Age | Capability Informed Consent
Item
at least 18 years of age and capable of giving informed consent
boolean
C0001779 (UMLS CUI [1])
C2698977 (UMLS CUI [2,1])
C0021430 (UMLS CUI [2,2])
Renal Cell Carcinoma CT scan TNM clinical staging | Neoplasm Metastasis
Item
radiological evidence of rcc consisting of: ct scan with stage t2, t3, t3a, t3b, t4, or any stage t with n1/ 2 and/ or metastatic disease
boolean
C0007134 (UMLS CUI [1,1])
C0040405 (UMLS CUI [1,2])
C3258246 (UMLS CUI [1,3])
C0027627 (UMLS CUI [2])
Nephrectomy | Kidney biopsy Willing
Item
having a nephrectomy and willing to have a kidney biopsy
boolean
C0027695 (UMLS CUI [1])
C0194073 (UMLS CUI [2,1])
C0600109 (UMLS CUI [2,2])
ECOG performance status
Item
ecog score 0 or 1
boolean
C1520224 (UMLS CUI [1])
Clear cell Histology
Item
clear cell histology
boolean
C0229473 (UMLS CUI [1,1])
C0344441 (UMLS CUI [1,2])
HIV negative | Hepatitis B test negative | Hepatitis C test negative
Item
negative for hiv, hepatitis b, and hepatitis c
boolean
C0481430 (UMLS CUI [1])
C1611173 (UMLS CUI [2])
C1619717 (UMLS CUI [3])
Childbearing Potential Pregnancy test negative
Item
negative pregnancy test for women of child-bearing potential
boolean
C3831118 (UMLS CUI [1,1])
C0427780 (UMLS CUI [1,2])
Disease TNM clinical staging | Neoplasm Metastasis Absent
Item
stage t1 disease without metastases
boolean
C0012634 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
C0027627 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Laboratory test result abnormal
Item
abnormal laboratory values at screening within the following ranges:
boolean
C0438215 (UMLS CUI [1])
Absolute neutrophil count | Platelet Count measurement
Item
absolute neutrophil count ≤ 1.5 × 109/ l; platelet count ≤ 100 × 109/ l
boolean
C0948762 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
White Blood Cell Count procedure | Hemoglobin measurement | Serum creatinine raised | Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement
Item
leukocyte count ≤ 3 × 109/ l; hemoglobin ≤ 80 g/ l; serum creatinine ≥ 2.0 × the upper normal limit (unl); total bilirubin ≤ 1.5 × unl; ast and alt ≤ 3.0 × unl
boolean
C0023508 (UMLS CUI [1])
C0518015 (UMLS CUI [2])
C0700225 (UMLS CUI [3])
C1278039 (UMLS CUI [4])
C0201899 (UMLS CUI [5])
C0201836 (UMLS CUI [6])
Fasting cholesterol level | Serum fasting triglyceride measurement
Item
fasting serum cholesterol ≤ 9.0 mmol/ l; fasting serum triglycerides ≥ 5.0 mmol/l
boolean
C1282513 (UMLS CUI [1])
C0582824 (UMLS CUI [2])
Illness Major Study Subject Participation Status At risk
Item
any major illness that, based on the investigator's judgment, will substantially increase the risk associated with a subject's participation in this study
boolean
C0221423 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
C2348568 (UMLS CUI [1,3])
C1444641 (UMLS CUI [1,4])
Cancer Other
Item
other currently active malignancies
boolean
C1707251 (UMLS CUI [1])
Pharmaceutical Preparations Interfere with Metabolism Everolimus
Item
currently taking any medications known to interfere with the metabolism of everolimus
boolean
C0013227 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0025519 (UMLS CUI [1,3])
C0541315 (UMLS CUI [1,4])
Anticoagulation Therapy | Warfarin
Item
receiving anticoagulation with warfarin
boolean
C0003281 (UMLS CUI [1])
C0043031 (UMLS CUI [2])
Pulmonary Hypertension | Lung Disease, Interstitial
Item
a history of pulmonary hypertension or interstitial lung disease
boolean
C0020542 (UMLS CUI [1])
C0206062 (UMLS CUI [2])