Age
Item
males and females between the ages of 18-75.
boolean
C0001779 (UMLS CUI [1])
Comprehension Study Protocol | Informed Consent | Compliance behavior Follow-up
Item
subject understands protocol and provides written, informed consent in addition to a willingness to comply with specified follow-up evaluations.
boolean
C0162340 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])
C0021430 (UMLS CUI [2])
C1321605 (UMLS CUI [3,1])
C3274571 (UMLS CUI [3,2])
Pregnancy | Breast Feeding
Item
pregnancy or women currently breastfeeding.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Body mass index
Item
bmi less than 18.5
boolean
C1305855 (UMLS CUI [1])
Body Weight Unstable
Item
subjects with unstable weight that varies greater than 10% over the past 3 months.
boolean
C0005910 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
Fat-Restricted Diet
Item
subjects currently following any low-fat (< 20%) diet.
boolean
C0242970 (UMLS CUI [1])
Consumption Routine Number of meals per day | Consumption Routine Number of snacks per day
Item
subjects that routinely consume less than 3 meals/snacks per day
boolean
C0009830 (UMLS CUI [1,1])
C0205547 (UMLS CUI [1,2])
C2008797 (UMLS CUI [1,3])
C0009830 (UMLS CUI [2,1])
C0205547 (UMLS CUI [2,2])
C2008798 (UMLS CUI [2,3])
Soluble fiber supplementation | Bile acid sequestrants | Phytosterol Supplements | Antibiotics | Anticoagulants | Anticonvulsants | Anti-Arrhythmia Agents | Cyclosporine | Mycophenolate | Synthroid | Vitamin A | Vitamin E | Vitamin K
Item
subjects taking the following medications, which may show reduced absorption with alpha-cd or may otherwise interfere with the study will be excluded: soluble fiber supplements, bas, plant sterol supplements, antibiotics, anticoagulants, anticonvulsants, antiarrhytmics , cyclosporine, mycophenolate, synthroid, vitamin a, e and k and or any drug that is necessary to take with a meal. if any of these medications are initiated during the study, the subjects will be instructed to discontinue the use of the alpha-cd or placebo pills and to withdraw from the study. short-term and prophylactic antibiotics may be taken during study participation for up to 14 days, at least 2 hours apart from the study drug.
boolean
C0556108 (UMLS CUI [1])
C2917337 (UMLS CUI [2])
C0031866 (UMLS CUI [3,1])
C0242295 (UMLS CUI [3,2])
C0003232 (UMLS CUI [4])
C0003280 (UMLS CUI [5])
C0003286 (UMLS CUI [6])
C0003195 (UMLS CUI [7])
C0010592 (UMLS CUI [8])
C0883242 (UMLS CUI [9])
C0728762 (UMLS CUI [10])
C0042839 (UMLS CUI [11])
C0042874 (UMLS CUI [12])
C0042878 (UMLS CUI [13])
Chronic diarrhea | Gastric Bypass | Gastric band Procedure | Ostomy | Motility disorder of intestine | Condition Affecting Intestinal fat absorption
Item
subjects with chronic diarrhea, gastric bypass or lapband procedures, ostomies, bowel motility problems, or other conditions that could affect intestinal fat absorption.
boolean
C0401151 (UMLS CUI [1])
C0017125 (UMLS CUI [2])
C3854330 (UMLS CUI [3,1])
C0184661 (UMLS CUI [3,2])
C0029473 (UMLS CUI [4])
C0400865 (UMLS CUI [5])
C0348080 (UMLS CUI [6,1])
C0392760 (UMLS CUI [6,2])
C0232653 (UMLS CUI [6,3])
New medications | Pharmaceutical Preparations multiple
Item
subjects initiating new medications or patients on multiple medications may also be excluded.
boolean
C1718097 (UMLS CUI [1])
C0013227 (UMLS CUI [2,1])
C0439064 (UMLS CUI [2,2])
Diabetes Mellitus, Insulin-Dependent | Diabetes Mellitus, Non-Insulin-Dependent
Item
patients with type i or type ii diabetes.
boolean
C0011854 (UMLS CUI [1])
C0011860 (UMLS CUI [2])
alpha-cyclodextrin
Item
subjects currently taking alpha-cd in its commercial form.
boolean
C0051348 (UMLS CUI [1])
Condition Interferes with Research results | Disease Interferes with Research results | Condition At risk Patient safety | Disease At risk Patient safety
Item
volunteers may also be excluded, if in the opinion of the study investigators, they have some other condition or disorder that may adversely affect the outcome of the study or the safety of the volunteer.
boolean
C0348080 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0683954 (UMLS CUI [1,3])
C0012634 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0683954 (UMLS CUI [2,3])
C0348080 (UMLS CUI [3,1])
C1444641 (UMLS CUI [3,2])
C1113679 (UMLS CUI [3,3])
C0012634 (UMLS CUI [4,1])
C1444641 (UMLS CUI [4,2])
C1113679 (UMLS CUI [4,3])