4,2])
C1522326 (UMLS CUI [4,3])
C1705847 (UMLS CUI [5,1])
C0154088 (UMLS CUI [5,2])
C1522326 (UMLS CUI [5,3])
Medical contraindication MRI | MRI scan Receive Unable
Item
contraindications to mri, or inability to tolerate mri scanning
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0024485 (UMLS CUI [2,1])
C1514756 (UMLS CUI [2,2])
C1299582 (UMLS CUI [2,3])