Age
Item
Is the participant greater or equal to 35 years of age?
boolean
C0001779 (UMLS CUI [1])
Unilateral/Bilateral Emphysema on CT
Item
Does the participant have a high resolution CT scan that indicates unilateral or bilateral emphysema?
boolean
C0412612 (UMLS CUI [1,1])
C3508932 (UMLS CUI [1,2])
C0412612 (UMLS CUI [2,1])
C0034067 (UMLS CUI [2,2])
C0238767 (UMLS CUI [2,3])
Homogeneous/Heterogeneous Emphysema on CT
Item
Does the participant have a high resolution CT scan that indicates homogeneous or heterogeneous emphysema?
boolean
C0412612 (UMLS CUI [1,1])
C0439713 (UMLS CUI [1,2])
C0034067 (UMLS CUI [1,3])
C0412612 (UMLS CUI [2,1])
C0019409 (UMLS CUI [2,2])
C0034067 (UMLS CUI [2,3])
Post-bronchodilator FEV1
Item
Does the participant have a post-bronchodilator FEV1 less than or equal to 45% predicted?
boolean
C2599594 (UMLS CUI [1,1])
C0849974 (UMLS CUI [1,2])
C0439092 (UMLS CUI [1,3])
C0681842 (UMLS CUI [1,4])
Total Lung Capacity
Item
Does the participant have a Total Lung Capacity greater than 100% predicted?
boolean
C0040509 (UMLS CUI [1,1])
C0439093 (UMLS CUI [1,2])
C0681842 (UMLS CUI [1,3])
Marked Dyspnea
Item
Does the participant have a marked dyspnea scoring greater than or equal to 2 on mMRC scale of 0-4?
boolean
C1706089 (UMLS CUI [1,1])
C0013404 (UMLS CUI [1,2])
C4055397 (UMLS CUI [1,3])
Stopped Smoking
Item
Does the participant have stopped smoking for a minimum of 8 weeks prior to entering the study?
boolean
C0425310 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
C0332152 (UMLS CUI [1,3])
C2603343 (UMLS CUI [1,4])
Informed Consent
Item
Does the participant (and legal guardian if applicable) have read, understood and signed the Informed Consent form
boolean
C0679646 (UMLS CUI [1,1])
C0034754 (UMLS CUI [1,2])
C0009797 (UMLS CUI [1,3])
C0679646 (UMLS CUI [2,1])
C0162340 (UMLS CUI [2,2])
C0009797 (UMLS CUI [2,3])
C0679646 (UMLS CUI [3,1])
C1519316 (UMLS CUI [3,2])
C0009797 (UMLS CUI [3,3])
C0023226 (UMLS CUI [4,1])
C0034754 (UMLS CUI [4,2])
C0009797 (UMLS CUI [4,3])
C0023226 (UMLS CUI [5,1])
C0162340 (UMLS CUI [5,2])
C0009797 (UMLS CUI [5,3])
C0023226 (UMLS CUI [6,1])
C1519316 (UMLS CUI [6,2])
C0009797 (UMLS CUI [6,3])
Post-Bronchodliator FEV1 change
Item
Does the participant have a change in FEV1 greater than 20% post-bronchodilator?
boolean
C2599594 (UMLS CUI [1,1])
C0849974 (UMLS CUI [1,2])
C4319952 (UMLS CUI [1,3])
C0439093 (UMLS CUI [1,4])
DLCO
Item
Does the participant have a DLCO less than 20% predicted?
boolean
C1516251 (UMLS CUI [1,1])
C0439092 (UMLS CUI [1,2])
C0681842 (UMLS CUI [1,3])
Recurrent respiratory infection
Item
Does the participant have a history of recurrent clinically significant respiratory infection?
boolean
C0262926 (UMLS CUI [1,1])
C2985739 (UMLS CUI [1,2])
C0035243 (UMLS CUI [1,3])
C2945760 (UMLS CUI [1,4])
Uncontrolled pulmonary hypertension
Item
Does the participant have a uncontrolled pulmonary hypertension defined by right ventricular pressure greater than 50mm Hg and/or evidenced by echocardiogram?
boolean
C0020542 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C2023445 (UMLS CUI [2,1])
C0439093 (UMLS CUI [2,2])
Severe inability to walk
Item
Does the participant have an inability to walk greater than 140 meters (150 yards) in 6 minutes?
boolean
C0560046 (UMLS CUI [1,1])
C1548772 (UMLS CUI [1,2])
Other survival-compromising disease
Item
Does the participant have evidence of other disease that may compromise survival such as lung cancer, renal failure, etc?
boolean
C0012634 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2945640 (UMLS CUI [1,3])
C0038952 (UMLS CUI [1,4])
C0684249 (UMLS CUI [2])
C0035078 (UMLS CUI [3])
Pregnant or lactating
Item
Is the participant pregnant or lactating?
boolean
C0032961 (UMLS CUI [1])
C2828358 (UMLS CUI [2])
Inability to tolerate bronchoscopy under heavy sedation or anesthesia
Item
Does the participant have an inability to tolerate bronchoscopy under heavy sedation or anesthesia?
boolean
C1299582 (UMLS CUI [1,1])
C1704410 (UMLS CUI [1,2])
C0006290 (UMLS CUI [1,3])
C4723618 (UMLS CUI [1,4])
C0235195 (UMLS CUI [1,5])
C1299582 (UMLS CUI [2,1])
C1704410 (UMLS CUI [2,2])
C0006290 (UMLS CUI [2,3])
C0002903 (UMLS CUI [2,4])
Clinically significant bronchiectasis
Item
Does the participant have clinically significant bronchiectasis?
boolean
C2985739 (UMLS CUI [1,1])
C0006267 (UMLS CUI [1,2])
Giant bullae
Item
Does the participant have a giant bullae greater than 1/3 lung volume?
boolean
C0549177 (UMLS CUI [1,1])
C0241982 (UMLS CUI [1,2])
Previous LVR surgery, lung transplant or lobectomy
Item
Does the participant had previous LVR surgery, lung transplant or lobectomy?
boolean
C0205156 (UMLS CUI [1,1])
C0375931 (UMLS CUI [1,2])
C0205156 (UMLS CUI [2,1])
C0024128 (UMLS CUI [2,2])
C0205156 (UMLS CUI [3,1])
C0023928 (UMLS CUI [3,2])
Recent pulmonary drug studies
Item
Does the participant have been involved in other pulmonary drug studies with 30 days prior to this study?
boolean
C0332185 (UMLS CUI [1,1])
C1314939 (UMLS CUI [1,2])
C2603343 (UMLS CUI [1,3])
C0024109 (UMLS CUI [1,4])
C1254351 (UMLS CUI [1,5])
Daily steroid dose
Item
Is the participant taking greater than 20 mg prednisone (or similar steroid) daily?
boolean
C0032952 (UMLS CUI [1,1])
C2348070 (UMLS CUI [1,2])
C0439093 (UMLS CUI [1,3])
Clopidogrel status
Item
Is the participant on Plavix or has not been weaned off prior to procedure?
boolean
C0070166 (UMLS CUI [1,1])
C0457083 (UMLS CUI [1,2])
C0332152 (UMLS CUI [1,3])
C0184661 (UMLS CUI [1,4])
Disease interfering with study
Item
Does the participant have other disease that would interfere with completion of study, follow up assessments or that would adversely affect outcomes?
boolean
C0205394 (UMLS CUI [1,1])
C0012634 (UMLS CUI [1,2])
C0521102 (UMLS CUI [1,3])
C2348557 (UMLS CUI [1,4])
C0205394 (UMLS CUI [2,1])
C0012634 (UMLS CUI [2,2])
C0521102 (UMLS CUI [2,3])
C1522577 (UMLS CUI [2,4])
C0205394 (UMLS CUI [3,1])
C0012634 (UMLS CUI [3,2])
C0521102 (UMLS CUI [3,3])
C1274040 (UMLS CUI [3,4])