Hormone Receptor Positive
Item
1. hormone receptor positive;
boolean
C0019929 (UMLS CUI [1,1])
C1514241 (UMLS CUI [1,2])
Patients Untreated | Hormone Therapy Absent | Hormone Therapy Initial failed | First line Hormone Therapy failed Relapse | First line Hormone Therapy failed Neoplasm Metastasis
Item
2. previously untreated patients who do not receive hormonal therapy, or initial endocrine treatment failure or first -line endocrine treatment of relapse and metastasis failure;
boolean
C0030705 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
C0279025 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0279025 (UMLS CUI [3,1])
C0205265 (UMLS CUI [3,2])
C0231175 (UMLS CUI [3,3])
C1708063 (UMLS CUI [4,1])
C0279025 (UMLS CUI [4,2])
C0231175 (UMLS CUI [4,3])
C0035020 (UMLS CUI [4,4])
C1708063 (UMLS CUI [5,1])
C0279025 (UMLS CUI [5,2])
C0231175 (UMLS CUI [5,3])
C0027627 (UMLS CUI [5,4])
Hormone Therapy Absent | Invasive Ductal Breast Carcinoma | Operative Surgical Procedures | Elderly | Cardiac complication Severe | Severe medical complication Systemic | High risk of General Anesthesia | Breast Conservation Willing | Large tumor Inappropriate Breast-Conserving Surgery
Item
3. patients who do not receive hormonal therapy must be histologically confirmed invasive ductal carcinoma, can be surgery, but must be satisfied one of the following: (1) elderly (≥70 years), or with severe heart or other systemic complications, belonging to high risk of general anesthesia, (2) have will of conserving the breast,but larger tumors (≥3cm) not suitable for breast-conserving surgery.
boolean
C0279025 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1134719 (UMLS CUI [2])
C0543467 (UMLS CUI [3])
C0001792 (UMLS CUI [4])
C0161816 (UMLS CUI [5,1])
C0205082 (UMLS CUI [5,2])
C3495031 (UMLS CUI [6,1])
C0205373 (UMLS CUI [6,2])
C0332167 (UMLS CUI [7,1])
C0002915 (UMLS CUI [7,2])
C0006141 (UMLS CUI [8,1])
C2347858 (UMLS CUI [8,2])
C0600109 (UMLS CUI [8,3])
C0475278 (UMLS CUI [9,1])
C1548788 (UMLS CUI [9,2])
C0917927 (UMLS CUI [9,3])
Secondary malignant neoplasm of female breast | Lesions Evaluable
Item
4. patients with metastatic breast cancer must have evaluable lesions
boolean
C0346993 (UMLS CUI [1])
C0221198 (UMLS CUI [2,1])
C1516986 (UMLS CUI [2,2])
Normal Laboratory Test Result
Item
5. normal laboratory values:
boolean
C0438214 (UMLS CUI [1])
Informed Consent
Item
6. informed consent (ethical approval document no. :1112105-1);
boolean
C0021430 (UMLS CUI [1])
Life Expectancy
Item
7. life expectancy of at least 3 months;
boolean
C0023671 (UMLS CUI [1])
Postmenopausal state | Premenopausal state | Bilateral oophorectomy
Item
8. postmenopausal or premenopausal with bilateral oophorectomy.
boolean
C0232970 (UMLS CUI [1])
C0232969 (UMLS CUI [2])
C0278321 (UMLS CUI [3])
Therapeutic radiology procedure | Local Therapy Measurable lesion
Item
1. have had radiotherapy or other local treatment for measurable lesions before the start of study received within 3 months
boolean
C1522449 (UMLS CUI [1])
C1517925 (UMLS CUI [2,1])
C1513041 (UMLS CUI [2,2])
Organ Transplantation | Exception Autologous bone marrow transplant | Exception Allogeneic bone marrow transplantation
Item
2. organ transplant (except for autologous or allogeneic bone marrow transplantation);
boolean
C0029216 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0194037 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0149615 (UMLS CUI [3,2])
CNS metastases | Mental disorder Uncontrolled
Item
3. have evidences of central nerve system metastases or have a history of mental illness that uncontrol;
boolean
C0686377 (UMLS CUI [1])
C0004936 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
Lacking Able to swallow Tablets | Malabsorption | Upper Gastrointestinal Tract Integrity Poor
Item
4. unable to swallow tablets, or malabsorption patients, or patients with poor upper gastrointestinal integrity;
boolean
C0332268 (UMLS CUI [1,1])
C2712086 (UMLS CUI [1,2])
C0039225 (UMLS CUI [1,3])
C3714745 (UMLS CUI [2])
C3203348 (UMLS CUI [3,1])
C1947912 (UMLS CUI [3,2])
C2700379 (UMLS CUI [3,3])
Protocol Compliance Unwilling | Protocol Compliance Unable | Follow-up Fulfill Unable
Item
5. unwilling or unable to comply with study protocol or unable to meet the follow up;
boolean
C0525058 (UMLS CUI [1,1])
C0558080 (UMLS CUI [1,2])
C0525058 (UMLS CUI [2,1])
C1299582 (UMLS CUI [2,2])
C3274571 (UMLS CUI [3,1])
C1550543 (UMLS CUI [3,2])
C1299582 (UMLS CUI [3,3])
Study Subject Participation Status Inappropriate
Item
6. patients who researchers considered were not suitable to participate.
boolean
C2348568 (UMLS CUI [1,1])
C1548788 (UMLS CUI [1,2])