age at least 18 Years
Item
Alter mindestens 18 Jahre
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
Chorea Huntington (CAG repeats >39)
Item
Chorea Huntington (CAG repeats >39)
boolean
C0020179 (UMLS CUI 2011AA)
58756001 (SNOMED CT 2011_0131)
10070668 (MedDRA 14.1)
G10 (ICD-10-CM Version 2010)
333.4 (ICD-9-CM Version 2011)
C0011900 (UMLS CUI 2011AA)
439401001 (SNOMED CT 2011_0131)
MTHU008876 (LOINC Version 232)
C2751801 (UMLS CUI 2011AA)
C1547730 (UMLS CUI 2011AA)
UHDRS TFC >5
Item
UHDRS TFC >5
boolean
C1706076 (UMLS CUI 2011AA)
C0020179 (UMLS CUI 2011AA)
58756001 (SNOMED CT 2011_0131)
10070668 (MedDRA 14.1)
G10 (ICD-10-CM Version 2010)
333.4 (ICD-9-CM Version 2011)
C0681889 (UMLS CUI 2011AA)
C0439810 (UMLS CUI 2011AA)
255619001 (SNOMED CT 2011_0131)
C0205245 (UMLS CUI 2011AA)
40143009 (SNOMED CT 2011_0131)
C1516240 (UMLS CUI 2011AA)
C0449820 (UMLS CUI 2011AA)
246262008 (SNOMED CT 2011_0131)
MTHU024701 (LOINC Version 232)
Normal liver function laboratory test
Item
Normal liver function laboratory test
boolean
C1848676 (UMLS CUI 2011AA)
C0022885 (UMLS CUI 2011AA)
15220000 (SNOMED CT 2011_0131)
10059938 (MedDRA 14.1)
Stable concomitant medication regimen > 4 weeks prior to Baseline
Item
Stable concomitant medication regimen > 4 weeks prior to Baseline
boolean
C0205360 (UMLS CUI 2011AA)
58158008 (SNOMED CT 2011_0131)
MTHU015276 (LOINC Version 232)
C2347852 (UMLS CUI 2011AA)
CL031856 (UMLS CUI 2011AA)
C0332152 (UMLS CUI 2011AA)
288556008 (SNOMED CT 2011_0131)
C1442488 (UMLS CUI 2011AA)
Motivation for women with childbearing potential to use highly efficient contraception
Item
Motivation for women with childbearing potential to use highly efficient contraception
boolean
C0043210 (UMLS CUI 2011AA)
224526002 (SNOMED CT 2011_0131)
C1148523 (UMLS CUI 2011AA)
C0237399 (UMLS CUI 2011AA)
C0026605 (UMLS CUI 2011AA)
363882003 (SNOMED CT 2011_0131)
C0700589 (UMLS CUI 2011AA)
146680009 (SNOMED CT 2011_0131)
10010808 (MedDRA 14.1)
Clinically relevant abnormal findings in the ECG, vital signs, physical examination or laboratory values at Screening,
Item
Clinically relevant abnormal findings in the ECG, vital signs, physical examination or laboratory values at Screening,
boolean
C2826279 (UMLS CUI 2011AA)
C1623258 (UMLS CUI 2011AA)
46825001 (SNOMED CT 2011_0131)
10014084 (MedDRA 14.1)
C0518766 (UMLS CUI 2011AA)
46680005 (SNOMED CT 2011_0131)
MTHU024540 (LOINC Version 232)
C0031809 (UMLS CUI 2011AA)
5880005 (SNOMED CT 2011_0131)
10034986 (MedDRA 14.1)
MTHU028014 (LOINC Version 232)
89.7 (ICD-9-CM Version 2011)
C0022877 (UMLS CUI 2011AA)
261904005 (SNOMED CT 2011_0131)
MTHU029808 (LOINC Version 232)
C1522609 (UMLS CUI 2011AA)
Long-term treatment with potentially hepatoxic medication
Item
Long-term treatment with potentially hepatoxic medication
boolean
C0443252 (UMLS CUI 2011AA)
C0039798 (UMLS CUI 2011AA)
CL415205 (UMLS CUI 2011AA)
C0235378 (UMLS CUI 2011AA)
10019851 (MedDRA 14.1)
C0013227 (UMLS CUI 2011AA)
Any unstable medical condition
Item
Any unstable medical condition
boolean
C0443343 (UMLS CUI 2011AA)
263922001 (SNOMED CT 2011_0131)
C1699700 (UMLS CUI 2011AA)
MEDCCAT (HL7 V3 2006_05)
Depression (BDI Depression score > 9)
Item
Depression (BDI Depression score > 9)
boolean
C0011581 (UMLS CUI 2011AA)
35489007 (SNOMED CT 2011_0131)
10012401 (MedDRA 14.1)
F32.9 (ICD-10-CM Version 2010)
C2960571 (UMLS CUI 2011AA)
446053003 (SNOMED CT 2011_0131)
Cognitive dysfunction defined as a score < 23 in the Mini-Mental State Examination (MMSE) at Screening
Item
Cognitive dysfunction defined as a score < 23 in the Mini-Mental State Examination (MMSE) at Screening
boolean
C0338656 (UMLS CUI 2011AA)
386806002 (SNOMED CT 2011_0131)
10009846 (MedDRA 14.1)
C1704788 (UMLS CUI 2011AA)
C0449820 (UMLS CUI 2011AA)
246262008 (SNOMED CT 2011_0131)
MTHU024701 (LOINC Version 232)
C0451306 (UMLS CUI 2011AA)
273617000 (SNOMED CT 2011_0131)
10067001 (MedDRA 14.1)
Liver or renal disease
Item
Liver or renal disease
boolean
C0023895 (UMLS CUI 2011AA)
235856003 (SNOMED CT 2011_0131)
10024670 (MedDRA 14.1)
K76.9 (ICD-10-CM Version 2010)
573.9 (ICD-9-CM Version 2011)
C0022658 (UMLS CUI 2011AA)
90708001 (SNOMED CT 2011_0131)
10029151 (MedDRA 14.1)
N18.9 (ICD-10-CM Version 2010)
Consumption of > two cups of black tea per day, consumption of green tea, consumption of > 500 ml /day of grapefruit juice
Item
Consumption of > two cups of black tea per day, consumption of green tea, consumption of > 500 ml /day of grapefruit juice
boolean
C1947907 (UMLS CUI 2011AA)
C0439505 (UMLS CUI 2011AA)
259032004 (SNOMED CT 2011_0131)
C0452440 (UMLS CUI 2011AA)
226476000 (SNOMED CT 2011_0131)
C0795620 (UMLS CUI 2011AA)
C0452456 (UMLS CUI 2011AA)
226493000 (SNOMED CT 2011_0131)