Adenocarcinoma of lung | Large cell carcinoma of lung | Bronchioloalveolar Non-Small Cell Lung Carcinoma
Item
histologically or cytologically confirmed diagnosis of adeno-, large cell or bronchioalveolar non-small cell lung cancer
boolean
C0152013 (UMLS CUI [1])
C0345958 (UMLS CUI [2])
C0007120 (UMLS CUI [3,1])
C0007131 (UMLS CUI [3,2])
Cytologic material Cell type Classification | Bronchial brush biopsy | Bronchial washing | Lesion Fine needle aspiration
Item
cytologic specimens for diagnosis or for cell type classification must have been obtained from bronchial brushings or washings or from needle aspiration of a defined lesion. sputum cytology alone will not be acceptable for diagnosis or for cell type classification.
boolean
C0225355 (UMLS CUI [1,1])
C0449475 (UMLS CUI [1,2])
C0008902 (UMLS CUI [1,3])
C2370811 (UMLS CUI [2])
C0396473 (UMLS CUI [3])
C0221198 (UMLS CUI [4,1])
C1510483 (UMLS CUI [4,2])
Non-Small Cell Lung Carcinoma Mixed Ineligible | Squamous non-small cell lung cancer Ineligible
Item
patients with mixed nsclc with predominantly squamous cell carcinoma should be classified as squamous and thus do not qualify for this study.
boolean
C0007131 (UMLS CUI [1,1])
C0205430 (UMLS CUI [1,2])
C1512714 (UMLS CUI [1,3])
C4509816 (UMLS CUI [2,1])
C1512714 (UMLS CUI [2,2])
TNM clinical staging | Pleural Effusion, Malignant | Malignant pericardial effusion | Recurrent disease | Status post Therapy Locoregional
Item
stage iiib with malignant effusion (with cytologic confirmation of malignant pleural or pericardial effusion), stage iv, or recurrent disease after definitive loco-regional therapy.
boolean
C3258246 (UMLS CUI [1])
C0080032 (UMLS CUI [2])
C0220655 (UMLS CUI [3])
C0277556 (UMLS CUI [4])
C0231290 (UMLS CUI [5,1])
C0087111 (UMLS CUI [5,2])
C1947913 (UMLS CUI [5,3])
Patient Appropriate Primary treatment | Cisplatin | pemetrexed
Item
candidate for primary treatment with cisplatin and pemetrexed
boolean
C0030705 (UMLS CUI [1,1])
C1548787 (UMLS CUI [1,2])
C1708063 (UMLS CUI [1,3])
C0008838 (UMLS CUI [2])
C0210657 (UMLS CUI [3])
Squamous non-small cell lung cancer predominant
Item
any histological/cytological evidence of predominantly squamous nsclc.
boolean
C4509816 (UMLS CUI [1,1])
C1542147 (UMLS CUI [1,2])
Small cell carcinoma of lung | Carcinoid tumor of lung
Item
small cell or carcinoid lung cancer patients are also ineligible.
boolean
C0149925 (UMLS CUI [1])
C0280089 (UMLS CUI [2])
Non-Small Cell Lung Carcinoma Without Histology Eligible
Item
nsclc that cannot be classified as one of the eligible histologies (adenocarcinoma, large cell or bronchioalveolar).
boolean
C0007131 (UMLS CUI [1,1])
C0332288 (UMLS CUI [1,2])
C4048239 (UMLS CUI [1,3])
C1548635 (UMLS CUI [1,4])
Systemic therapy TNM clinical staging | Systemic therapy Malignant Effusion | Systemic therapy Non-small cell lung cancer recurrent
Item
prior systemic therapy for stage iiib (with malignant effusion), stage iv, or recurrent nsclc. (prior treatment with systemic therapy as adjuvant chemotherapy or in conjunction with radiotherapy for stage ii or iii nsclc is permitted if the last dose of chemotherapy was completed 12 months or more prior to randomization).
boolean
C1515119 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
C1515119 (UMLS CUI [2,1])
C0080032 (UMLS CUI [2,2])
C1515119 (UMLS CUI [3,1])
C0278517 (UMLS CUI [3,2])
VEGF Inhibitor | VEGFR Inhibitor
Item
prior treatment with a vegf or vegfr inhibitor.
boolean
C4521299 (UMLS CUI [1])
C2985521 (UMLS CUI [2])