Breast Carcinoma TNM Breast tumor staging | First line Adjuvant therapy | First line Neoadjuvant Therapy | Paclitaxel | docetaxel
Item
patients (men and women) diagnosed with breast cancer stages i-iii initiating first line adjuvant or neoadjuvant therapy with paclitaxel or docetaxel
boolean
C0678222 (UMLS CUI [1,1])
C0474926 (UMLS CUI [1,2])
C1708063 (UMLS CUI [2,1])
C0677850 (UMLS CUI [2,2])
C1708063 (UMLS CUI [3,1])
C0600558 (UMLS CUI [3,2])
C0144576 (UMLS CUI [4])
C0246415 (UMLS CUI [5])
Informed Consent
Item
ability to understand and the willingness to sign a written informed consent document.
boolean
C0021430 (UMLS CUI [1])
Functional Limitation Due to Musculoskeletal problem
Item
patients with functional limitations due to musculoskeletal conditions can be included, because these conditions are known to remain stable over the relatively short duration of the study.
boolean
C4542603 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0026859 (UMLS CUI [1,3])
Standard Pharmaceutical Preparations | Investigational New Drugs | Standard Chemotherapeutic Agents
Item
concurrent standard and investigational agents are permissible with the standard chemotherapy drugs.
boolean
C1442989 (UMLS CUI [1,1])
C0013227 (UMLS CUI [1,2])
C0013230 (UMLS CUI [2])
C1442989 (UMLS CUI [3,1])
C0003392 (UMLS CUI [3,2])
Prior Chemotherapy Breast Carcinoma | Targeted Therapy Breast Carcinoma | Prior Chemotherapy Cancer Other Associated with Neuropathy | Targeted Therapy Cancer Other Associated with Neuropathy | Platinum Therapy | bortezomib | Vinblastine
Item
prior known chemotherapy or targeted therapy (for breast cancer or other malignancies that is known to be associated with neuropathy in the last 12 months(platinum therapy, bortezomib, vinblastine, etc.)
boolean
C1514457 (UMLS CUI [1,1])
C0678222 (UMLS CUI [1,2])
C2985566 (UMLS CUI [2,1])
C0678222 (UMLS CUI [2,2])
C1514457 (UMLS CUI [3,1])
C1707251 (UMLS CUI [3,2])
C0332281 (UMLS CUI [3,3])
C0442874 (UMLS CUI [3,4])
C2985566 (UMLS CUI [4,1])
C1707251 (UMLS CUI [4,2])
C0332281 (UMLS CUI [4,3])
C0442874 (UMLS CUI [4,4])
C0032207 (UMLS CUI [5,1])
C0087111 (UMLS CUI [5,2])
C1176309 (UMLS CUI [6])
C0042670 (UMLS CUI [7])
Exposure to Taxane
Item
prior taxane exposure at any time
boolean
C0332157 (UMLS CUI [1,1])
C0215136 (UMLS CUI [1,2])
Neuropathy Type Any
Item
preexisting known diagnosis of any type of neuropathy prior to start of paclitaxel or docetaxel chemotherapy
boolean
C0442874 (UMLS CUI [1,1])
C0332307 (UMLS CUI [1,2])
C1552551 (UMLS CUI [1,3])
Pregnancy | Breast Feeding
Item
pregnant or nursing women.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Informed Consent Unable
Item
unable to give informed consent.
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Amputation of lower limb Pre-existing
Item
preexisting lower extremity amputation
boolean
C0337308 (UMLS CUI [1,1])
C2347662 (UMLS CUI [1,2])
Difficulty walking unassisted | Lacking Able to stand alone | Etiology Condition Any
Item
inability to walk or stand without assistance due to any condition
boolean
C2183457 (UMLS CUI [1])
C0332268 (UMLS CUI [2,1])
C0560202 (UMLS CUI [2,2])
C0015127 (UMLS CUI [3,1])
C0348080 (UMLS CUI [3,2])
C1552551 (UMLS CUI [3,3])
Drugs used in neuropathic pain | gabapentin | pregabalin | Amitriptyline | duloxetine
Item
neuropathic pain medications prior to start of study including gabapentin, pregabalin, amytriptyline, and duloxetine (but initiation of neuropathic pain medications during treatment are permissible)
boolean
C1319667 (UMLS CUI [1])
C0060926 (UMLS CUI [2])
C0657912 (UMLS CUI [3])
C0002600 (UMLS CUI [4])
C0245561 (UMLS CUI [5])
Patient need for Walking assistive device
Item
patients needing ambulatory assist devices
boolean
C0686904 (UMLS CUI [1,1])
C3874140 (UMLS CUI [1,2])
Back surgery | Surgical procedure on lower extremity
Item
back or lower extremity surgery in the last 6 months
boolean
C0741419 (UMLS CUI [1])
C0187763 (UMLS CUI [2])
Back surgery Interferes with Gait | Surgical procedure on lower extremity Interferes with Gait | Back surgery Interferes with Balance | Surgical procedure on lower extremity Interferes with Balance
Item
back or lower extremity surgery at any timepoint that interferes with gait and balance per patient or provider report
boolean
C0741419 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0016928 (UMLS CUI [1,3])
C0187763 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0016928 (UMLS CUI [2,3])
C0741419 (UMLS CUI [3,1])
C0521102 (UMLS CUI [3,2])
C0014653 (UMLS CUI [3,3])
C0187763 (UMLS CUI [4,1])
C0521102 (UMLS CUI [4,2])
C0014653 (UMLS CUI [4,3])