Age
Item
age ≥ 18
boolean
C0001779 (UMLS CUI [1])
Karnofsky Performance Status
Item
karnofsky performance status of ≥ 60
boolean
C0206065 (UMLS CUI [1])
Carcinoma intrahepatic | Liver carcinoma
Item
pathologically confirmed ihc or hcc. (pathology not required for hcc if the lesion enhances typically on mri and the patient is evaluated by liver transplant surgery team and thought to have hcc.)
boolean
C0007097 (UMLS CUI [1,1])
C1512948 (UMLS CUI [1,2])
C2239176 (UMLS CUI [2])
Lesion intrahepatic
Item
4 or less separate intrahepatic lesions, with at least one lesion that is able to be followed by easl criteria.
boolean
C0221198 (UMLS CUI [1,1])
C1512948 (UMLS CUI [1,2])
Local excision Unsuccessful
Item
local surgical resection is not possible due to tumor or patient factors
boolean
C0278259 (UMLS CUI [1,1])
C1272705 (UMLS CUI [1,2])
Neoplasm Metastasis Limited
Item
limited metastatic disease is allowed if the volume of metastatic disease does not exceed the volume of primary disease.
boolean
C0027627 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
Transarterial Chemoembolization Discontinued | Transarterial Chemoembolization Completed
Item
prior tace allowed if stopped/completed at least 2 weeks prior to enrollment
boolean
C3539919 (UMLS CUI [1,1])
C1444662 (UMLS CUI [1,2])
C3539919 (UMLS CUI [2,1])
C0205197 (UMLS CUI [2,2])
Prior Chemotherapy Discontinued | Prior Chemotherapy Completed | Exception Sorafenib
Item
prior chemotherapy except sorafenib allowed if stopped/completed at least 2 weeks prior to enrollment
boolean
C1514457 (UMLS CUI [1,1])
C1444662 (UMLS CUI [1,2])
C1514457 (UMLS CUI [2,1])
C0205197 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C1516119 (UMLS CUI [3,2])
Sorafenib Discontinued | Sorafenib Completed
Item
prior sorafenib allowed if stopped/completed at least seven days prior to enrollment.
boolean
C1516119 (UMLS CUI [1,1])
C1444662 (UMLS CUI [1,2])
C1516119 (UMLS CUI [2,1])
C0205197 (UMLS CUI [2,2])
Informed Consent
Item
able to provide signed informed consent
boolean
C0021430 (UMLS CUI [1])
Child-Pugh Classification
Item
childs-pugh score 9 or more
boolean
C2347612 (UMLS CUI [1])
Alanine aminotransferase increased | Aspartate aminotransferase increased
Item
alt or ast ≥ 6 x upper limit of normal
boolean
C0151905 (UMLS CUI [1])
C0151904 (UMLS CUI [2])
Radiotherapy to abdomen
Item
prior history of abdominal irradiation
boolean
C1997554 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
women who are pregnant or nursing
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Chemotherapy Scheduled | Exception Sorafenib
Item
scheduled to undergo chemotherapy except sorafenib at the time when radiation therapy will be given, or for up to 4 weeks after completion of radiation therapy.
boolean
C0392920 (UMLS CUI [1,1])
C0205539 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C1516119 (UMLS CUI [2,2])
Sorafenib Scheduled
Item
scheduled to undergo sorafenib within seven days of when radiation therapy will be delivered, or for up to 2 weeks after completion of radiation therapy.
boolean
C1516119 (UMLS CUI [1,1])
C0205539 (UMLS CUI [1,2])
Radiotherapy to abdomen
Item
undergone prior radiation therapy to the abdomen.
boolean
C1997554 (UMLS CUI [1])